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MSC Cruises from Santos

Start your journey from Santos with 26 unique MSC cruise itineraries to choose from. March and April are the most popular months to begin your cruise from Santos and MSC Cruises have 44 trips departing this season.
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26 Cruises (44 Departures)
26 Cruises (44 Departures)
Departures
Duration
2 Days
25 Days
Price
$200pp
$3,665pp
Countries
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5 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visits: Brazil
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$1,335
Suite
-
From (Per Person)
A$1,335
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

17 Days (16 Nights) Santos to Genoa
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visits: Brazil, Spain, France, Italy
Exclusive Savings
Inside
$2,041
Oceanview
$2,229
Balcony
$2,843
Suite
-
From (Per Person)
A$2,041
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 05 February 2027
Visits: Brazil
Exclusive Savings
Inside
$1,238
Oceanview
$1,396
Balcony
$1,525
Suite
$1,832
From (Per Person)
A$1,238
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

22 Days (21 Nights) Santos to Valencia
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visits: Brazil, Spain, France, Italy, Sicily
Exclusive Savings
Inside
-
Oceanview
$3,251
Balcony
$4,073
Suite
-
From (Per Person)
A$3,251
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departures: Dec 2026 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,109
Suite
-
From (Per Person)
A$852
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

18 Days (17 Nights) Santos to Rome
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visits: Brazil, Spain, France, Italy
Exclusive Savings
Inside
-
Oceanview
$2,373
Balcony
$3,016
Suite
-
From (Per Person)
A$2,373
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Santos to Lisbon
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visits: Brazil, Cape Verde, Portugal
Exclusive Savings
Inside
$2,330
Oceanview
-
Balcony
$3,290
Suite
$4,844
From (Per Person)
A$2,330
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

22 Days (21 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visits: Brazil, Cape Verde, Portugal, Morocco, Spain
Exclusive Savings
Inside
$3,162
Oceanview
$3,627
Balcony
$4,498
Suite
$6,805
From (Per Person)
A$3,162
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Feb 2027 to Mar 2027
Visits: Brazil
Exclusive Savings
Inside
$861
Oceanview
$951
Balcony
$1,168
Suite
$1,653
From (Per Person)
A$861
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

24 Days (23 Nights) Santos to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visits: Brazil, Cape Verde, Portugal, Morocco, Spain, France, Italy
Exclusive Savings
Inside
$3,467
Oceanview
$3,982
Balcony
$4,923
Suite
$7,427
From (Per Person)
A$3,467
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 16 November 2026
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,158
Suite
-
From (Per Person)
A$852
Per Person
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 05 December 2026
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,684
Oceanview
$1,961
Balcony
$2,347
Suite
$3,317
From (Per Person)
A$1,684
Per Person
View Trip
23 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

23 Days (22 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visits: Brazil, Cape Verde, Portugal, Morocco, Spain, France
Exclusive Savings
Inside
$3,324
Oceanview
$3,790
Balcony
$4,691
Suite
$7,086
From (Per Person)
A$3,324
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise
 (1)

5 Days (4 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica
Departures: Nov 2026 to Feb 2027
Visits: Brazil
Exclusive Savings
Inside
$852
Oceanview
$951
Balcony
$1,119
Suite
$1,604
From (Per Person)
A$852
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2026 to Feb 2027
Visits: Brazil, Uruguay, Argentina
Exclusive Savings
Inside
$1,429
Oceanview
$1,676
Balcony
$1,963
Suite
$2,666
From (Per Person)
A$1,429
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

15 Days (14 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visits: Brazil, Spain
Exclusive Savings
Inside
-
Oceanview
$1,973
Balcony
$2,528
Suite
-
From (Per Person)
A$1,973
Per Person
View Trip
25 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

25 Days (24 Nights) Santos to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 07 March 2027
Visits: Brazil, Cape Verde, Portugal, Morocco, Spain, France, Italy
Exclusive Savings
Inside
$3,640
Oceanview
$4,155
Balcony
$5,125
Suite
$8,303
From (Per Person)
A$3,640
Per Person
View Trip
2 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

2 Days (1 Nights) Santos to Rio de Janeiro
Cruise Line: MSC Cruises
Ships: MSC Divina, MSC Musica, MSC Virtuosa
Departures: Mar 2027 to Apr 2027
Visits: Brazil
Exclusive Savings
Inside
$253
Oceanview
$302
Balcony
$401
Suite
$669
From (Per Person)
A$253
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

16 Days (15 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Musica
Departure: 01 April 2027
Visits: Brazil, Spain, France
Exclusive Savings
Inside
$1,889
Oceanview
$2,077
Balcony
$2,661
Suite
-
From (Per Person)
A$1,889
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Santos to Salvador
Cruise Line: MSC Cruises
Ship: MSC Divina
Departure: 14 March 2027
Visits: Brazil
Exclusive Savings
Inside
$736
Oceanview
-
Balcony
$1,241
Suite
$1,489
From (Per Person)
A$736
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Santos to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visits: Brazil, Spain, Morocco
Exclusive Savings
Inside
$2,412
Oceanview
$2,808
Balcony
$3,125
Suite
$8,600
From (Per Person)
A$2,412
Per Person
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Santos to Maceio
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Dec 2026 to Jan 2027
Visits: Brazil
Exclusive Savings
Inside
$1,307
Oceanview
$1,248
Balcony
$1,347
Suite
$2,079
From (Per Person)
A$1,248
Per Person
View Trip
24 Day MSC Grand Voyages with MSC Cruises
Cruise

24 Days (23 Nights) Santos to Marseille
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visits: Brazil, Spain, Morocco, Tunisia, Sicily, Italy, France
Exclusive Savings
Inside
$3,259
Oceanview
$3,784
Balcony
-
Suite
$14,317
From (Per Person)
A$3,259
Per Person
View Trip
22 Day MSC Grand Voyages with MSC Cruises
Cruise

22 Days (21 Nights) Santos to Amalfi
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visits: Brazil, Spain, Morocco, Tunisia, Sicily, Italy
Exclusive Savings
Inside
$3,162
Oceanview
$3,677
Balcony
-
Suite
-
From (Per Person)
A$3,162
Per Person
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Santos to Santos
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 26 December 2026
Visits: Brazil
Exclusive Savings
Inside
$2,617
Oceanview
-
Balcony
$2,864
Suite
$18,162
From (Per Person)
A$2,617
Per Person
View Trip
21 Day MSC Grand Voyages with MSC Cruises
Cruise

21 Days (20 Nights) Santos to Palermo
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departure: 03 April 2027
Visits: Brazil, Spain, Morocco, Tunisia, Sicily
Exclusive Savings
Inside
$2,979
Oceanview
$3,415
Balcony
-
Suite
-
From (Per Person)
A$2,979
Per Person
View Trip
Results: 26 results

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