MSC Cruises from Rome

Start your journey from Rome with 26 unique MSC cruise itineraries to choose from. October is the most popular month to begin your cruise from Rome and MSC Cruises have 198 trips departing this season.
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26 Cruises (198 Departures)
26 Cruises (198 Departures)
Departures
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Duration
4 Days
25 Days
Price
$400pp
$3,769pp
Countries
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Cruise
 (1)

18 Days (17 Nights) Rome to Rio de Janeiro
Operator: MSC Cruises
Ship: MSC Divina
Departure: 29 October 2027
Visits: Italy, France, Spain, Brazil
Exclusive Savings
Inside
$2,542
Oceanview
$2,859
Balcony
$3,265
Suite
$5,176
From (Per Person)
A$2,542
Per Person
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Operator: MSC Cruises
Ship: MSC Lirica
Departures: Nov 2027 to Mar 2028
Visits: Italy, Spain, France
Exclusive Savings
Inside
$1,132
Oceanview
$1,281
Balcony
$1,756
Suite
$2,152
From (Per Person)
A$1,132
Save 21
Per Person
Cruise
 (1)

5 Days (4 Nights) Rome to Rome
Operator: MSC Cruises
Ship: MSC Divina
Departure: 10 November 2028
Visits: Italy, Spain, France
Exclusive Savings
Inside
$824
Oceanview
$972
Balcony
$1,061
Suite
$1,487
From (Per Person)
A$824
Per Person
Cruise
 (3)

8 Days (7 Nights) Rome to Rome
Operator: MSC Cruises
Departures: May 2027 to Nov 2028
Visits: Italy, Spain, France
Exclusive Savings
Inside
$1,647
Oceanview
$1,974
Balcony
$2,172
Suite
$3,132
From (Per Person)
A$1,647
Per Person
Cruise
 (2)

7 Days (6 Nights) Rome to Santa Cruz De Tenerife
Operator: MSC Cruises
Ship: MSC Fantasia
Departure: 07 December 2026
Visits: Italy, Spain
Exclusive Savings
Inside
$775
Oceanview
$864
Balcony
$864
Suite
$1,577
From (Per Person)
A$775
Per Person
Cruise
 (1)

14 Days (13 Nights) Rome to Salvador
Operator: MSC Cruises
Ship: MSC Divina
Departure: 29 October 2027
Visits: Italy, France, Spain, Brazil
Exclusive Savings
Inside
-
Oceanview
$2,303
Balcony
$2,739
Suite
$4,303
From (Per Person)
A$2,303
Per Person
Cruise
 (1)

19 Days (18 Nights) Rome to Santos
Operator: MSC Cruises
Ship: MSC Divina
Departure: 29 October 2027
Visits: Italy, France, Spain, Brazil
Exclusive Savings
Inside
$2,612
Oceanview
$3,196
Balcony
$3,473
Suite
$5,503
From (Per Person)
A$2,612
Per Person
Cruise
 (2)

9 Days (8 Nights) Rome to Funchal
Operator: MSC Cruises
Ship: MSC Fantasia
Departure: 07 December 2026
Visits: Italy, Spain, Portugal
Exclusive Savings
Inside
$1,014
Oceanview
$1,074
Balcony
$1,182
Suite
$2,559
From (Per Person)
A$1,014
Per Person
Cruise
 (2)

4 Days (3 Nights) Rome to Barcelona
Operator: MSC Cruises
Ship: MSC Fantasia
Departure: 12 April 2027
Visits: Italy, France, Spain
Exclusive Savings
Inside
-
Oceanview
$417
Balcony
$477
Suite
$853
From (Per Person)
A$417
Per Person
Cruise
 (1)

25 Days (24 Nights) Rome to Santos
Operator: MSC Cruises
Ship: MSC Musica
Departure: 31 October 2027
Visits: Italy, Sicily, Spain, France, Portugal, Brazil
Exclusive Savings
Inside
-
Oceanview
$3,742
Balcony
$4,613
Suite
$10,394
From (Per Person)
A$3,742
Per Person
Cruise
 (3)

6 Days (5 Nights) Rome to Genoa
Operator: MSC Cruises
Departure: 09 November 2026
Visits: Italy, Sicily, Spain, France
Exclusive Savings
Inside
$903
Oceanview
-
Balcony
$1,151
Suite
$4,997
From (Per Person)
A$903
Per Person
Cruise
 (2)

