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MSC Cruises from Orlando

Start your journey from Orlando with 46 unique MSC cruise itineraries to choose from. January is the most popular month to begin your cruise from Orlando and MSC Cruises have 326 trips departing this season.
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15 Days
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46 Cruises (326 Cruise Departures)
5 Day Bahamas with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 01 February 2026
Visit: USA, Bahamas
Inside
$189
Oceanview
$299
Balcony
$339
Suite
$792
From
US$189
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 27 December 2026
Visit: USA, Dominican Republic, Bahamas
Inside
$1,428
Oceanview
$1,618
Balcony
$1,838
Suite
$2,985
From
US$1,428
Per Person
View Trip
9 Day Caribbean And Antilles with MSC Cruises
Cruise

9 Days (8 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 27 December 2025
Visit: USA, Bahamas, Mexico, Cayman Islands, Jamaica
Inside
$1,068
Oceanview
-
Balcony
-
Suite
$4,517
From
US$1,068
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visit: USA, Bahamas, Mexico
Inside
$565
Oceanview
$665
Balcony
$811
Suite
$1,511
From
US$565
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Feb 2026 to Mar 2026
Visit: USA, Bahamas, Dominican Republic, Mexico, Cayman Islands, Jamaica
Inside
$1,066
Oceanview
$1,286
Balcony
$1,616
Suite
-
From
US$1,066
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 27 December 2026
Visit: USA, Dominican Republic, Bahamas
Inside
$1,100
Oceanview
$1,220
Balcony
$1,390
Suite
$1,918
From
US$1,100
Per Person
View Trip
5 Day Caribbean & Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: May 2026 to Nov 2026
Visit: USA, Bahamas
Inside
$281
Oceanview
$311
Balcony
$371
Suite
$721
From
US$281
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Feb 2026 to Mar 2026
Visit: USA, Mexico, Cayman Islands, Jamaica, Bahamas, Dominican Republic
Inside
$1,088
Oceanview
$1,308
Balcony
$1,638
Suite
$6,337
From
US$1,088
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visit: USA, Bahamas, Mexico, Dominican Republic
Inside
$1,102
Oceanview
$1,302
Balcony
$1,572
Suite
$2,848
From
US$1,102
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Feb 2026 to Mar 2026
Visit: USA, Mexico, Cayman Islands, Jamaica, Bahamas
Inside
$519
Oceanview
$699
Balcony
$839
Suite
$1,699
From
US$519
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 09 January 2026
Visit: USA, Mexico, Belize, Honduras
Inside
$459
Oceanview
$569
Balcony
$689
Suite
$1,569
From
US$459
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Dec 2025 to Apr 2027
Visit: USA, Bahamas
Inside
$159
Oceanview
$209
Balcony
$288
Suite
$721
From
US$159
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 22 November 2026
Visit: USA, Bahamas, Jamaica, Cayman Islands
Inside
$908
Oceanview
$1,098
Balcony
$1,318
Suite
$2,481
From
US$908
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 24 January 2026
Visit: USA, Bahamas, Puerto Rico, Dominican Republic
Inside
$914
Oceanview
$1,064
Balcony
$1,394
Suite
$6,043
From
US$914
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise

4 Days (3 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Dec 2025 to Oct 2027
Visit: USA, Bahamas
Inside
$169
Oceanview
$229
Balcony
$279
Suite
$612
From
US$169
Per Person
View Trip
6 Day Caribbean And Antilles with MSC Cruises
Cruise

6 Days (5 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 26 March 2026
Visit: USA, Bahamas, Turks and Caicos Islands
Inside
$452
Oceanview
$512
Balcony
$592
Suite
$1,212
From
US$452
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Feb 2026 to Mar 2026
Visit: USA, Mexico, Cayman Islands, Jamaica, Bahamas, Dominican Republic
Inside
$1,046
Oceanview
$1,266
Balcony
$1,596
Suite
$4,307
From
US$1,046
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: May 2026 to Oct 2026
Visit: USA, Bahamas, Mexico
Inside
$828
Oceanview
$1,018
Balcony
$1,168
Suite
$2,044
From
US$828
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Dec 2026 to Oct 2027
Visit: USA, Bahamas
Inside
$281
Oceanview
$311
Balcony
$411
Suite
$721
From
US$281
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Jan 2027 to Feb 2027
Visit: USA, Bahamas
Inside
$291
Oceanview
$351
Balcony
$411
Suite
$761
From
US$291
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Jan 2026 to Mar 2026
Visit: USA, Bahamas
Inside
$159
Oceanview
$229
Balcony
$289
Suite
$792
From
US$159
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 21 December 2025
Visit: USA, Bahamas, Jamaica
Inside
-
Oceanview
-
Balcony
$919
Suite
$2,343
From
US$919
Per Person
View Trip
10 Day Caribbean And Antilles with MSC Cruises
Cruise

10 Days (9 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 16 January 2026
Visit: USA, Turks and Caicos Islands, Bahamas
Inside
$619
Oceanview
-
Balcony
-
Suite
-
From
US$619
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Feb 2026 to Oct 2027
Visit: USA, Bahamas, Dominican Republic
Inside
$427
Oceanview
$549
Balcony
$689
Suite
$1,461
From
US$427
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 02 January 2026
Visit: USA, Mexico, Belize, Honduras
Inside
$429
Oceanview
$539
Balcony
$659
Suite
$1,529
From
US$429
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Apr 2026 to Oct 2026
Visit: USA, Bahamas, Mexico
Inside
$808
Oceanview
$988
Balcony
$1,128
Suite
$1,908
From
US$808
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Nov 2026 to Dec 2026
Visit: USA, Bahamas, Jamaica, Cayman Islands
Inside
$888
Oceanview
$1,078
Balcony
$1,288
Suite
$2,334
From
US$888
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 31 January 2026
Visit: USA, Bahamas, Puerto Rico, Dominican Republic, Mexico, Cayman Islands, Jamaica
Inside
-
Oceanview
$1,240
Balcony
$1,570
Suite
$3,672
From
US$1,240
Per Person
View Trip
6 Day Caribbean And Antilles with MSC Cruises
Cruise

6 Days (5 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 16 January 2026
Visit: USA, Turks and Caicos Islands, Bahamas
Inside
$299
Oceanview
$379
Balcony
$499
Suite
$1,162
From
US$299
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Jan 2026 to Mar 2026
Visit: USA, Bahamas
Inside
$159
Oceanview
$239
Balcony
$279
Suite
$749
From
US$159
Per Person
View Trip
Results: 1-30 of 46

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