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MSC South America Cruises

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122 Days
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85 Cruises (177 Cruise Departures)
122 Day MSC World Cruise with MSC Cruises
Cruise

122 Days (121 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 07 January 2027
Visit: Spain, Gibraltar, Morocco, Cape Verde (+20 more), Brazil, Argentina, Falkland Islands, Chile, French Polynesia, Cook Islands, New Zealand, Australia, New Caledonia, Vanuatu, American Samoa, USA, Mexico, Costa Rica, Panama, Jamaica, Virgin Islands, Saint Martin, Italy, France
Inside
$17,049
Oceanview
$20,009
Balcony
$29,059
Suite
-
From
US$17,049
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 31 December 2026
Visit: Brazil, Uruguay, Argentina
Inside
-
Oceanview
-
Balcony
$2,344
Suite
$3,064
From
US$2,344
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Buenos Aires to Bari
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 31 March 2027
Visit: Argentina, Brazil, Spain, Corsica, Italy, Greece
Inside
$1,751
Oceanview
$2,171
Balcony
$2,431
Suite
$3,751
From
US$1,751
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Barcelona to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 16 November 2027
Visit: Spain, Brazil
Inside
$1,507
Oceanview
$1,847
Balcony
$2,127
Suite
$4,557
From
US$1,507
Per Person
View Trip
116 Day MSC World Cruise with MSC Cruises
Cruise

116 Days (115 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 05 January 2028
Visit: Italy, France, Spain, Turks and Caicos Islands (+24 more), Bahamas, Mexico, Costa Rica, Panama, Ecuador, Peru, Chile, French Polynesia, Tonga, New Caledonia, New Zealand, Australia, Indonesia, Vietnam, Thailand, Cambodia, Singapore, Malaysia, Sri Lanka, India, United Arab Emirates, Oman, Jordan, Egypt
Inside
$19,889
Oceanview
$21,609
Balcony
$27,909
Suite
$75,017
From
US$19,889
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Buenos Aires to Trieste
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 31 March 2027
Visit: Argentina, Brazil, Spain, Corsica, Italy, Greece
Inside
$1,844
Oceanview
$2,274
Balcony
$2,544
Suite
$3,924
From
US$1,844
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Sao Paulo to Salvador
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 05 December 2026
Visit: Brazil
Inside
$485
Oceanview
$605
Balcony
$677
Suite
$1,085
From
US$485
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 05 January 2027
Visit: Argentina, Brazil, Uruguay
Inside
$1,639
Oceanview
$1,991
Balcony
$2,167
Suite
$2,871
From
US$1,639
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Amalfi to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 14 November 2027
Visit: Italy, Spain, Brazil, Uruguay, Argentina
Inside
$2,013
Oceanview
$2,513
Balcony
$2,723
Suite
$4,653
From
US$2,013
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Rio de Janeiro to Marseille
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 04 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily, Italy, France
Inside
$1,774
Oceanview
$2,274
Balcony
$2,754
Suite
$8,324
From
US$1,774
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Buenos Aires to Rome
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 31 March 2027
Visit: Argentina, Brazil, Spain, Corsica, Italy
Inside
$1,487
Oceanview
$1,847
Balcony
$2,087
Suite
$3,527
From
US$1,487
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Mar 2027
Visit: Brazil
Inside
$972
Oceanview
$1,052
Balcony
$1,167
Suite
$1,604
From
US$972
Per Person
View Trip
116 Day MSC World Cruise with MSC Cruises
Cruise

116 Days (115 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 04 January 2028
Visit: Italy, France, Spain, Turks and Caicos Islands (+24 more), Bahamas, Mexico, Costa Rica, Panama, Ecuador, Peru, Chile, French Polynesia, Tonga, New Caledonia, New Zealand, Australia, Indonesia, Vietnam, Thailand, Cambodia, Singapore, Malaysia, Sri Lanka, India, United Arab Emirates, Oman, Jordan, Egypt
Inside
$18,749
Oceanview
$21,609
Balcony
$27,909
Suite
$75,017
From
US$18,749
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Barcelona to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 15 November 2026
Visit: Spain, Gibraltar, Morocco, Brazil, Uruguay, Argentina
Inside
$1,627
Oceanview
$1,987
Balcony
$2,167
Suite
$3,577
From
US$1,627
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Florence to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 10 November 2026
Visit: Italy, Sardinia, Sicily, Malta (+6 more), Spain, Gibraltar, Morocco, Brazil, Uruguay, Argentina
Inside
-
Oceanview
-
Balcony
-
Suite
$4,239
From
US$4,239
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Santos to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily, Italy
Inside
$1,681
Oceanview
$2,031
Balcony
$2,601
Suite
-
From
US$1,681
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Amalfi to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 13 November 2027
Visit: Italy, France, Spain, Brazil
Drinks & WiFi Package
Inside
-
Oceanview
-
Balcony
-
Suite
$8,183
From
US$8,183
Per Person
View Trip
116 Day MSC World Cruise with MSC Cruises
Cruise

116 Days (115 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 06 January 2028
Visit: France, Spain, Turks and Caicos Islands, Bahamas (+24 more), Mexico, Costa Rica, Panama, Ecuador, Peru, Chile, French Polynesia, Tonga, New Caledonia, New Zealand, Australia, Indonesia, Vietnam, Thailand, Cambodia, Singapore, Malaysia, Sri Lanka, India, United Arab Emirates, Oman, Jordan, Egypt, Italy
Inside
$19,709
Oceanview
$22,379
Balcony
$27,909
Suite
$46,439
From
US$19,709
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Cagliari to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 11 November 2026
Visit: Sardinia, Sicily, Malta, Spain (+5 more), Gibraltar, Morocco, Brazil, Uruguay, Argentina
Inside
$2,004
Oceanview
$2,434
Balcony
$2,704
Suite
-
From
US$2,004
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 27 December 2026
Visit: Argentina, Brazil, Uruguay
Inside
$2,068
Oceanview
$2,420
Balcony
$2,563
Suite
$3,300
From
US$2,068
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Salvador to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 30 March 2027
Visit: Brazil
Inside
$535
Oceanview
$627
Balcony
$742
Suite
$1,236
From
US$535
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Palermo to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 12 November 2026
Visit: Sicily, Malta, Spain, Gibraltar (+4 more), Morocco, Brazil, Uruguay, Argentina
Inside
-
Oceanview
-
Balcony
-
Suite
$4,231
From
US$4,231
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Maceio to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Mar 2027
Visit: Brazil
Inside
$420
Oceanview
$489
Balcony
$569
Suite
$949
From
US$420
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Rio de Janeiro to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 04 April 2027
Visit: Brazil, Spain, Morocco
Inside
$1,289
Oceanview
$1,549
Balcony
$1,779
Suite
$6,179
From
US$1,289
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: Dec 2026 to Mar 2027
Visit: Argentina, Brazil, Uruguay
Inside
$1,249
Oceanview
$1,557
Balcony
$1,689
Suite
$2,338
From
US$1,249
Per Person
View Trip
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