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MSC Cruises from Orlando

Start your journey from Orlando with 32 unique MSC cruise itineraries to choose from. December is the most popular month to begin your cruise from Orlando and MSC Cruises have 343 trips departing this season.
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32 Cruises (343 Departures)
32 Cruises (343 Departures)
Departures
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Duration
4 Days
16 Days
Price
$300pp
$3,705pp
Countries
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4 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Jun 2026 to May 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$340
Oceanview
$479
Balcony
$548
Suite
$1,014
From (Per Person)
A$340
Per Person
View Trip
16 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 October 2027
Visits: USA, Bahamas, Mexico, Dominican Republic, Puerto Rico
Exclusive Savings
Inside
$2,547
Oceanview
$2,854
Balcony
$3,398
Suite
$5,764
From (Per Person)
A$2,547
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 18 November 2027
Visits: USA, Bahamas, Cayman Islands, Jamaica
Exclusive Savings
Inside
$1,877
Oceanview
$2,084
Balcony
$2,421
Suite
$4,015
From (Per Person)
A$1,877
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visits: USA, Bahamas, Dominican Republic, Mexico
Exclusive Savings
Inside
$1,538
Oceanview
$1,894
Balcony
$2,429
Suite
$5,062
From (Per Person)
A$1,538
Save 24
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 21 November 2027
Visits: USA, Bahamas, Cayman Islands, Jamaica
Exclusive Savings
Inside
$1,909
Oceanview
$2,137
Balcony
$2,484
Suite
$4,206
From (Per Person)
A$1,909
Per Person
View Trip
9 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 06 November 2027
Visits: USA, Bahamas, Dominican Republic, Puerto Rico
Exclusive Savings
Inside
$1,363
Oceanview
$1,531
Balcony
$1,818
Suite
$3,076
From (Per Person)
A$1,363
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 23 December 2027
Visits: USA, Bahamas, Dominican Republic, Turks and Caicos Islands, Jamaica, Cayman Islands, Mexico
Exclusive Savings
Inside
$3,676
Oceanview
$4,033
Balcony
$4,587
Suite
$7,042
From (Per Person)
A$3,676
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Dec 2027 to Sep 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$516
Oceanview
$595
Balcony
$664
Suite
$1,129
From (Per Person)
A$516
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 13 January 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$615
Oceanview
$694
Balcony
$773
Suite
$1,258
From (Per Person)
A$615
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visits: USA, Bahamas, Mexico, Dominican Republic
Exclusive Savings
Inside
$1,518
Oceanview
$1,874
Balcony
$2,409
Suite
$5,062
From (Per Person)
A$1,518
Save 24
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visits: USA, Bahamas, Mexico
Exclusive Savings
Inside
$715
Oceanview
$893
Balcony
$1,160
Suite
$2,536
From (Per Person)
A$715
Save 12
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visits: USA, Bahamas, Dominican Republic
Exclusive Savings
Inside
$655
Oceanview
$834
Balcony
$1,101
Suite
$2,477
From (Per Person)
A$655
Save 10
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Dec 2026 to Apr 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$523
Oceanview
$612
Balcony
$701
Suite
$1,245
From (Per Person)
A$523
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 21 November 2027
Visits: USA, Bahamas, Cayman Islands, Jamaica
Exclusive Savings
Inside
$1,220
Oceanview
$1,378
Balcony
$1,635
Suite
$2,744
From (Per Person)
A$1,220
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 December 2027
Visits: USA, Bahamas, Jamaica, Cayman Islands, Mexico
Exclusive Savings
Inside
$2,022
Oceanview
$2,210
Balcony
$2,487
Suite
$3,714
From (Per Person)
A$2,022
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 05 March 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$826
Oceanview
$925
Balcony
$1,014
Suite
$1,628
From (Per Person)
A$826
Per Person
View Trip
13 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

13 Days (12 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 06 November 2027
Visits: USA, Bahamas, Dominican Republic, Puerto Rico
Exclusive Savings
Inside
$2,063
Oceanview
$2,301
Balcony
$2,677
Suite
$4,548
From (Per Person)
A$2,063
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 December 2027
Visits: USA, Bahamas, Dominican Republic, Turks and Caicos Islands
Exclusive Savings
Inside
$2,325
Oceanview
$2,583
Balcony
$2,949
Suite
$4,790
From (Per Person)
A$2,325
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 23 December 2027
Visits: USA, Bahamas, Dominican Republic, Turks and Caicos Islands
Exclusive Savings
Inside
$1,635
Oceanview
$1,824
Balcony
$2,101
Suite
$3,328
From (Per Person)
A$1,635
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Nov 2026 to Jan 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$453
Oceanview
$552
Balcony
$642
Suite
$1,206
From (Per Person)
A$453
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 December 2027
Visits: USA, Bahamas, Jamaica, Cayman Islands, Mexico
Exclusive Savings
Inside
$2,669
Oceanview
$2,906
Balcony
$3,263
Suite
$4,975
From (Per Person)
A$2,669
Per Person
View Trip
5 Day Caribbean & Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Jul 2026 to Sep 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$483
Oceanview
$602
Balcony
$760
Suite
$1,360
From (Per Person)
A$483
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 20 December 2026
Visits: USA, Bahamas, Jamaica, Cayman Islands, Dominican Republic
Exclusive Savings
Inside
$3,448
Oceanview
$3,686
Balcony
$4,221
Suite
-
From (Per Person)
A$3,448
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 27 December 2026
Visits: USA, Dominican Republic, Bahamas
Exclusive Savings
Inside
$1,794
Oceanview
$1,972
Balcony
$2,239
Suite
$3,378
From (Per Person)
A$1,794
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Nov 2026 to Dec 2026
Visits: USA, Bahamas, Jamaica, Cayman Islands
Exclusive Savings
Inside
$1,309
Oceanview
$1,487
Balcony
$1,754
Suite
$3,051
From (Per Person)
A$1,309
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 22 November 2026
Visits: USA, Bahamas, Jamaica, Cayman Islands
Exclusive Savings
Inside
$1,871
Oceanview
$2,138
Balcony
$2,495
Suite
$4,603
From (Per Person)
A$1,871
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Nov 2026 to Dec 2026
Visits: USA, Bahamas, Jamaica, Cayman Islands
Exclusive Savings
Inside
$1,797
Oceanview
$2,055
Balcony
$2,391
Suite
$8,600
From (Per Person)
A$1,797
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 27 December 2026
Visits: USA, Dominican Republic, Bahamas
Exclusive Savings
Inside
$2,435
Oceanview
$2,603
Balcony
$2,960
Suite
$5,336
From (Per Person)
A$2,435
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Jul 2026 to Oct 2026
Visits: USA, Bahamas, Mexico
Exclusive Savings
Inside
$1,164
Oceanview
$1,560
Balcony
$1,906
Suite
$4,233
From (Per Person)
A$1,164
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Jul 2026 to Oct 2026
Visits: USA, Bahamas, Mexico
Exclusive Savings
Inside
$1,336
Oceanview
$1,683
Balcony
$2,118
Suite
$4,494
From (Per Person)
A$1,336
Per Person
View Trip
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