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MSC Cruises from Orlando

Start your journey from Orlando with 40 unique MSC cruise itineraries to choose from. December is the most popular month to begin your cruise from Orlando and MSC Cruises have 335 trips departing this season.
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40 Cruises (335 Cruise Departures)
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Apr 2026 to Oct 2026
Visit: USA, Bahamas, Mexico
Inside
$398
Oceanview
$568
Balcony
$598
Suite
$1,319
From
US$398
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Dec 2027 to Apr 2028
Visit: USA, Bahamas
Inside
$363
Oceanview
$403
Balcony
$473
Suite
$813
From
US$363
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 December 2027
Visit: USA, Bahamas, Dominican Republic, Turks and Caicos Islands
Inside
$1,303
Oceanview
$1,463
Balcony
$1,723
Suite
$2,893
From
US$1,303
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 18 November 2027
Visit: USA, Bahamas, Cayman Islands, Jamaica
Inside
$1,016
Oceanview
$1,136
Balcony
$1,396
Suite
$2,400
From
US$1,016
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 27 December 2026
Visit: USA, Dominican Republic, Bahamas
Inside
$1,098
Oceanview
$1,218
Balcony
$1,398
Suite
$2,285
From
US$1,098
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 05 March 2028
Visit: USA, Bahamas
Inside
$490
Oceanview
$540
Balcony
$610
Suite
$1,040
From
US$490
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 23 December 2027
Visit: USA, Bahamas, Dominican Republic, Turks and Caicos Islands, Jamaica, Cayman Islands, Mexico
Exclusive Savings
Inside
$2,177
Oceanview
$2,409
Balcony
$2,778
Suite
$4,369
From
US$2,177
Save 53
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Mar 2026 to Oct 2027
Visit: USA, Bahamas, Dominican Republic
Drinks & WiFi Package
Inside
$459
Oceanview
$579
Balcony
$679
Suite
$1,407
From
US$459
Per Person
View Trip
5 Day Caribbean & Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: May 2026 to Feb 2028
Visit: USA, Bahamas
Inside
$289
Oceanview
$379
Balcony
$379
Suite
$802
From
US$289
Per Person
View Trip
13 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

13 Days (12 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 06 November 2027
Visit: USA, Bahamas, Dominican Republic, Puerto Rico
Inside
$1,353
Oceanview
$1,553
Balcony
$1,893
Suite
$3,543
From
US$1,353
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 21 March 2026
Visit: USA, Mexico, Cayman Islands, Jamaica, Bahamas
Inside
$590
Oceanview
$700
Balcony
$860
Suite
-
From
US$590
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 13 January 2028
Visit: USA, Bahamas
Inside
$363
Oceanview
$403
Balcony
$473
Suite
$813
From
US$363
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 19 April 2026
Visit: USA, Bahamas, Mexico
Inside
$1,058
Oceanview
$1,248
Balcony
$1,408
Suite
$2,258
From
US$1,058
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visit: USA, Bahamas, Dominican Republic, Mexico
Inside
$1,083
Oceanview
$1,330
Balcony
$1,620
Suite
$2,943
From
US$1,083
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Dec 2026 to Apr 2028
Visit: USA, Bahamas
Inside
$283
Oceanview
$343
Balcony
$413
Suite
$743
From
US$283
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 04 April 2026
Visit: USA, Mexico, Belize, Bahamas, Dominican Republic
Inside
$1,103
Oceanview
$1,303
Balcony
$1,573
Suite
$4,175
From
US$1,103
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visit: USA, Bahamas, Mexico, Dominican Republic
Inside
$1,028
Oceanview
$1,330
Balcony
$1,620
Suite
$2,943
From
US$1,028
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: Apr 2026 to Oct 2026
Visit: USA, Bahamas, Mexico
Inside
$848
Oceanview
$1,028
Balcony
$1,178
Suite
$2,005
From
US$848
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 28 March 2026
Visit: USA, Bahamas, Dominican Republic, Mexico, Belize
Inside
$1,088
Oceanview
$1,378
Balcony
$1,688
Suite
-
From
US$1,088
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 23 December 2027
Visit: USA, Bahamas, Dominican Republic, Turks and Caicos Islands
Inside
$981
Oceanview
$1,111
Balcony
$1,301
Suite
$2,065
From
US$981
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 21 November 2027
Visit: USA, Bahamas, Cayman Islands, Jamaica
Inside
$1,033
Oceanview
$1,163
Balcony
$1,423
Suite
$2,515
From
US$1,033
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Apr 2026 to Apr 2028
Visit: USA, Bahamas
Drinks & WiFi Package
Inside
$258
Oceanview
$328
Balcony
$328
Suite
$618
From
US$258
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departures: May 2026 to Oct 2026
Visit: USA, Bahamas, Mexico
Inside
$838
Oceanview
$1,048
Balcony
$1,188
Suite
$2,093
From
US$838
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 22 March 2026
Visit: USA, Bahamas
Inside
$459
Oceanview
$539
Balcony
$599
Suite
$992
From
US$459
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Seashore
Departure: 22 November 2026
Visit: USA, Bahamas, Jamaica, Cayman Islands
Inside
$898
Oceanview
$1,068
Balcony
$1,278
Suite
$2,529
From
US$898
Per Person
View Trip
16 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 October 2027
Visit: USA, Bahamas, Mexico, Dominican Republic, Puerto Rico
Inside
$1,399
Oceanview
$1,599
Balcony
$1,979
Suite
$3,455
From
US$1,399
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Apr 2026 to Jan 2028
Visit: USA, Bahamas
Inside
$259
Oceanview
$319
Balcony
$349
Suite
$722
From
US$259
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 December 2027
Visit: USA, Bahamas, Jamaica, Cayman Islands, Mexico
Inside
$1,536
Oceanview
$1,686
Balcony
$1,946
Suite
$3,021
From
US$1,536
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 December 2027
Visit: USA, Bahamas, Jamaica, Cayman Islands, Mexico
Inside
$1,241
Oceanview
$1,371
Balcony
$1,561
Suite
$2,317
From
US$1,241
Per Person
View Trip
9 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Orlando to Orlando
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 06 November 2027
Visit: USA, Bahamas, Dominican Republic, Puerto Rico
Inside
$788
Oceanview
$908
Balcony
$1,098
Suite
$1,938
From
US$788
Per Person
View Trip
Results: 1-30 of 40

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