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MSC Cruises from Florence

Start your journey from Florence with 7 unique MSC cruise itineraries to choose from. April, October and November are the most popular months to begin your cruise from Florence and MSC Cruises have 65 trips departing this season.
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7 Cruises (65 Cruise Departures)
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Mar 2026 to Apr 2026
Visit: Italy, Spain, France
Inside
$1,154
Oceanview
$746
Balcony
$935
Suite
-
From
US$746
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Apr 2027 to Nov 2027
Visit: Italy, France, Spain, Sardinia
Inside
$806
Oceanview
$916
Balcony
$1,006
Suite
$1,726
From
US$806
Per Person
View Trip
9 Day Mediterranean with MSC Cruises
Cruise

9 Days (8 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 27 April 2026
Visit: Italy, Sardinia, Sicily, Malta, Spain, France
Inside
-
Oceanview
-
Balcony
$1,592
Suite
-
From
US$1,592
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Florence to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 10 November 2026
Visit: Italy, Sardinia, Sicily, Malta (+6 more), Spain, Gibraltar, Morocco, Brazil, Uruguay, Argentina
Exclusive Savings
Inside
-
Oceanview
$2,512
Balcony
$2,764
Suite
$4,132
From
US$2,512
Save 57
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Florence to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 14 November 2027
Visit: Italy, France, Spain, Brazil
Inside
$1,478
Oceanview
$1,818
Balcony
$2,088
Suite
$6,843
From
US$1,478
Per Person
View Trip
25 Day Msc Grand Voyages with MSC Cruises
Cruise

25 Days (24 Nights) Florence to Miami
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 18 October 2026
Visit: Italy, France, Spain, Gibraltar, Morocco, Portugal, USA
Inside
$1,939
Oceanview
$2,289
Balcony
$2,561
Suite
$6,528
From
US$1,939
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Florence to Florence
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: May 2026 to Nov 2026
Visit: Italy, Sardinia, Sicily, Malta, Spain, France
Exclusive Savings
Inside
$884
Oceanview
$1,077
Balcony
$1,147
Suite
$1,455
From
US$884
Save 52
Per Person
View Trip
Results: 7 results

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