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MSC Cruises from Orlando

Start your journey from Orlando with 50 unique MSC cruise itineraries to choose from. December is the most popular month to begin your cruise from Orlando and MSC Cruises have 415 trips departing this season.
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50 Cruises (415 Departures)
50 Cruises (415 Departures)
Departures
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Duration
4 Days
16 Days
Price
$300pp
$5,009pp
Countries
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11 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departure: 18 November 2027
Visits: USA, Bahamas, Cayman Islands, Jamaica
Exclusive Savings
Inside
$1,877
Oceanview
$2,084
Balcony
$2,421
Suite
$4,015
From (Per Person)
A$1,877
Per Person
View Trip
13 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

13 Days (12 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departure: 06 November 2027
Visits: USA, Bahamas, Dominican Republic, Puerto Rico
Exclusive Savings
Inside
$2,063
Oceanview
$2,301
Balcony
$2,677
Suite
$4,548
From (Per Person)
A$2,063
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visits: USA, Bahamas, Dominican Republic
Exclusive Savings
Inside
$764
Oceanview
$942
Balcony
$1,210
Suite
$2,477
From (Per Person)
A$764
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visits: USA, Bahamas, Mexico, Dominican Republic
Exclusive Savings
Inside
$1,647
Oceanview
$1,884
Balcony
$2,419
Suite
$4,983
From (Per Person)
A$1,647
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Operator: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Nov 2026 to Jan 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$434
Oceanview
$523
Balcony
$612
Suite
$1,236
From (Per Person)
A$434
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Operator: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Dec 2026 to Apr 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$523
Oceanview
$612
Balcony
$701
Suite
$1,216
From (Per Person)
A$523
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Orlando to Orlando
Operator: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Oct 2026 to May 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$380
Oceanview
$459
Balcony
$528
Suite
$1,004
From (Per Person)
A$380
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Operator: MSC Cruises
Ships: MSC Grandiosa, MSC World Atlantic
Departures: Nov 2026 to Nov 2027
Visits: USA, Bahamas, Mexico
Exclusive Savings
Inside
$744
Oceanview
$923
Balcony
$1,190
Suite
$2,507
From (Per Person)
A$744
Save 15
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departures: Dec 2027 to Sep 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$519
Oceanview
$598
Balcony
$667
Suite
$1,132
From (Per Person)
A$519
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 December 2027
Visits: USA, Bahamas, Jamaica, Cayman Islands, Mexico
Exclusive Savings
Inside
$2,022
Oceanview
$2,210
Balcony
$2,487
Suite
$3,714
From (Per Person)
A$2,022
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

12 Days (11 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departure: 21 November 2027
Visits: USA, Bahamas, Cayman Islands, Jamaica
Exclusive Savings
Inside
$1,920
Oceanview
$2,148
Balcony
$2,495
Suite
$4,217
From (Per Person)
A$1,920
Per Person
View Trip
4 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departure: 13 January 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$618
Oceanview
$697
Balcony
$776
Suite
$1,261
From (Per Person)
A$618
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departure: 21 November 2027
Visits: USA, Bahamas, Cayman Islands, Jamaica
Exclusive Savings
Inside
$1,220
Oceanview
$1,378
Balcony
$1,635
Suite
$2,744
From (Per Person)
A$1,220
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departure: 23 December 2027
Visits: USA, Bahamas, Dominican Republic, Turks and Caicos Islands
Exclusive Savings
Inside
$1,635
Oceanview
$1,824
Balcony
$2,101
Suite
$3,328
From (Per Person)
A$1,635
Per Person
View Trip
11 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

11 Days (10 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 December 2027
Visits: USA, Bahamas, Jamaica, Cayman Islands, Mexico
Exclusive Savings
Inside
$2,669
Oceanview
$2,906
Balcony
$3,263
Suite
$8,788
From (Per Person)
A$2,669
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