12 Days (11 Nights) Rome to Las Palmas de Gran Canaria
Operator: MSC Cruises
Ship: MSC Fantasia
Departure: 07 December 2026
Visits: Italy, Spain, Portugal
Exclusive Savings
Inside
$1,213
Oceanview
$1,401
Balcony
$1,649
Suite
$3,450
From (Per Person)
A$1,213
Per Person
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Operator: MSC Cruises
Ship: MSC Divina
Departures: Aug 2027 to Sep 2027
Visits: Italy, Greece, Turkey
Exclusive Savings
Inside
$1,508
Oceanview
$1,716
Balcony
$1,934
Suite
$2,865
From (Per Person)
A$1,508
Per Person
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Operator: MSC Cruises
Ship: MSC Divina
Departures: May 2027 to Sep 2028
Visits: Italy, Greece, Turkey
Exclusive Savings
Inside
$1,380
Oceanview
$1,578
Balcony
$1,786
Suite
$2,627
From (Per Person)
A$1,380
Per Person
Cruise
 (3)

8 Days (7 Nights) Rome to Rome
Operator: MSC Cruises
Departures: Jan 2027 to Apr 2028
Visits: Italy, Sicily, Malta, Spain, France
Exclusive Savings
Inside
$885
Oceanview
$1,093
Balcony
$1,162
Suite
$2,320
From (Per Person)
A$885
Save 16
Per Person
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Operator: MSC Cruises
Ship: MSC Lirica
Departure: 02 December 2027
Visits: Italy, Spain, France
Exclusive Savings
Inside
$1,162
Oceanview
$1,310
Balcony
$1,786
Suite
$2,182
From (Per Person)
A$1,162
Per Person
Cruise
 (2)

8 Days (7 Nights) Rome to Rome
Operator: MSC Cruises
Ship: MSC Fantasia
Departures: Apr 2027 to Sep 2028
Visits: Italy, France, Spain, Sardinia
Exclusive Savings
Inside
$1,202
Oceanview
$1,281
Balcony
$1,340
Suite
$2,221
From (Per Person)
A$1,202
Save 19
Per Person
Cruise
 (2)

11 Days (10 Nights) Rome to Lanzarote
Operator: MSC Cruises
Ship: MSC Fantasia
Departure: 07 December 2026
Visits: Italy, Spain, Portugal
Exclusive Savings
Inside
$1,272
Oceanview
-
Balcony
-
Suite
$5,203
From (Per Person)
A$1,272
Per Person
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Operator: MSC Cruises
Ship: MSC Divina
Departures: Jul 2027 to Sep 2027
Visits: Italy, Greece, Turkey
Exclusive Savings
Inside
$1,598
Oceanview
$1,865
Balcony
$2,083
Suite
$2,795
From (Per Person)
A$1,598
Per Person
Cruise
 (3)

21 Days (20 Nights) Rome to Fort-de-France
Operator: MSC Cruises
Departure: 15 November 2026
Visits: Italy, France, Spain, Saint Martin +5 more, Saint Kitts and Nevis, Saint Vincent, Barbados, Grenada, Martinique
Exclusive Savings
Inside
$1,553
Oceanview
$1,900
Balcony
$2,286
Suite
$5,949
From (Per Person)
A$1,553
Per Person
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Operator: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2028
Visits: Italy, Sicily, Spain, France
Exclusive Savings
Inside
$1,063
Oceanview
$1,152
Balcony
$1,419
Suite
$2,874
From (Per Person)
A$1,063
Save 17
Per Person
Cruise

8 Days (7 Nights) Rome to Rome
Operator: MSC Cruises
Departures: May 2028 to Oct 2028
Visits: Italy, France, Spain
Exclusive Savings
Inside
$1,459
Oceanview
$1,588
Balcony
$1,716
Suite
$3,617
From (Per Person)
A$1,459
Per Person
Cruise

11 Days (10 Nights) Rome to Rome
Operator: MSC Cruises
Departure: 25 November 2027
Visits: Italy, France, Spain, Morocco
Exclusive Savings
Inside
$1,896
Oceanview
$2,183
Balcony
$2,440
Suite
$3,945
From (Per Person)
A$1,896
Per Person
Cruise

14 Days (13 Nights) Rome to Rome
Operator: MSC Cruises
Ship: MSC Sinfonia
Departure: 14 April 2027
Visits: Italy, Spain, France, Morocco, Portugal
Exclusive Savings
Inside
$1,561
Oceanview
$1,769
Balcony
-
Suite
$3,432
From (Per Person)
A$1,561
Per Person
Cruise

11 Days (10 Nights) Rome to Rome
Operator: MSC Cruises
Departures: Nov 2027 to Dec 2027
Visits: Italy, France, Spain, Morocco
Exclusive Savings
Inside
$1,678
Oceanview
$1,965
Balcony
$2,223
Suite
$3,727
From (Per Person)
A$1,678
Per Person
Cruise

11 Days (10 Nights) Rome to Rome
Operator: MSC Cruises
Departure: 25 December 2027
Visits: Italy, France, Spain, Morocco
Exclusive Savings
Inside
$3,589
Oceanview
$3,876
Balcony
$4,133
Suite
$5,806
From (Per Person)
A$3,589
Per Person
Results: 26 results

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