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MSC South America Cruises

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89 Cruises (231 Cruise Departures)
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Rio de Janeiro to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 04 April 2027
Visit: Brazil, Spain, Morocco
Bonus Onboard Credit
Inside
$1,289
Oceanview
$1,549
Balcony
$1,779
Suite
-
From
US$1,289
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Palermo to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 12 November 2027
Visit: Sicily, Italy, France, Spain, Brazil
Drinks, WiFi & Onboard Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$8,335
From
US$8,335
Save 240
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Palermo to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 12 November 2026
Visit: Sicily, Malta, Spain, Gibraltar (+4 more), Morocco, Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$1,911
Oceanview
-
Balcony
$2,531
Suite
$4,122
From
US$1,911
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Jan 2027
Visit: Brazil
Inside
$689
Oceanview
$773
Balcony
$881
Suite
$1,409
From
US$689
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Maceio to Maceio
Cruise Line: MSC Cruises
Ships: MSC Seaview, MSC Virtuosa
Departures: Feb 2026 to Mar 2027
Visit: Brazil
Bonus Onboard Credit
Inside
$961
Oceanview
$1,027
Balcony
$1,165
Suite
$1,579
From
US$961
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Sao Paulo to Salvador
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 05 December 2026
Visit: Brazil
Inside
$521
Oceanview
$605
Balcony
$689
Suite
$1,085
From
US$521
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Armonia
Departures: Feb 2026 to Mar 2026
Visit: Brazil
Bonus Onboard Credit
Exclusive Savings
Inside
$965
Oceanview
$1,075
Balcony
$1,629
Suite
$1,917
From
US$965
Save 55
Per Person
View Trip
6 Day MSC Grand Voyages with MSC Cruises
Cruise

6 Days (5 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Visit: Brazil
Inside
-
Oceanview
-
Balcony
$654
Suite
-
From
US$654
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ships: MSC Seaview, MSC Virtuosa
Departures: Feb 2026 to Mar 2027
Visit: Brazil
Bonus Onboard Credit
Inside
$973
Oceanview
$1,027
Balcony
$1,165
Suite
$1,579
From
US$973
Per Person
View Trip
122 Day MSC World Cruise with MSC Cruises
Cruise

122 Days (121 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 05 January 2027
Visit: Italy, France, Spain, Gibraltar (+20 more), Morocco, Cape Verde, Brazil, Argentina, Falkland Islands, Chile, French Polynesia, Cook Islands, New Zealand, Australia, New Caledonia, Vanuatu, American Samoa, USA, Mexico, Costa Rica, Panama, Jamaica, Virgin Islands, Saint Martin
Exclusive Savings
Inside
$16,622
Oceanview
$19,493
Balcony
$28,272
Suite
-
From
US$16,622
Save 427
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: Dec 2026 to Mar 2027
Visit: Argentina, Brazil, Uruguay
Bonus Onboard Credit
Inside
$1,076
Oceanview
$1,307
Balcony
$1,439
Suite
$2,031
From
US$1,076
Per Person
View Trip
22 Day MSC World Cruise with MSC Cruises
Cruise

22 Days (21 Nights) Genoa to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 05 January 2027
Visit: Italy, France, Spain, Gibraltar (+4 more), Morocco, Cape Verde, Brazil, Argentina
Exclusive Savings
Inside
$12,283
Oceanview
$14,339
Balcony
-
Suite
-
From
US$12,283
Save 316
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco
Bonus Onboard Credit
Inside
$1,394
Oceanview
$1,664
Balcony
$1,894
Suite
$5,265
From
US$1,394
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Genoa to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 15 November 2027
Visit: Italy, Spain, Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$1,969
Oceanview
$2,382
Balcony
$2,595
Suite
$4,060
From
US$1,969
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Buenos Aires to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 11 March 2027
Visit: Argentina, Brazil
Inside
$289
Oceanview
$379
Balcony
$439
Suite
$719
From
US$289
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Salvador to Salvador
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 29 December 2026
Visit: Brazil
Bonus Onboard Credit
Inside
$1,832
Oceanview
$1,839
Balcony
$1,950
Suite
$2,374
From
US$1,832
Per Person
View Trip
122 Day MSC World Cruise with MSC Cruises
Cruise