12 Days (11 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departure: 19 December 2027
Visits: USA, Bahamas, Dominican Republic, Turks and Caicos Islands
Exclusive Savings
Inside
$2,336
Oceanview
$2,594
Balcony
$2,960
Suite
$4,801
From (Per Person)
A$2,336
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departures: Nov 2026 to Oct 2027
Visits: USA, Bahamas, Dominican Republic, Mexico
Exclusive Savings
Inside
$1,657
Oceanview
$1,924
Balcony
$2,458
Suite
$5,013
From (Per Person)
A$1,657
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departure: 23 December 2027
Visits: USA, Bahamas, Dominican Republic, Turks and Caicos Islands, Jamaica, Cayman Islands, Mexico
Exclusive Savings
Inside
$3,676
Oceanview
$4,033
Balcony
$4,587
Suite
$9,814
From (Per Person)
A$3,676
Per Person
View Trip
5 Day Caribbean & Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Operator: MSC Cruises
Ships: MSC Grandiosa, MSC Seashore
Departures: Sep 2026 to Sep 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$503
Oceanview
$592
Balcony
$790
Suite
$1,364
From (Per Person)
A$503
Per Person
View Trip
16 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departure: 30 October 2027
Visits: USA, Bahamas, Mexico, Dominican Republic, Puerto Rico
Exclusive Savings
Inside
$2,562
Oceanview
$2,869
Balcony
$3,413
Suite
$5,779
From (Per Person)
A$2,562
Per Person
View Trip
9 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departure: 06 November 2027
Visits: USA, Bahamas, Dominican Republic, Puerto Rico
Exclusive Savings
Inside
$1,363
Oceanview
$1,531
Balcony
$1,818
Suite
$3,076
From (Per Person)
A$1,363
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Grandiosa
Departure: 05 March 2028
Visits: USA, Bahamas
Exclusive Savings
Inside
$830
Oceanview
$929
Balcony
$1,018
Suite
$1,632
From (Per Person)
A$830
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Seashore
Departure: 22 November 2026
Visits: USA, Bahamas, Jamaica, Cayman Islands
Exclusive Savings
Inside
$1,762
Oceanview
$2,029
Balcony
$2,386
Suite
$3,772
From (Per Person)
A$1,762
Per Person
View Trip
16 Day Caribbean And Antilles with MSC Cruises
Cruise

16 Days (15 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC World Atlantic
Departure: 18 December 2027
Visits: USA, Bahamas, Turks and Caicos Islands, Dominican Republic, Mexico
Exclusive Savings
Inside
$4,968
Oceanview
$5,651
Balcony
$6,076
Suite
-
From (Per Person)
A$4,968
Per Person
View Trip
5 Day Caribbean And Antilles with MSC Cruises
Cruise

5 Days (4 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Seashore
Departures: Jan 2027 to Feb 2027
Visits: USA, Bahamas
Exclusive Savings
Inside
$463
Oceanview
$552
Balcony
$642
Suite
$1,255
From (Per Person)
A$463
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC World Atlantic
Departure: 27 November 2027
Visits: USA, Bahamas, Mexico, Turks and Caicos Islands, Dominican Republic
Exclusive Savings
Inside
$3,082
Oceanview
$3,696
Balcony
$3,973
Suite
$7,240
From (Per Person)
A$3,082
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC World Atlantic
Departure: 13 November 2027
Visits: USA, Bahamas, Mexico, Turks and Caicos Islands, Dominican Republic
Exclusive Savings
Inside
$3,785
Oceanview
$4,528
Balcony
$4,676
Suite
$8,488
From (Per Person)
A$3,785
Per Person
View Trip
15 Day Caribbean And Antilles with MSC Cruises
Cruise

15 Days (14 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC World Atlantic
Departures: Jan 2028 to Oct 2028
Visits: USA, Bahamas, Mexico, Turks and Caicos Islands, Dominican Republic
Exclusive Savings
Inside
$2,617
Oceanview
$3,171
Balcony
$3,646
Suite
$6,498
From (Per Person)
A$2,617
Per Person
View Trip
12 Day Caribbean And Antilles with MSC Cruises
Cruise

12 Days (11 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC Seashore
Departure: 18 October 2026
Visits: USA, Bahamas, Mexico
Exclusive Savings
Inside
$1,663
Oceanview
$1,881
Balcony
$2,297
Suite
-
From (Per Person)
A$1,663
Per Person
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Orlando to Orlando
Operator: MSC Cruises
Ship: MSC World Atlantic
Departure: 27 November 2027
Visits: USA, Bahamas, Mexico
Exclusive Savings
Inside
$1,507
Oceanview
$1,784
Balcony
$1,952
Suite
$3,427
From (Per Person)
A$1,507
Per Person
View Trip
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