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MSC Opera

MSC Opera Cruises

Choose from 248 cruise vacations onboard the MSC Opera. Compare cruises ranging from 2 days to 26 days with departures available from February 2026 through to April 2028. Book with confidence supported by one of our dedicated expert CLIA cruise advisors.
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2 Days
26 Days
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$3,048pp
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56 Cruises (248 Cruise Departures)
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Italy, France, Spain, Portugal, Sardinia
Bonus Onboard Credit
Exclusive Savings
Inside
$1,222
Oceanview
$1,332
Balcony
$1,852
Suite
$2,658
From
US$1,222
Save 54
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Genoa to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 31 October 2026
Visit: Italy, France, Spain, Morocco (+4 more), Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic
Bonus Onboard Credit
Inside
$993
Oceanview
$1,185
Balcony
$2,043
Suite
$3,534
From
US$993
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 31 December 2026
Visit: Barbados, Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin
Bonus Onboard Credit
Exclusive Savings
Inside
$2,511
Oceanview
$2,812
Balcony
$3,782
Suite
$4,917
From
US$2,511
Save 67
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Lisbon to Lisbon
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Portugal, Spain, Sardinia, Italy, France
Bonus Onboard Credit
Exclusive Savings
Inside
$1,401
Oceanview
$1,521
Balcony
$2,075
Suite
$2,647
From
US$1,401
Save 54
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 11 January 2027
Visit: Dominican Republic, Barbados, Martinique, Antigua and Barbuda, Virgin Islands
Bonus Onboard Credit
Inside
$689
Oceanview
$849
Balcony
$1,349
Suite
$1,887
From
US$689
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Jan 2027 to Feb 2027
Visit: Barbados, Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis
Bonus Onboard Credit
Inside
$1,448
Oceanview
$1,768
Balcony
$3,006
Suite
$3,831
From
US$1,448
Per Person
View Trip
10 Day Mediterranean with MSC Cruises
Cruise

10 Days (9 Nights) Marseille to Genoa
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 01 October 2026
Visit: France, Spain, Portugal, Sardinia, Italy
Inside
$679
Oceanview
$839
Balcony
-
Suite
-
From
US$679
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise

16 Days (15 Nights) Marseille to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 01 November 2026
Visit: France, Spain, Morocco, Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic
Bonus Onboard Credit
Inside
$967
Oceanview
$1,150
Balcony
$1,928
Suite
$3,349
From
US$967
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 18 December 2026
Visit: Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin, Barbados
Bonus Onboard Credit
Exclusive Savings
Inside
$2,967
Oceanview
$3,258
Balcony
$4,180
Suite
$5,266
From
US$2,967
Save 81
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 20 November 2026
Visit: Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis, Barbados
Bonus Onboard Credit
Inside
-
Oceanview
$1,668
Balcony
-
Suite
-
From
US$1,668
Per Person
View Trip
5 Day South Caribbean with MSC Cruises
Cruise

5 Days (4 Nights) La Romana to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 April 2027
Visit: Dominican Republic, Barbados, Martinique
Inside
$269
Oceanview
$349
Balcony
$579
Suite
$939
From
US$269
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Nov 2027
Visit: Martinique, Antigua and Barbuda, Dominican Republic, Barbados
Bonus Onboard Credit
Inside
$629
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$629
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Genoa to Lisbon
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France, Spain, Gibraltar, Portugal
Inside
$429
Oceanview
-
Balcony
$969
Suite
$1,259
From
US$429
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Malaga to Malaga
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: Jun 2026 to Sep 2027
Visit: Spain, Portugal, Sardinia, Italy, France
Bonus Onboard Credit
Exclusive Savings
Inside
$1,531
Oceanview
$1,691
Balcony
$2,182
Suite
$2,647
From
US$1,531
Save 68
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Oct 2027
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Antigua and Barbuda
Bonus Onboard Credit
Exclusive Savings
Inside
$1,288
Oceanview
$1,578
Balcony
$2,385
Suite
$3,627
From
US$1,288
Save 50
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Marseille to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 01 November 2026
Visit: France, Spain, Morocco, Antigua and Barbuda (+5 more), Saint Martin, Saint Kitts and Nevis, Dominican Republic, Barbados, Martinique
Bonus Onboard Credit
Inside
$1,499
Oceanview
$1,649
Balcony
$3,119
Suite
$4,176
From
US$1,499
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Jan 2027
Visit: Dominican Republic, Virgin Islands, Saint Kitts and Nevis, Saint Martin
Bonus Onboard Credit
Inside
$689
Oceanview
$849
Balcony
$1,349
Suite
$1,887
From
US$689
Per Person
View Trip
4 Day South Africa with MSC Cruises
Cruise