122 Days (121 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 06 January 2027
Visit: France, Spain, Gibraltar, Morocco (+20 more), Cape Verde, Brazil, Argentina, Falkland Islands, Chile, French Polynesia, Cook Islands, New Zealand, Australia, New Caledonia, Vanuatu, American Samoa, USA, Mexico, Costa Rica, Panama, Jamaica, Virgin Islands, Saint Martin, Italy
Exclusive Savings
Inside
$16,622
Oceanview
$19,493
Balcony
$28,272
Suite
-
From
US$16,622
Save 427
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Santos to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily, Italy
Bonus Onboard Credit
Inside
$1,791
Oceanview
$2,031
Balcony
$2,337
Suite
$7,750
From
US$1,791
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Amalfi to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 14 November 2027
Visit: Italy, Spain, Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$2,013
Oceanview
$2,455
Balcony
$2,659
Suite
$4,531
From
US$2,013
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 10 February 2027
Visit: Argentina, Brazil, Uruguay
Bonus Onboard Credit
Inside
$1,356
Oceanview
$1,631
Balcony
$1,774
Suite
$2,444
From
US$1,356
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 26 December 2026
Visit: Brazil
Bonus Onboard Credit
Inside
$1,834
Oceanview
$1,864
Balcony
$1,998
Suite
$13,207
From
US$1,834
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Santos to Palermo
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily
Bonus Onboard Credit
Inside
$1,709
Oceanview
$2,049
Balcony
$2,188
Suite
$7,397
From
US$1,709
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Sao Paulo to São Paulo
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 29 November 2026
Visit: Brazil
Bonus Onboard Credit
Inside
$585
Oceanview
$645
Balcony
$753
Suite
$993
From
US$585
Per Person
View Trip
6 Day South America with MSC Cruises
Cruise

6 Days (5 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 21 December 2026
Visit: Brazil
Bonus Onboard Credit
Inside
$894
Oceanview
$952
Balcony
$1,078
Suite
$1,331
From
US$894
Per Person
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: Jan 2027 to Feb 2027
Visit: Argentina, Brazil, Uruguay
Bonus Onboard Credit
Inside
$1,367
Oceanview
$1,642
Balcony
$1,818
Suite
$2,455
From
US$1,367
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ships: MSC Seaview, MSC Virtuosa
Departures: Feb 2026 to Mar 2027
Visit: Brazil
Bonus Onboard Credit
Inside
$700
Oceanview
$878
Balcony
$1,120
Suite
$1,604
From
US$700
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise

2 Days (1 Nights) Santos to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Preziosa
Departure: 02 April 2026
Visit: Brazil
Drinks & WiFi Package
Inside
$133
Oceanview
$196
Balcony
$238
Suite
$406
From
US$133
Per Person
View Trip
116 Day MSC World Cruise with MSC Cruises
Cruise

116 Days (115 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 05 January 2028
Visit: Italy, France, Spain, Turks and Caicos Islands (+24 more), Bahamas, Mexico, Costa Rica, Panama, Ecuador, Peru, Chile, French Polynesia, Tonga, New Caledonia, New Zealand, Australia, Indonesia, Vietnam, Thailand, Cambodia, Singapore, Malaysia, Sri Lanka, India, United Arab Emirates, Oman, Jordan, Egypt
Exclusive Savings
Inside
$19,198
Oceanview
$21,041
Balcony
$27,152
Suite
$69,386
From
US$19,198
Save 511
Per Person
View Trip
116 Day MSC World Cruise with MSC Cruises
Cruise

116 Days (115 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 07 January 2028
Visit: Spain, Turks and Caicos Islands, Bahamas, Mexico (+24 more), Costa Rica, Panama, Ecuador, Peru, Chile, French Polynesia, Tonga, New Caledonia, New Zealand, Australia, Indonesia, Vietnam, Thailand, Cambodia, Singapore, Malaysia, Sri Lanka, India, United Arab Emirates, Oman, Jordan, Egypt, Italy, France
Exclusive Savings
Inside
$19,198
Oceanview
$21,788
Balcony
$29,567
Suite
-
From
US$19,198
Save 511
Per Person
View Trip
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