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MSC Cruises from Orlando

Start your journey from Orlando with 46 unique MSC cruise itineraries to choose from. March and December are the most popular months to begin your cruise from Orlando and MSC Cruises have 360 trips departing this season.
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16 Days
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46 Cruises (360 Cruise Departures)
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 28 March 2026
Visit: USA, Bahamas, Dominican Republic, Mexico, Belize
Bonus Onboard Credit
Inside
$1,192
Oceanview
$1,412
Balcony
$1,712
Suite
$3,711
From
US$1,192
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 27 December 2026
Visit: USA, Dominican Republic, Bahamas
Bonus Onboard Credit
Inside
$1,428
Oceanview
$1,618
Balcony
$1,838
Suite
$2,985
From
US$1,428
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 14 March 2026
Visit: USA, Bahamas, Dominican Republic, Mexico, Cayman Islands, Jamaica
Bonus Onboard Credit
Inside
$1,176
Oceanview
$1,396
Balcony
$1,726
Suite
-
From
US$1,176
Per Person
View Trip
9 Day Caribbean And Antilles with MSC Cruises
Cruise

9 Days (8 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 06 November 2027
Visit: USA, Bahamas, Dominican Republic, Puerto Rico
Bonus Onboard Credit
Inside
$769
Oceanview
$889
Balcony
$1,069
Suite
$1,909
From
US$769
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Apr 2026 to Oct 2026
Visit: USA, Bahamas, Mexico
Bonus Onboard Credit
Inside
$808
Oceanview
$988
Balcony
$1,128
Suite
$1,908
From
US$808
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 28 February 2026
Visit: USA, Bahamas, Dominican Republic, Mexico, Cayman Islands, Jamaica
Bonus Onboard Credit
Inside
$1,128
Oceanview
$1,278
Balcony
$1,608
Suite
$7,472
From
US$1,128
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 December 2027
Visit: USA, Bahamas, Jamaica, Cayman Islands, Mexico
Bonus Onboard Credit
Inside
$1,488
Oceanview
$1,658
Balcony
$1,898
Suite
$2,975
From
US$1,488
Per Person
View Trip
5 Day Bahamas with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 01 February 2026
Visit: USA, Bahamas
Bonus Onboard Credit
Inside
-
Oceanview
-
Balcony
-
Suite
$992
From
US$992
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Nov 2026 to Dec 2026
Visit: USA, Bahamas, Jamaica, Cayman Islands
Bonus Onboard Credit
Inside
$740
Oceanview
$880
Balcony
$1,060
Suite
$1,809
From
US$740
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 December 2027
Visit: USA, Bahamas, Jamaica, Cayman Islands, Mexico
Bonus Onboard Credit
Inside
$1,227
Oceanview
$1,357
Balcony
$1,537
Suite
$2,294
From
US$1,227
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Feb 2026 to Oct 2027
Visit: USA, Bahamas, Dominican Republic
Bonus Onboard Credit
Inside
$379
Oceanview
$489
Balcony
$629
Suite
$1,377
From
US$379
Per Person
View Trip
5 Day Caribbean & Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: May 2026 to Feb 2028
Visit: USA, Bahamas
Bonus Onboard Credit
Free Balcony Upgrade
Inside
$251
Oceanview
$311
Balcony
$371
Suite
$782
From
US$251
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 18 November 2027
Visit: USA, Bahamas, Cayman Islands, Jamaica
Bonus Onboard Credit
Inside
$968
Oceanview
$1,108
Balcony
$1,348
Suite
$2,354
From
US$968
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Nov 2026 to Dec 2026
Visit: USA, Bahamas, Jamaica, Cayman Islands
Bonus Onboard Credit
Inside
$848
Oceanview
$1,008
Balcony
$1,198
Suite
$2,334
From
US$848
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise

