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MSC Cruises from Orlando

Start your journey from Orlando with 32 unique MSC cruise itineraries to choose from. December is the most popular month to begin your cruise from Orlando and MSC Cruises have 307 trips departing this season.
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16 Days
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32 Cruises (307 Cruise Departures)
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 21 November 2027
Visit: USA, Bahamas, Cayman Islands, Jamaica
Inside
$691
Oceanview
$791
Balcony
$971
Suite
$1,701
From
US$691
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Jun 2026 to Apr 2028
Visit: USA, Bahamas
Drinks & WiFi Package
Inside
$249
Oceanview
$299
Balcony
$349
Suite
$618
From
US$249
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 18 November 2027
Visit: USA, Bahamas, Cayman Islands, Jamaica
Inside
$997
Oceanview
$1,129
Balcony
$1,357
Suite
$2,416
From
US$997
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 December 2027
Visit: USA, Bahamas, Jamaica, Cayman Islands, Mexico
Inside
$1,221
Oceanview
$1,351
Balcony
$1,531
Suite
$2,351
From
US$1,221
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visit: USA, Bahamas, Dominican Republic, Mexico
Inside
$786
Oceanview
$1,026
Balcony
$1,436
Suite
$2,980
From
US$786
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Dec 2027 to Apr 2028
Visit: USA, Bahamas
Inside
$364
Oceanview
$416
Balcony
$464
Suite
$793
From
US$364
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 December 2027
Visit: USA, Bahamas, Dominican Republic, Turks and Caicos Islands
Inside
$1,284
Oceanview
$1,456
Balcony
$1,696
Suite
$2,923
From
US$1,284
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 21 November 2027
Visit: USA, Bahamas, Cayman Islands, Jamaica
Inside
$1,014
Oceanview
$1,156
Balcony
$1,396
Suite
$2,533
From
US$1,014
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 13 January 2028
Visit: USA, Bahamas
Inside
$364
Oceanview
$416
Balcony
$464
Suite
$793
From
US$364
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 23 December 2027
Visit: USA, Bahamas, Dominican Republic, Turks and Caicos Islands, Jamaica, Cayman Islands, Mexico
Inside
$2,190
Oceanview
$2,430
Balcony
$2,790
Suite
$4,430
From
US$2,190
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 05 March 2028
Visit: USA, Bahamas
Inside
$491
Oceanview
$553
Balcony
$613
Suite
$1,020
From
US$491
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 December 2027
Visit: USA, Bahamas, Jamaica, Cayman Islands, Mexico
Inside
$1,517
Oceanview
$1,679
Balcony
$1,907
Suite
$3,056
From
US$1,517
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visit: USA, Bahamas, Mexico, Dominican Republic
Inside
$776
Oceanview
$1,016
Balcony
$1,396
Suite
$2,960
From
US$776
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visit: USA, Bahamas, Mexico
Inside
$379
Oceanview
$499
Balcony
$669
Suite
$1,511
From
US$379
Per Person
View Trip
13 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

13 Days (12 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 06 November 2027
Visit: USA, Bahamas, Dominican Republic, Puerto Rico
Inside
$1,064
Oceanview
$1,226
Balcony
$1,466
Suite
$2,713
From
US$1,064
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visit: USA, Bahamas, Dominican Republic
Inside
$399
Oceanview
$519
Balcony
$709
Suite
$1,461
From
US$399
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 23 December 2027
Visit: USA, Bahamas, Dominican Republic, Turks and Caicos Islands
Inside
$961
Oceanview
$1,091
Balcony
$1,271
Suite
$2,091
From
US$961
Per Person
View Trip
9 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 06 November 2027
Visit: USA, Bahamas, Dominican Republic, Puerto Rico
Inside
$768
Oceanview
$888
Balcony
$1,068
Suite
$1,908
From
US$768
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Dec 2026 to Apr 2028
Visit: USA, Bahamas
Inside
$293
Oceanview
$353
Balcony
$413
Suite
$763
From
US$293
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Nov 2026 to Jan 2028
Visit: USA, Bahamas
Inside
$245
Oceanview
$305
Balcony
$365
Suite
$717
From
US$245
Per Person
View Trip
5 Day Caribbean & Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Jun 2026 to Feb 2028
Visit: USA, Bahamas
Inside
$299
Oceanview
$349
Balcony
$429
Suite
$872
From
US$299
Per Person
View Trip
16 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 October 2027
Visit: USA, Bahamas, Mexico, Dominican Republic, Puerto Rico
Inside
$1,829
Oceanview
$2,129
Balcony
$2,699
Suite
$5,099
From
US$1,829
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Jun 2026 to Oct 2026
Visit: USA, Bahamas, Mexico
Inside
$712
Oceanview
$897
Balcony
$1,052
Suite
$2,168
From
US$712
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 27 December 2026
Visit: USA, Dominican Republic, Bahamas
Inside
$998
Oceanview
$1,118
Balcony
$1,298
Suite
$2,079
From
US$998
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Jun 2026 to Oct 2026
Visit: USA, Bahamas, Mexico
Inside
$439
Oceanview
$588
Balcony
$649
Suite
$1,411
From
US$439
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Nov 2026 to Dec 2026
Visit: USA, Bahamas, Jamaica, Cayman Islands
Inside
$869
Oceanview
-
Balcony
$1,168
Suite
$1,579
From
US$869
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 20 December 2026
Visit: USA, Bahamas, Jamaica, Cayman Islands, Dominican Republic
Inside
$2,004
Oceanview
$2,284
Balcony
$2,664
Suite
$4,536
From
US$2,004
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Jan 2027 to Feb 2027
Visit: USA, Bahamas
Inside
$293
Oceanview
$353
Balcony
$413
Suite
$763
From
US$293
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Nov 2026 to Dec 2026
Visit: USA, Bahamas, Jamaica, Cayman Islands
Inside
$1,021
Oceanview
$1,191
Balcony
$1,421
Suite
$5,741
From
US$1,021
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 22 November 2026
Visit: USA, Bahamas, Jamaica, Cayman Islands
Inside
$1,053
Oceanview
$1,233
Balcony
$1,473
Suite
$2,801
From
US$1,053
Per Person
View Trip
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