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MSC Cruises from Orlando

Start your journey from Orlando with 41 unique MSC cruise itineraries to choose from. January, February and March are the most popular months to begin your cruise from Orlando and MSC Cruises have 353 trips departing this season.
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15 Days
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41 Cruises (353 Cruise Departures)
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Jan 2027 to Feb 2027
Visit: USA, Bahamas
Bonus Onboard Credit
Inside
$291
Oceanview
$351
Balcony
$411
Suite
$761
From
US$291
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 19 April 2026
Visit: USA, Bahamas, Mexico
Bonus Onboard Credit
Inside
$1,038
Oceanview
$1,228
Balcony
$1,378
Suite
$2,228
From
US$1,038
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Feb 2026 to Mar 2026
Visit: USA, Mexico, Cayman Islands, Jamaica, Bahamas
Bonus Onboard Credit
Inside
$540
Oceanview
$688
Balcony
$848
Suite
$1,780
From
US$540
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 22 November 2026
Visit: USA, Bahamas, Jamaica, Cayman Islands
Bonus Onboard Credit
Inside
$908
Oceanview
$1,098
Balcony
$1,318
Suite
$2,481
From
US$908
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 24 January 2026
Visit: USA, Bahamas, Puerto Rico, Dominican Republic
Bonus Onboard Credit
Inside
$914
Oceanview
-
Balcony
-
Suite
-
From
US$914
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Apr 2026 to Oct 2026
Visit: USA, Bahamas, Mexico
Bonus Onboard Credit
Inside
$808
Oceanview
$988
Balcony
$1,128
Suite
$1,908
From
US$808
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Jan 2026 to Jan 2028
Visit: USA, Bahamas
Bonus Onboard Credit
Inside
$238
Oceanview
$308
Balcony
$368
Suite
$721
From
US$238
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 20 December 2026
Visit: USA, Bahamas, Jamaica, Cayman Islands, Dominican Republic
Bonus Onboard Credit
Exclusive Savings
Inside
$2,082
Oceanview
$2,334
Balcony
$2,644
Suite
$3,537
From
US$2,082
Save 50
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visit: USA, Bahamas, Mexico
Bonus Onboard Credit
Inside
$565
Oceanview
$665
Balcony
$811
Suite
$1,511
From
US$565
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 31 January 2026
Visit: USA, Bahamas, Puerto Rico, Dominican Republic, Mexico, Cayman Islands, Jamaica
Bonus Onboard Credit
Inside
$1,010
Oceanview
$1,240
Balcony
$1,570
Suite
$3,672
From
US$1,010
Per Person
View Trip
6 Day Caribbean And Antilles with MSC Cruises
Cruise

6 Days (5 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 26 March 2026
Visit: USA, Bahamas, Turks and Caicos Islands
Bonus Onboard Credit
Inside
$462
Oceanview
$512
Balcony
$592
Suite
$1,212
From
US$462
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Feb 2026 to Mar 2026
Visit: USA, Bahamas, Dominican Republic, Mexico, Cayman Islands, Jamaica
Bonus Onboard Credit
Inside
$1,066
Oceanview
$1,286
Balcony
$1,616
Suite
-
From
US$1,066
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 27 December 2026
Visit: USA, Dominican Republic, Bahamas
Bonus Onboard Credit
Inside
$1,100
Oceanview
$1,220
Balcony
$1,390
Suite
$1,918
From
US$1,100
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise

4 Days (3 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Jan 2026 to Apr 2028
Visit: USA, Bahamas
Bonus Onboard Credit
Inside
$198
Oceanview
$258
Balcony
$308
Suite
$612
From
US$198
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Apr 2026 to Oct 2026
Visit: USA, Bahamas, Mexico
Bonus Onboard Credit
Inside
$519
Oceanview
$639
Balcony
$729
Suite
$1,319
From
US$519
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 04 April 2026
Visit: USA, Mexico, Belize, Bahamas
Bonus Onboard Credit
Inside
$601
Oceanview
$711
Balcony
$841
Suite
$3,510
From
US$601
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visit: USA, Bahamas, Dominican Republic, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$1,052
Oceanview
$1,252
Balcony
$1,552
Suite
$2,799
From
US$1,052
Save 57
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 28 February 2026
Visit: USA, Bahamas, Dominican Republic, Mexico, Cayman Islands, Jamaica
Bonus Onboard Credit
Inside
$1,128
Oceanview
$1,278
Balcony
$1,608
Suite
$6,094
From
US$1,128
Per Person
View Trip
5 Day Caribbean & Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: May 2026 to Feb 2028
Visit: USA, Bahamas
Bonus Onboard Credit
Inside
$281
Oceanview
$311
Balcony
$371
Suite
$782
From
US$281
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Feb 2026 to Mar 2026
Visit: USA, Mexico, Cayman Islands, Jamaica, Bahamas, Dominican Republic
Bonus Onboard Credit
Inside
$1,088
Oceanview
$1,308
Balcony
$1,638
Suite
$6,337
From
US$1,088
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 09 January 2026
Visit: USA, Mexico, Belize, Honduras
Bonus Onboard Credit
Inside
$490
Oceanview
$600
Balcony
$720
Suite
$1,569
From
US$490
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 04 April 2026
Visit: USA, Mexico, Belize, Bahamas, Dominican Republic
Bonus Onboard Credit
Inside
$1,282
Oceanview
$1,502
Balcony
$1,762
Suite
$4,361
From
US$1,282
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: May 2026 to Oct 2026
Visit: USA, Bahamas, Mexico
Bonus Onboard Credit
Inside
$828
Oceanview
$1,018
Balcony
$1,168
Suite
$2,044
From
US$828
Per Person
View Trip
5 Day Bahamas with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 01 February 2026
Visit: USA, Bahamas
Bonus Onboard Credit
Inside
$199
Oceanview
$329
Balcony
$339
Suite
$792
From
US$199
Per Person
View Trip
7 Day Caribbean And Antilles with MSC Cruises
Cruise

7 Days (6 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 18 January 2026
Visit: USA, Bahamas, Dominican Republic
Bonus Onboard Credit
Inside
$289
Oceanview
$399
Balcony
$519
Suite
$1,299
From
US$289
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Feb 2026 to Oct 2027
Visit: USA, Bahamas, Dominican Republic
Bonus Onboard Credit
Inside
$389
Oceanview
$499
Balcony
$639
Suite
$1,461
From
US$389
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Nov 2026 to Dec 2026
Visit: USA, Bahamas, Jamaica, Cayman Islands
Bonus Onboard Credit
Inside
$741
Oceanview
$881
Balcony
$991
Suite
$1,540
From
US$741
Per Person
View Trip
6 Day Caribbean And Antilles with MSC Cruises
Cruise

6 Days (5 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 28 December 2025
Visit: USA, Bahamas, Mexico
Bonus Onboard Credit
Inside
-
Oceanview
-
Balcony
$1,452
Suite
-
From
US$1,452
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 21 January 2026
Visit: USA, Bahamas
Bonus Onboard Credit
Inside
$225
Oceanview
$285
Balcony
$335
Suite
$758
From
US$225
Per Person
View Trip
6 Day Caribbean And Antilles with MSC Cruises
Cruise

6 Days (5 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 16 January 2026
Visit: USA, Turks and Caicos Islands, Bahamas
Bonus Onboard Credit
Inside
$317
Oceanview
$397
Balcony
$517
Suite
$1,162
From
US$317
Per Person
View Trip
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