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MSC Cruises from Palermo

Start your journey from Palermo with 11 unique MSC cruise itineraries to choose from. October and November are the most popular months to begin your cruise from Palermo and MSC Cruises have 227 trips departing this season.
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Duration
8 Days
27 Days
Price
$600pp
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11 Cruises (227 Cruise Departures)
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Apr 2027 to Oct 2027
Visit: Sicily, Spain, France, Italy
Bonus Onboard Credit
Inside
$820
Oceanview
$920
Balcony
$1,100
Suite
-
From
US$820
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Apr 2027 to Jan 2028
Visit: Sicily, Malta, Spain, France, Italy
Bonus Onboard Credit
Inside
$791
Oceanview
$951
Balcony
$1,081
Suite
$1,601
From
US$791
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ships: MSC Euribia, MSC Splendida
Departures: Feb 2026 to Mar 2028
Visit: Sicily, Tunisia, Spain, France, Italy
Bonus Onboard Credit
Inside
$660
Oceanview
$951
Balcony
$762
Suite
$1,372
From
US$660
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Palermo to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 12 November 2026
Visit: Sicily, Malta, Spain, Gibraltar (+4 more), Morocco, Brazil, Uruguay, Argentina
Bonus Onboard Credit
Inside
$1,911
Oceanview
$2,347
Balcony
$2,531
Suite
$4,122
From
US$1,911
Per Person
View Trip
27 Day Mediterranean with MSC Cruises
Cruise

27 Days (26 Nights) Palermo to Miami
Cruise Line: MSC Cruises
Ship: MSC Meraviglia
Departure: 16 October 2026
Visit: Sicily, Italy, France, Spain (+4 more), Gibraltar, Morocco, Portugal, USA
Bonus Onboard Credit
Inside
$2,072
Oceanview
$2,403
Balcony
$3,125
Suite
$7,082
From
US$2,072
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2026 to Nov 2026
Visit: Sicily, Spain, France, Italy
Bonus Onboard Credit
Inside
$940
Oceanview
$1,040
Balcony
$1,210
Suite
$1,690
From
US$940
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ships: MSC Meraviglia, MSC Virtuosa
Departures: May 2026 to Nov 2027
Visit: Sicily, Italy, France, Spain, Tunisia
Bonus Onboard Credit
Drinks, WiFi & Onboard Credit
Exclusive Savings
Inside
$967
Oceanview
$989
Balcony
$1,149
Suite
$2,314
From
US$967
Save 72
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 04 November 2027
Visit: Sicily, Malta, Spain, France, Italy
Bonus Onboard Credit
Inside
$1,039
Oceanview
$1,199
Balcony
$1,329
Suite
$1,849
From
US$1,039
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departures: May 2026 to Nov 2026
Visit: Sicily, Malta, Spain, France, Italy, Sardinia
Bonus Onboard Credit
Inside
$865
Oceanview
$1,041
Balcony
$1,110
Suite
$1,675
From
US$865
Per Person
View Trip
9 Day Mediterranean with MSC Cruises
Cruise

9 Days (8 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Splendida
Departure: 29 April 2026
Visit: Sicily, Malta, Spain, France, Italy, Sardinia
Bonus Onboard Credit
Inside
$1,049
Oceanview
$1,179
Balcony
$1,239
Suite
$1,819
From
US$1,049
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise

23 Days (22 Nights) Palermo to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 12 November 2027
Visit: Sicily, Italy, France, Spain, Brazil
Drinks, WiFi & Onboard Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$8,335
From
US$8,335
Save 240
Per Person
View Trip
Results: 11 results

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