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South America Tour & Cruise Packages Starting In April 2027 and 2028

Are you planning a tour to South America in April 2027 or 2028? Choose from 11 unique tour & cruise packages with 100 departures operated by South America's leading tour operators & cruise lines. Easily compare prices, itineraries, inclusions and traveler reviews to find the South America tour that best matches your travel style, budget and dates.
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$5,100pp
$82,205pp
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11 Packages (100 Package Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Nov 2026 to Oct 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
From
US$9,664
Per Person
View Trip
26 Day Ultimate South America with Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Nov 2026 to Nov 2027
Visit: Brazil, Argentina, Peru, Ecuador, Galapagos
Exclusive Savings
From
US$10,482
Per Person
View Trip
19 Day Legacy of the Incas with Galapagos Cruise with Globus
Tour + Cruise

19 Days Lima to Guayaquil
Operated By: Globus
Departure: 22 September 2026
Visit: Peru, Ecuador, Galapagos
From
US$11,410
Per Person
View Trip
14 Day Peru & Galapagos by Yacht with Collette
Tour + Cruise

14 Days Lima to Quito
Operated By: Collette
Departures: Aug 2026 to May 2027
Visit: Peru, Ecuador, Galapagos
Flash Sale
Exclusive Savings
From
US$9,799
Save 400
Per Person
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17 Day Machu Picchu & the Galápagos Islands aboard the Yolita with G Adventures
New ReleaseTour + Cruise

17 Days Lima to Quito
Operated By: G Adventures
Departures: Jun 2026 to Dec 2027
Visit: Peru, Ecuador, Galapagos
From
US$8,699
Per Person
View Trip
13 Day Peru Splendors with Galapagos Cruise with Globus
Tour + Cruise

13 Days Lima to Guayaquil
Operated By: Globus
Departures: Aug 2026 to Nov 2026
Visit: Peru, Ecuador, Galapagos
From
US$7,376
Per Person
View Trip
26 Day Best of South America with Galápagos Cruise with APT
New ReleaseTour + Cruise

26 Days Rio de Janeiro to Guayaquil
Operated By: APT
Departures: Apr 2027 to Nov 2028
Visit: Brazil, Argentina, Chile, Peru, Ecuador, Galapagos
From
US$24,795
Per Person
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Sep 2026 to Oct 2027
Visit: Peru, Ecuador, Galapagos
From
US$14,790
Per Person
View Trip
15 Day Highlights of Ecuador & the Galapagos with Exodus Tours
New ReleaseTour + Cruise

15 Days Quito to Quito
Operated By: Exodus Tours
Departures: Jun 2026 to Dec 2027
Visit: Ecuador, Galapagos
Sign Up Savings
Exclusive Savings
From
US$5,865
Save 1,033
Per Person
View Trip
17 Day Peru Splendors with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

17 Days Lima to Guayaquil
Operated By: Globus
Departures: Aug 2026 to Nov 2026
Visit: Peru, Ecuador, Galapagos
From
US$8,635
Per Person
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Quito or Lima to Guayaquil
Operated By: Tauck
Ships: Silver Origin
Departures: Sep 2026 to Oct 2027
Visit: Peru, Ecuador, Galapagos
From
US$17,990
Per Person
View Trip
Results: 11 results

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