4 Days (3 Nights) Durban to Cape Town
Cruise Line: MSC Cruises
Ships: MSC Armonia, MSC Opera
Departures: Mar 2026 to Mar 2027
Visit: South Africa
Bonus Onboard Credit
Inside
$315
Oceanview
$359
Balcony
$443
Suite
$662
From
US$315
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 15 January 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin, Barbados
Bonus Onboard Credit
Inside
$1,348
Oceanview
$1,648
Balcony
-
Suite
$3,617
From
US$1,348
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Rome to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France, Spain, Morocco (+4 more), Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic
Bonus Onboard Credit
Inside
$1,146
Oceanview
$1,630
Balcony
$2,451
Suite
$3,961
From
US$1,146
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: France, Spain, Portugal, Sardinia, Italy
Bonus Onboard Credit
Exclusive Savings
Inside
$1,486
Oceanview
$1,606
Balcony
$2,264
Suite
$2,642
From
US$1,486
Save 51
Per Person
View Trip
26 Day MSC Grand Voyages with MSC Cruises
Cruise

26 Days (25 Nights) Rome to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France, Spain, Morocco (+8 more), Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic, Barbados, Martinique, Guadeloupe, Virgin Islands
Bonus Onboard Credit
Inside
$2,094
Oceanview
$2,324
Balcony
$3,663
Suite
$5,759
From
US$2,094
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Malaga to Genoa
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 October 2026
Visit: Spain, Portugal, Sardinia, Italy
Inside
-
Oceanview
-
Balcony
$999
Suite
-
From
US$999
Per Person
View Trip
5 Day South Africa with MSC Cruises
Cruise

5 Days (4 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ships: MSC Armonia, MSC Opera
Departures: Feb 2026 to Mar 2027
Visit: South Africa, Mozambique
Bonus Onboard Credit
Inside
$430
Oceanview
$485
Balcony
$575
Suite
$828
From
US$430
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2026 to Nov 2027
Visit: Dominican Republic, Barbados, Martinique, Guadeloupe, Virgin Islands
Bonus Onboard Credit
Inside
$619
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$619
Per Person
View Trip
4 Day South Caribbean with MSC Cruises
Cruise

4 Days (3 Nights) Fort-de-France to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 November 2027
Visit: Martinique, Guadeloupe, Virgin Islands, Dominican Republic
Inside
$209
Oceanview
$279
Balcony
$449
Suite
$719
From
US$209
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 19 November 2026
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis
Bonus Onboard Credit
Inside
$1,398
Oceanview
$1,698
Balcony
-
Suite
-
From
US$1,398
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France
Inside
-
Oceanview
$311
Balcony
$460
Suite
$628
From
US$311
Per Person
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France
Inside
$79
Oceanview
$119
Balcony
-
Suite
-
From
US$79
Per Person
View Trip
5 Day South Caribbean with MSC Cruises
Cruise

5 Days (4 Nights) Bridgetown to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 11 November 2027
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic
Inside
$269
Oceanview
$349
Balcony
$579
Suite
$939
From
US$269
Per Person
View Trip
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