4 Days (3 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Dec 2027 to Apr 2028
Visit: USA, Bahamas
Bonus Onboard Credit
Inside
$349
Oceanview
$389
Balcony
$449
Suite
$789
From
US$349
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 21 November 2027
Visit: USA, Bahamas, Cayman Islands, Jamaica
Bonus Onboard Credit
Inside
$697
Oceanview
$797
Balcony
$977
Suite
$1,707
From
US$697
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Feb 2026 to Mar 2028
Visit: USA, Bahamas
Bonus Onboard Credit
Inside
$199
Oceanview
$299
Balcony
$339
Suite
$792
From
US$199
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 04 April 2026
Visit: USA, Mexico, Belize, Bahamas
Bonus Onboard Credit
Inside
$579
Oceanview
$689
Balcony
$819
Suite
$1,571
From
US$579
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Jan 2027 to Feb 2027
Visit: USA, Bahamas
Bonus Onboard Credit
Inside
$293
Oceanview
$353
Balcony
$413
Suite
$763
From
US$293
Per Person
View Trip
13 Day Caribbean And Antilles with MSC Cruises
Cruise

13 Days (12 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 06 November 2027
Visit: USA, Bahamas, Dominican Republic, Puerto Rico
Bonus Onboard Credit
Inside
$1,033
Oceanview
$1,203
Balcony
$1,443
Suite
$2,641
From
US$1,033
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 23 December 2027
Visit: USA, Bahamas, Dominican Republic, Turks and Caicos Islands
Bonus Onboard Credit
Inside
$967
Oceanview
$1,097
Balcony
$1,277
Suite
$2,042
From
US$967
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Feb 2026 to Mar 2026
Visit: USA, Mexico, Cayman Islands, Jamaica, Bahamas
Bonus Onboard Credit
Inside
$508
Oceanview
$618
Balcony
$758
Suite
$3,066
From
US$508
Per Person
View Trip
16 Day Caribbean And Antilles with MSC Cruises
Cruise

16 Days (15 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 October 2027
Visit: USA, Bahamas, Mexico, Dominican Republic, Puerto Rico
Bonus Onboard Credit
Inside
$1,346
Oceanview
$1,566
Balcony
$1,926
Suite
$3,403
From
US$1,346
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visit: USA, Bahamas, Mexico, Dominican Republic
Bonus Onboard Credit
Inside
$1,092
Oceanview
$1,292
Balcony
$1,562
Suite
$2,838
From
US$1,092
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 21 November 2027
Visit: USA, Bahamas, Cayman Islands, Jamaica
Bonus Onboard Credit
Inside
$988
Oceanview
$1,138
Balcony
$1,378
Suite
$2,471
From
US$988
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 04 April 2026
Visit: USA, Mexico, Belize, Bahamas, Dominican Republic
Bonus Onboard Credit
Inside
$1,272
Oceanview
$1,492
Balcony
$1,752
Suite
$4,351
From
US$1,272
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visit: USA, Bahamas, Dominican Republic, Mexico
Bonus Onboard Credit
Exclusive Savings
Inside
$1,042
Oceanview
$1,242
Balcony
$1,542
Suite
$2,790
From
US$1,042
Save 57
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Feb 2026 to Mar 2026
Visit: USA, Bahamas
Bonus Onboard Credit
Inside
$279
Oceanview
$379
Balcony
$419
Suite
$812
From
US$279
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 20 December 2026
Visit: USA, Bahamas, Jamaica, Cayman Islands, Dominican Republic
Bonus Onboard Credit
Exclusive Savings
Inside
$2,072
Oceanview
$2,324
Balcony
$2,634
Suite
$3,527
From
US$2,072
Save 50
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 19 April 2026
Visit: USA, Bahamas, Mexico
Bonus Onboard Credit
Inside
$1,038
Oceanview
$1,228
Balcony
$1,378
Suite
$2,228
From
US$1,038
Per Person
View Trip
Results: 1-30 of 46

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