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MSC Cruises from Santos

Start your journey from Santos with 29 unique MSC cruise itineraries to choose from. March and April are the most popular months to begin your cruise from Santos and MSC Cruises have 44 trips departing this season.
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25 Days
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29 Cruises (44 Cruise Departures)
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Santos to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France, Italy
Exclusive Savings
Inside
$2,148
Oceanview
$2,356
Balcony
$2,999
Suite
-
From
A$2,148
Per Person
View Trip
25 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

25 Days (24 Nights) Santos to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visit: Brazil, Cape Verde, Portugal, Morocco, Spain, France, Italy
Exclusive Savings
Inside
$3,735
Oceanview
$4,299
Balcony
$5,101
Suite
$8,279
From
A$3,735
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Santos to Rio de Janeiro
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica, MSC Virtuosa
Departures: Mar 2027 to Apr 2027
Visit: Brazil
Exclusive Savings
Inside
$252
Oceanview
$301
Balcony
$380
Suite
$668
From
A$252
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 16 November 2026
Visit: Brazil
Exclusive Savings
Inside
$861
Oceanview
$960
Balcony
$1,168
Suite
-
From
A$861
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

24 Days (23 Nights) Santos to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visit: Brazil, Cape Verde, Portugal, Morocco, Spain, France, Italy
Exclusive Savings
Inside
$3,563
Oceanview
$3,959
Balcony
$4,900
Suite
$7,404
From
A$3,563
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 05 December 2026
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,793
Oceanview
$2,070
Balcony
$2,367
Suite
$2,257
From
A$1,793
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visit: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,458
Oceanview
$1,706
Balcony
$1,963
Suite
$2,085
From
A$1,458
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 15 March 2027
Visit: Brazil
Exclusive Savings
Inside
$861
Oceanview
$960
Balcony
$1,119
Suite
-
From
A$861
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

22 Days (21 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visit: Brazil, Cape Verde, Portugal, Morocco, Spain
Exclusive Savings
Inside
$3,141
Oceanview
$3,606
Balcony
$4,477
Suite
$6,784
From
A$3,141
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

22 Days (21 Nights) Santos to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France, Italy, Sicily
Exclusive Savings
Inside
$2,973
Oceanview
$3,230
Balcony
$4,052
Suite
-
From
A$2,973
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visit: Brazil, Spain, Morocco, Gibraltar
Exclusive Savings
Inside
$2,184
Oceanview
$2,362
Balcony
$3,213
Suite
$6,213
From
A$2,184
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Santos to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France, Italy
Exclusive Savings
Inside
$2,025
Oceanview
$2,243
Balcony
$2,827
Suite
-
From
A$2,025
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain
Exclusive Savings
Inside
$1,791
Oceanview
$1,959
Balcony
$2,514
Suite
-
From
A$1,791
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Santos to Lisbon
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visit: Brazil, Cape Verde, Portugal
Exclusive Savings
Inside
$2,425
Oceanview
$2,751
Balcony
$3,276
Suite
$4,830
From
A$2,425
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Nov 2026 to Dec 2026
Visit: Brazil
Exclusive Savings
Inside
$861
Oceanview
$960
Balcony
$1,188
Suite
-
From
A$861
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visit: Brazil, Spain, France
Exclusive Savings
Inside
$1,874
Oceanview
$2,062
Balcony
$2,646
Suite
-
From
A$1,874
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Santos to Salvador
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visit: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,288
Suite
$1,486
From
A$1,288
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visit: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,311
Suite
-
From
A$1,311
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visit: Brazil
Exclusive Savings
Inside
$861
Oceanview
$960
Balcony
$1,119
Suite
-
From
A$861
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

20 Days (19 Nights) Santos to Rome
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visit: Brazil, Spain, Morocco, Gibraltar, Italy
Exclusive Savings
Inside
$2,362
Oceanview
$2,788
Balcony
$3,293
Suite
$5,501
From
A$2,362
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

23 Days (22 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visit: Brazil, Cape Verde, Portugal, Morocco, Spain, France
Exclusive Savings
Inside
$3,302
Oceanview
$3,916
Balcony
$4,669
Suite
$7,064
From
A$3,302
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco
Exclusive Savings
Inside
$2,514
Oceanview
$2,791
Balcony
$3,108
Suite
$8,583
From
A$2,514
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Salvador
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil
Drinks Package
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$2,697
From
A$2,697
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily, Italy, France
Exclusive Savings
Inside
$3,464
Oceanview
$3,761
Balcony
-
Suite
$17,855
From
A$3,464
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Jan 2027
Visit: Brazil
Exclusive Savings
Inside
-
Oceanview
$1,248
Balcony
$1,426
Suite
$2,079
From
A$1,248
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 26 December 2026
Visit: Brazil
Exclusive Savings
Inside
$2,627
Oceanview
$2,716
Balcony
$2,894
Suite
$18,162
From
A$2,627
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Santos to Palermo
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily
Exclusive Savings
Inside
$2,959
Oceanview
$3,395
Balcony
$4,029
Suite
$12,088
From
A$2,959
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Santos to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil, Spain, Morocco, Tunisia, Sicily, Italy
Exclusive Savings
Inside
$3,141
Oceanview
$3,448
Balcony
-
Suite
-
From
A$3,141
Per Person
View Trip
7 Day MSC Grand Voyages with MSC Cruises
Cruise

7 Days (6 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visit: Brazil
Drinks Package
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$3,952
From
A$3,952
Per Person
View Trip
Results: 29 results

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