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MSC Cruises from Rome

Start your journey from Rome with 55 unique MSC cruise itineraries to choose from. October is the most popular month to begin your cruise from Rome and MSC Cruises have 344 trips departing this season.
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Duration
4 Days
116 Days
Price
$200pp
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55 Cruises (344 Cruise Departures)
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC World Asia
Departures: Dec 2026 to Mar 2028
Visit: Italy, Sicily, Malta, Spain, France
Inside
$696
Oceanview
$926
Balcony
$1,016
Suite
$1,756
From
US$696
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Sinfonia
Departures: Nov 2026 to Mar 2028
Visit: Italy, Spain, France
Inside
$502
Oceanview
$662
Balcony
$972
Suite
$1,242
From
US$502
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: May 2026 to Oct 2026
Visit: Italy, Spain, France
Inside
$875
Oceanview
$1,025
Balcony
$1,225
Suite
$2,095
From
US$875
Per Person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Rome to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: Jun 2026 to Apr 2027
Visit: Italy, Greece, Turkey
Inside
$624
Oceanview
$590
Balcony
$730
Suite
-
From
US$590
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Jun 2026 to Sep 2026
Visit: Italy, France, Spain, Sardinia
Inside
$1,002
Oceanview
$1,022
Balcony
$1,262
Suite
$1,962
From
US$1,002
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

23 Days (22 Nights) Rome to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 31 October 2027
Visit: Italy, Sicily, Spain, France, Portugal, Brazil
Inside
-
Oceanview
$2,045
Balcony
$2,835
Suite
-
From
US$2,045
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

21 Days (20 Nights) Rome to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 15 November 2026
Visit: Italy, France, Spain, Saint Martin (+5 more), Saint Kitts and Nevis, Saint Vincent, Barbados, Grenada, Martinique
Inside
$1,449
Oceanview
$1,829
Balcony
$2,009
Suite
-
From
US$1,449
Per Person
View Trip
9 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (2)

9 Days (8 Nights) Rome to Funchal
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 07 December 2026
Visit: Italy, Spain, Portugal
Inside
$717
Oceanview
$717
Balcony
$717
Suite
$1,671
From
US$717
Per Person
View Trip
7 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (2)

7 Days (6 Nights) Rome to Santa Cruz De Tenerife
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 07 December 2026
Visit: Italy, Spain
Inside
$484
Oceanview
$484
Balcony
$484
Suite
$864
From
US$484
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Rome to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 30 October 2026
Visit: Italy, Spain, Brazil
Inside
$1,230
Oceanview
$1,419
Balcony
$1,704
Suite
$2,905
From
US$1,230
Per Person
View Trip
26 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

26 Days (25 Nights) Rome to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 22 October 2027
Visit: Italy, Greece, Turkey, France, Spain, Brazil
Inside
-
Oceanview
$2,850
Balcony
$3,060
Suite
$5,280
From
US$2,850
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Italy, Sicily, Spain, France
Inside
$831
Oceanview
$921
Balcony
$1,101
Suite
-
From
US$831
Per Person
View Trip
11 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (2)

11 Days (10 Nights) Rome to Lanzarote
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 07 December 2026
Visit: Italy, Spain, Portugal
Inside
$683
Oceanview
$870
Balcony
$907
Suite
$3,679
From
US$683
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: May 2026 to Oct 2026
Visit: Italy, France, Spain
Inside
$683
Oceanview
$803
Balcony
$1,173
Suite
$1,823
From
US$683
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Rome to Salvador
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 30 October 2026
Visit: Italy, Spain, Brazil
Inside
$1,103
Oceanview
$1,244
Balcony
$1,480
Suite
$2,408
From
US$1,103
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Visit: Italy, Sicily, Spain, France
Drinks & WiFi Package
Inside
$1,059
Oceanview
$1,189
Balcony
$1,329
Suite
$1,839
From
US$1,059
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Rome to Miami
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 28 October 2026
Visit: Italy, Spain, Portugal, Puerto Rico, USA
Inside
$888
Oceanview
$1,131
Balcony
$1,346
Suite
-
From
US$888
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (3)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC World Europa
Departures: Oct 2026 to Oct 2027
Visit: Italy, Spain, France
Inside
$1,254
Oceanview
$1,295
Balcony
$1,584
Suite
$2,115
From
US$1,254
Per Person
View Trip
12 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (2)

12 Days (11 Nights) Rome to Las Palmas de Gran Canaria
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 07 December 2026
Visit: Italy, Spain, Portugal
Inside
$692
Oceanview
$898
Balcony
$1,146
Suite
$2,349
From
US$692
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Divina
Departures: May 2026 to Oct 2027
Visit: Italy, Greece, Turkey
Inside
$311
Oceanview
$470
Balcony
$610
Suite
$1,129
From
US$311
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Rome to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 29 October 2027
Visit: Italy, France, Spain, Brazil
Inside
$1,454
Oceanview
$1,724
Balcony
$2,004
Suite
$3,284
From
US$1,454
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Rome to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 28 October 2026
Visit: Italy, Spain, Portugal, Puerto Rico, USA
Inside
$952
Oceanview
$1,267
Balcony
$1,505
Suite
-
From
US$952
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

24 Days (23 Nights) Rome to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 31 October 2027
Visit: Italy, Sicily, Spain, France, Portugal, Brazil
Inside
-
Oceanview
$2,139
Balcony
$2,959
Suite
-
From
US$2,139
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Rome to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 30 October 2026
Visit: Italy, Spain, Brazil
Inside
$1,324
Oceanview
$1,493
Balcony
$2,078
Suite
$3,304
From
US$1,324
Per Person
View Trip
7 Day Canary Islands And Madeira with MSC Cruises
Cruise
 (2)

7 Days (6 Nights) Rome to Santa Cruz De Tenerife
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 15 November 2027
Visit: Italy, Spain
Inside
$549
Oceanview
$639
Balcony
$719
Suite
$1,149
From
US$549
Per Person
View Trip
14 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

14 Days (13 Nights) Rome to Salvador
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 29 October 2027
Visit: Italy, France, Spain, Brazil
Inside
$1,144
Oceanview
$1,324
Balcony
$1,564
Suite
$2,754
From
US$1,144
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

19 Days (18 Nights) Rome to Doha
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 21 November 2027
Visit: Italy, Greece, Turkey, Cyprus, Egypt, Oman, Qatar
Inside
$1,667
Oceanview
$1,967
Balcony
$2,437
Suite
$4,567
From
US$1,667
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Apr 2027 to Nov 2027
Visit: Italy, France, Spain, Sardinia
Inside
$822
Oceanview
$952
Balcony
$1,022
Suite
$1,512
From
US$822
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise
 (3)

21 Days (20 Nights) Rome to Dubai
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 21 November 2027
Visit: Italy, Greece, Turkey, Cyprus (+4 more), Egypt, Oman, Qatar, United Arab Emirates
Inside
$1,849
Oceanview
$2,189
Balcony
$2,709
Suite
$5,059
From
US$1,849
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 30 October 2026
Visit: Italy, Spain
Inside
$356
Oceanview
$450
Balcony
$510
Suite
$804
From
US$356
Per Person
View Trip
Results: 1-30 of 55

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