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South America Tour & Cruise Packages Starting In April 2027

Are you planning a tour to South America in April 2027? Choose from 18 unique tour & cruise packages with 208 departures operated by South America's leading tour operators & cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the South America tour that best matches your travel style, budget and dates.
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$82,205pp
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18 Packages (208 Package Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Jun 2026 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Black Friday Sale
From
US$9,664
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Jul 2026 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$10,162
Save 250
Per Person
View Trip
13 Day Peru Splendors with Galapagos Cruise with Globus
Tour + Cruise

13 Days Lima to Guayaquil
Operated By: Globus
Departures: Jul 2026 to Nov 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
US$7,226
Save 150
Per Person
View Trip
14 Day Peru & Galapagos by Yacht with Collette
Tour + Cruise

14 Days Lima to Quito
Operated By: Collette
Departures: Apr 2026 to May 2027
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
US$9,849
Save 350
Per Person
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2026 to Oct 2027
Visit: Peru, Ecuador, Galapagos
From
US$14,690
Per Person
View Trip
21 Day South America Revealed with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

21 Days Rio de Janeiro to Quito
Operated By: Trafalgar
Departures: Aug 2026 to Nov 2026
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Sign Up Savings
Today's Deal
Exclusive Savings
From
US$11,220
Save 630
Per Person
View Trip
18 Day Land of the Incas with Galápagos Legend North and Central Cruise with Trafalgar
Tour + Cruise

18 Days Lima to Quito
Operated By: Trafalgar
Departures: Jul 2026 to Nov 2026
Visit: Peru, Ecuador
Sign Up Savings
Today's Deal
Exclusive Savings
From
US$9,361
Save 470
Per Person
View Trip
27 Day South American Discovery with Brazil's Amazon & Galápagos Cruise with Globus
Tour + Cruise

27 Days Manaus to Guayaquil
Operated By: Globus
Departures: Feb 2027 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
From
US$15,350
Per Person
View Trip
13 Day Highlights of Peru with Galápagos Legend North and Central Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Aug 2026 to Nov 2026
Visit: Peru, Ecuador, Galapagos
Sign Up Savings
Today's Deal
Exclusive Savings
From
US$7,217
Save 258
Per Person
View Trip
17 Day Machu Picchu & the Galápagos Islands aboard the Yolita with G Adventures
New ReleaseTour + Cruise

17 Days Lima to Quito
Operated By: G Adventures
Departures: Aug 2026 to Dec 2027
Visit: Peru, Ecuador, Galapagos
From
US$8,699
Per Person
View Trip
23 Day South American Discovery with Galápagos Cruise with Globus
Tour + Cruise

23 Days Rio de Janeiro to Guayaquil
Operated By: Globus
Departures: Nov 2026 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$12,485
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operated By: Exodus Tours
Departures: May 2026 to Dec 2027
Visit: Ecuador, Galapagos
Sign Up Savings
Exclusive Savings
From
US$5,865
Save 1,033
Per Person
View Trip
19 Day Legacy of the Incas with Galapagos Cruise with Globus
Tour + Cruise

19 Days Lima to Guayaquil
Operated By: Globus
Departures: Jul 2026 to Sep 2026
Visit: Peru, Ecuador, Galapagos
Exclusive Savings
From
US$10,910
Save 500
Per Person
View Trip
7 Day Independent Galapagos Cruise Aboard the Galapagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operated By: Globus
Departures: Apr 2026 to Mar 2027
Visit: Ecuador, Galapagos
From
US$5,199
Per Person
View Trip
17 Day Peru Splendors with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

17 Days Lima to Guayaquil
Operated By: Globus
Departures: Jul 2026 to Nov 2027
Visit: Peru, Ecuador, Galapagos
From
US$8,635
Per Person
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Guayaquil or Lima to Quito
Operated By: Tauck
Ships: Silver Origin
Departures: Sep 2026 to Oct 2027
Visit: Peru, Ecuador, Galapagos
Inside
-
Oceanview
-
Balcony
$16,990
Suite
$29,235
From
US$16,990
Per Person
View Trip
11 Day Independent Galapagos Cruise Aboard the Galápagos Legend with Ecuador's Amazon with Globus
New ReleaseTour + Cruise

11 Days Quito to Guayaquil
Operated By: Globus
Departures: Apr 2026 to Mar 2027
Visit: Ecuador, Galapagos
From
US$7,559
Per Person
View Trip
23 Day Legacy of the Incas with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

23 Days Lima to Guayaquil
Operated By: Globus
Departure: 24 July 2026
Visit: Peru, Ecuador, Galapagos
From
US$12,719
Per Person
View Trip
Results: 18 results

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