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MSC Cruises from Florence

Start your journey from Florence with 7 unique MSC cruise itineraries to choose from. April, October and November are the most popular months to begin your cruise from Florence and MSC Cruises have 71 trips departing this season.
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7 Cruises (71 Cruise Departures)
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Feb 2026 to Apr 2026
Visit: Italy, Spain, France
Bonus Onboard Credit
Inside
$527
Oceanview
$653
Balcony
$834
Suite
-
From
US$527
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Apr 2027 to Nov 2027
Visit: Italy, France, Spain, Sardinia
Bonus Onboard Credit
Inside
$807
Oceanview
$957
Balcony
$1,047
Suite
$1,767
From
US$807
Per Person
View Trip
25 Day Msc Grand Voyages with MSC Cruises
Cruise

25 Days (24 Nights) Florence to Miami
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 18 October 2026
Visit: Italy, France, Spain, Gibraltar, Morocco, Portugal, USA
Bonus Onboard Credit
Inside
$1,939
Oceanview
$2,289
Balcony
$2,561
Suite
$6,528
From
US$1,939
Per Person
View Trip
9 Day Mediterranean with MSC Cruises
Cruise

9 Days (8 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 27 April 2026
Visit: Italy, Sardinia, Sicily, Malta, Spain, France
Inside
$1,084
Oceanview
$1,260
Balcony
-
Suite
-
From
US$1,084
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: May 2026 to Nov 2026
Visit: Italy, Sardinia, Sicily, Malta, Spain, France
Bonus Onboard Credit
Inside
$927
Oceanview
$944
Balcony
$1,147
Suite
$1,514
From
US$927
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Florence to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 10 November 2026
Visit: Italy, Sardinia, Sicily, Malta (+6 more), Spain, Gibraltar, Morocco, Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$2,219
Oceanview
-
Balcony
$2,803
Suite
$4,132
From
US$2,219
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Florence to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 14 November 2027
Visit: Italy, France, Spain, Brazil
Bonus Onboard Credit
Inside
$1,449
Oceanview
$1,789
Balcony
$2,059
Suite
$6,814
From
US$1,449
Per Person
View Trip
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