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MSC Cruises from Santos

Start your journey from Santos with 30 unique MSC cruise itineraries to choose from. March is the most popular month to begin your cruise from Santos and MSC Cruises have 48 trips departing this season.
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30 Cruises (48 Departures)
30 Cruises (48 Departures)
Departures
Duration
2 Days
25 Days
Price
$200pp
$3,721pp
Countries
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18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Santos to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visits: Brazil, Spain, France, Italy
Exclusive Savings
Inside
-
Oceanview
$2,373
Balcony
$3,016
Suite
-
From (Per Person)
A$2,373
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 05 February 2027
Visits: Brazil
Exclusive Savings
Inside
$1,238
Oceanview
$1,396
Balcony
$1,525
Suite
$1,832
From (Per Person)
A$1,238
Per Person
View Trip
25 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

25 Days (24 Nights) Santos to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visits: Brazil, Cape Verde, Portugal, Morocco, Spain, France, Italy
Exclusive Savings
Inside
$3,491
Oceanview
$4,006
Balcony
$4,976
Suite
$8,303
From (Per Person)
A$3,491
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

19 Days (18 Nights) Santos to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visits: Brazil, Spain, Morocco, Italy
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,694
Suite
-
From (Per Person)
A$3,694
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

20 Days (19 Nights) Santos to Rome
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visits: Brazil, Spain, Morocco, Italy
Exclusive Savings
Inside
$2,470
Oceanview
$2,757
Balcony
$3,312
Suite
$5,520
From (Per Person)
A$2,470
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Feb 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,168
Suite
$1,604
From (Per Person)
A$852
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

24 Days (23 Nights) Santos to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visits: Brazil, Cape Verde, Portugal, Morocco, Spain, France, Italy
Exclusive Savings
Inside
$3,319
Oceanview
$3,834
Balcony
$4,774
Suite
$7,427
From (Per Person)
A$3,319
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Santos to Lisbon
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visits: Brazil, Cape Verde, Portugal
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,171
Suite
$4,844
From (Per Person)
A$3,171
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visits: Brazil, Spain, Morocco
Exclusive Savings
Inside
$2,200
Oceanview
$2,378
Balcony
$3,269
Suite
$6,229
From (Per Person)
A$2,200
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 05 December 2026
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,793
Oceanview
$1,961
Balcony
$2,357
Suite
$3,317
From (Per Person)
A$1,793
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

22 Days (21 Nights) Santos to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visits: Brazil, Spain, France, Italy, Sicily
Exclusive Savings
Inside
$2,994
Oceanview
$3,300
Balcony
$4,073
Suite
-
From (Per Person)
A$2,994
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

23 Days (22 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visits: Brazil, Cape Verde, Portugal, Morocco, Spain, France
Exclusive Savings
Inside
$3,176
Oceanview
$3,641
Balcony
$4,542
Suite
$7,086
From (Per Person)
A$3,176
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Santos to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visits: Brazil, Spain, France, Italy
Exclusive Savings
Inside
$2,041
Oceanview
$2,229
Balcony
$2,843
Suite
-
From (Per Person)
A$2,041
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visits: Brazil, Spain, France
Exclusive Savings
Inside
$1,889
Oceanview
$2,077
Balcony
$2,661
Suite
-
From (Per Person)
A$1,889
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

22 Days (21 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visits: Brazil, Cape Verde, Portugal, Morocco, Spain
Exclusive Savings
Inside
$3,013
Oceanview
$3,479
Balcony
$4,350
Suite
$6,805
From (Per Person)
A$3,013
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 16 November 2026
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
$951
Balcony
$1,158
Suite
-
From (Per Person)
A$951
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,109
Suite
-
From (Per Person)
A$852
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Feb 2027 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$861
Oceanview
$951
Balcony
$1,168
Suite
$1,653
From (Per Person)
A$861
Per Person
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 18 December 2026
Visits: Brazil
Exclusive Savings
Inside
$696
Oceanview
$795
Balcony
$914
Suite
$1,300
From (Per Person)
A$696
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,429
Oceanview
$1,676
Balcony
$1,963
Suite
$2,666
From (Per Person)
A$1,429
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Santos to Salvador
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
$1,033
Balcony
$1,182
Suite
$1,489
From (Per Person)
A$1,033
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visits: Brazil, Spain
Exclusive Savings
Inside
-
Oceanview
$1,973
Balcony
$2,528
Suite
-
From (Per Person)
A$1,973
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Santos to Rio de Janeiro
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica, MSC Virtuosa
Departures: Mar 2027 to Apr 2027
Visits: Brazil
Exclusive Savings
Inside
$253
Oceanview
$302
Balcony
$401
Suite
$669
From (Per Person)
A$253
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Santos to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visits: Brazil, Spain, Morocco, Tunisia, Sicily, Italy
Exclusive Savings
Inside
$3,162
Oceanview
$3,677
Balcony
-
Suite
-
From (Per Person)
A$3,162
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 26 December 2026
Visits: Brazil
Exclusive Savings
Inside
$2,617
Oceanview
-
Balcony
$2,864
Suite
$11,697
From (Per Person)
A$2,617
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visits: Brazil, Spain, Morocco, Tunisia, Sicily, Italy, France
Exclusive Savings
Inside
$3,487
Oceanview
$3,784
Balcony
-
Suite
$14,614
From (Per Person)
A$3,487
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visits: Brazil, Spain, Morocco
Exclusive Savings
Inside
$2,412
Oceanview
$2,808
Balcony
$3,214
Suite
$8,600
From (Per Person)
A$2,412
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Santos to Palermo
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visits: Brazil, Spain, Morocco, Tunisia, Sicily
Exclusive Savings
Inside
$2,979
Oceanview
$3,415
Balcony
-
Suite
-
From (Per Person)
A$2,979
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Jan 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,347
Suite
$2,079
From (Per Person)
A$1,347
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Salvador
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$2,705
From (Per Person)
A$2,705
Per Person
View Trip
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