Start your journey from Sao Paulo with 6 unique MSC cruise itineraries to choose from. December is the most popular month to begin your cruise from Sao Paulo and MSC Cruises have 56 trips departing this season.
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Departures
Feb 2026 (2) Mar 2026 (2) Apr 2026 (1) Nov 2026 (3) Dec 2026 (5) Jan 2027 (3) Feb 2027 (3)
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