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MSC Opera

MSC Opera Cruises

Choose from 248 cruise vacations onboard the MSC Opera. Compare cruises ranging from 2 days to 26 days with departures available from February 2026 through to April 2028. Book with confidence supported by one of our dedicated expert CLIA cruise advisors.
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26 Days
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56 Cruises (248 Cruise Departures)
4 Day South Caribbean with MSC Cruises
Cruise

4 Days (3 Nights) La Romana to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 April 2027
Visit: Dominican Republic, Barbados
Inside
$209
Oceanview
$279
Balcony
$449
Suite
$719
From
US$209
Per Person
View Trip
6 Day South Africa with MSC Cruises
Cruise

6 Days (5 Nights) Cape Town to Cape Town
Cruise Line: MSC Cruises
Ships: MSC Armonia, MSC Opera
Departures: Apr 2026 to Mar 2027
Visit: South Africa, Namibia
Bonus Onboard Credit
Inside
$620
Oceanview
$675
Balcony
$774
Suite
$1,062
From
US$620
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Mar 2027 to Apr 2028
Visit: Dominican Republic, Virgin Islands, Saint Martin, Saint Kitts and Nevis, Antigua and Barbuda
Bonus Onboard Credit
Inside
$579
Oceanview
$799
Balcony
$1,289
Suite
$1,859
From
US$579
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Malaga to Malaga
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 06 May 2026
Visit: Spain, Gibraltar, Portugal, Sardinia, Italy, France
Bonus Onboard Credit
Inside
$1,611
Oceanview
-
Balcony
-
Suite
-
From
US$1,611
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Barcelona to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 02 November 2026
Visit: Spain, Morocco, Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic, Barbados
Bonus Onboard Credit
Inside
$1,294
Oceanview
$1,514
Balcony
-
Suite
$3,771
From
US$1,294
Per Person
View Trip
4 Day South Caribbean with MSC Cruises
Cruise

4 Days (3 Nights) Fort-de-France to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 March 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic
Inside
-
Oceanview
-
Balcony
$449
Suite
$719
From
US$449
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Oct 2027
Visit: Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin
Bonus Onboard Credit
Inside
$629
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$629
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Feb 2027
Visit: Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis, Barbados
Bonus Onboard Credit
Inside
$1,468
Oceanview
$1,728
Balcony
$2,608
Suite
$4,005
From
US$1,468
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Feb 2027
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis
Bonus Onboard Credit
Exclusive Savings
Inside
$1,808
Oceanview
$2,075
Balcony
$2,705
Suite
$3,831
From
US$1,808
Save 73
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Jan 2027 to Feb 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis, Barbados
Bonus Onboard Credit
Inside
$1,608
Oceanview
$1,908
Balcony
$2,861
Suite
$3,869
From
US$1,608
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2027 to Mar 2028
Visit: Dominican Republic, Aruba, Curacao, Bonaire (+5 more), Grenada, Virgin Islands, Saint Martin, Saint Kitts and Nevis, Antigua and Barbuda
Bonus Onboard Credit
Exclusive Savings
Inside
$1,168
Oceanview
$1,608
Balcony
$2,463
Suite
$3,569
From
US$1,168
Save 76
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2027 to Mar 2028
Visit: Dominican Republic, Virgin Islands, Saint Martin, Saint Kitts and Nevis (+5 more), Antigua and Barbuda, Aruba, Curacao, Bonaire, Grenada
Bonus Onboard Credit
Exclusive Savings
Inside
$1,310
Oceanview
$1,610
Balcony
$2,524
Suite
$3,629
From
US$1,310
Save 62
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Mar 2027
Visit: Dominican Republic, Virgin Islands, Saint Martin, Saint Kitts and Nevis
Bonus Onboard Credit
Inside
$729
Oceanview
$889
Balcony
$1,369
Suite
$1,907
From
US$729
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Alicante to Alicante
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Spain, Sardinia, Italy, France, Portugal
Bonus Onboard Credit
Exclusive Savings
Inside
$1,453
Oceanview
$1,573
Balcony
$2,494
Suite
$2,707
From
US$1,453
Save 52
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France, Spain
Inside
-
Oceanview
$411
Balcony
$648
Suite
-
From
US$411
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Mar 2027 to Mar 2028
Visit: Dominican Republic, Aruba, Curacao, Bonaire, Grenada
Bonus Onboard Credit
Inside
$649
Oceanview
$799
Balcony
$1,289
Suite
$1,859
From
US$649
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France, Spain, Gibraltar, Portugal, Sardinia
Inside
$1,202
Oceanview
$1,312
Balcony
$1,852
Suite
$2,736
From
US$1,202
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Mar 2027
Visit: Dominican Republic, Barbados, Martinique, Antigua and Barbuda, Virgin Islands
Bonus Onboard Credit
Inside
$689
Oceanview
$849
Balcony
$1,349
Suite
$1,887
From
US$689
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 14 January 2027
Visit: Barbados, Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin
Bonus Onboard Credit
Inside
-
Oceanview
$1,708
Balcony
$3,055
Suite
$3,772
From
US$1,708
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 01 January 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin, Barbados
Bonus Onboard Credit
Inside
$1,498
Oceanview
$1,798
Balcony
$2,676
Suite
-
From
US$1,498
Per Person
View Trip
5 Day South Africa with MSC Cruises
Cruise

5 Days (4 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ships: MSC Armonia, MSC Opera
Departures: Mar 2026 to Feb 2027
Visit: South Africa, Mozambique
Bonus Onboard Credit
Inside
$434
Oceanview
$496
Balcony
$587
Suite
$840
From
US$434
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Nov 2027
Visit: Dominican Republic, Virgin Islands, Saint Martin, Martinique, Antigua and Barbuda
Bonus Onboard Credit
Inside
$629
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$629
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 17 December 2026
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin
Bonus Onboard Credit
Exclusive Savings
Inside
$2,153
Oceanview
-
Balcony
$3,384
Suite
$4,519
From
US$2,153
Save 55
Per Person
View Trip
4 Day South Africa with MSC Cruises
Cruise

4 Days (3 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ships: MSC Armonia, MSC Opera
Departures: Mar 2026 to Mar 2027
Visit: South Africa, Mozambique
Bonus Onboard Credit
Inside
$337
Oceanview
$381
Balcony
$466
Suite
$685
From
US$337
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 November 2026
Visit: Dominican Republic, Virgin Islands, Saint Martin, Saint Kitts and Nevis
Bonus Onboard Credit
Inside
$649
Oceanview
$809
Balcony
$1,289
Suite
$1,869
From
US$649
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise

15 Days (14 Nights) Barcelona to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 02 November 2026
Visit: Spain, Morocco, Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic
Bonus Onboard Credit
Inside
$901
Oceanview
$1,075
Balcony
$1,802
Suite
$3,132
From
US$901
Per Person
View Trip
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