Home > Operators > MSC Cruises > Ships > MSC Opera > Cruises
MSC Opera

MSC Opera Cruises

Choose from 200 cruise vacations onboard the MSC Opera. Compare cruises ranging from 4 days to 26 days with departures available from June 2026 through to April 2028. Book with confidence supported by one of our dedicated expert CLIA cruise advisors.
Filter Results
Departures
Show More...
Duration
4 Days
26 Days
Regions
Start & End Cities
Price
$200pp
$3,595pp
Countries
Show More...
Filter Results
41 Cruises (200 Cruise Departures)
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: Jun 2026 to Sep 2027
Visit: Italy, France, Spain, Portugal, Sardinia
Inside
$1,079
Oceanview
$1,215
Balcony
$2,476
Suite
$2,732
From
US$1,079
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Jan 2027 to Feb 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis, Barbados
Inside
$1,784
Oceanview
$2,084
Balcony
$3,174
Suite
$4,154
From
US$1,784
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 25 February 2027
Visit: Barbados, Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis
Inside
$1,778
Oceanview
$2,088
Balcony
$3,088
Suite
$4,268
From
US$1,778
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Mar 2027 to Mar 2028
Visit: Dominican Republic, Aruba, Curacao, Bonaire, Grenada
Inside
$649
Oceanview
$799
Balcony
$1,289
Suite
$1,859
From
US$649
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Feb 2027
Visit: Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis, Barbados
Inside
$1,664
Oceanview
$1,964
Balcony
$3,418
Suite
-
From
US$1,664
Per Person
View Trip
5 Day South Caribbean with MSC Cruises
Cruise

5 Days (4 Nights) La Romana to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 April 2027
Visit: Dominican Republic, Barbados, Martinique
Inside
$269
Oceanview
$349
Balcony
$579
Suite
$939
From
US$269
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France, Spain
Inside
$500
Oceanview
-
Balcony
$789
Suite
-
From
US$500
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Lisbon to Lisbon
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: Jun 2026 to Sep 2027
Visit: Portugal, Spain, Sardinia, Italy, France
Inside
$908
Oceanview
$998
Balcony
$2,059
Suite
$2,721
From
US$908
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 November 2026
Visit: Dominican Republic, Virgin Islands, Saint Martin, Saint Kitts and Nevis
Inside
$707
Oceanview
$867
Balcony
$1,347
Suite
-
From
US$707
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Malaga to Malaga
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: Jun 2026 to Sep 2027
Visit: Spain, Portugal, Sardinia, Italy, France
Inside
$1,558
Oceanview
$1,398
Balcony
$2,210
Suite
$2,721
From
US$1,398
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 31 December 2026
Visit: Barbados, Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin
Inside
$2,578
Oceanview
$2,888
Balcony
$3,888
Suite
-
From
US$2,578
Per Person
View Trip
26 Day MSC Grand Voyages with MSC Cruises
Cruise

26 Days (25 Nights) Rome to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France, Spain, Morocco (+8 more), Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic, Barbados, Martinique, Guadeloupe, Virgin Islands
Inside
-
Oceanview
$2,806
Balcony
$3,781
Suite
$5,917
From
US$2,806
Per Person
View Trip
4 Day South Caribbean with MSC Cruises
Cruise

4 Days (3 Nights) Fort-de-France to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 November 2027
Visit: Martinique, Guadeloupe, Virgin Islands, Dominican Republic
Inside
$209
Oceanview
$279
Balcony
$449
Suite
$719
From
US$209
Per Person
View Trip
5 Day South Caribbean with MSC Cruises
Cruise

5 Days (4 Nights) Bridgetown to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 11 November 2027
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic
Inside
-
Oceanview
-
Balcony
$709
Suite
$939
From
US$709
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise

15 Days (14 Nights) Barcelona to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 02 November 2026
Visit: Spain, Morocco, Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic
Inside
$961
Oceanview
$1,068
Balcony
-
Suite
-
From
US$961
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 17 December 2026
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin
Inside
-
Oceanview
-
Balcony
$3,595
Suite
$4,765
From
US$3,595
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Oct 2027
Visit: Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin
Inside
$629
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$629
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2027 to Dec 2027
Visit: Dominican Republic, Aruba, Curacao, Bonaire (+5 more), Grenada, Virgin Islands, Saint Martin, Saint Kitts and Nevis, Antigua and Barbuda
Inside
$1,292
Oceanview
$1,592
Balcony
$2,572
Suite
$3,712
From
US$1,292
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2026 to Nov 2027
Visit: Dominican Republic, Barbados, Martinique, Guadeloupe, Virgin Islands
Inside
$629
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$629
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 18 December 2026
Visit: Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin, Barbados
Inside
$3,048
Oceanview
$3,348
Balcony
$4,298
Suite
-
From
US$3,048
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: Jun 2026 to Sep 2027
Visit: France, Spain, Portugal, Sardinia, Italy
Inside
$820
Oceanview
$1,012
Balcony
$2,468
Suite
$2,776
From
US$820
Per Person
View Trip
4 Day South Caribbean with MSC Cruises
Cruise

4 Days (3 Nights) La Romana to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 April 2027
Visit: Dominican Republic, Barbados
Inside
$209
Oceanview
$279
Balcony
$449
Suite
-
From
US$209
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Alicante to Alicante
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: Jun 2026 to Sep 2027
Visit: Spain, Sardinia, Italy, France, Portugal
Inside
$1,239
Oceanview
$1,349
Balcony
$2,403
Suite
$2,783
From
US$1,239
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 11 January 2027
Visit: Dominican Republic, Barbados, Martinique, Antigua and Barbuda, Virgin Islands
Inside
$827
Oceanview
$1,037
Balcony
$1,777
Suite
$2,147
From
US$827
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Rome to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France, Spain, Morocco (+4 more), Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic
Inside
$1,016
Oceanview
$1,458
Balcony
$2,353
Suite
$3,909
From
US$1,016
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Oct 2027
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Antigua and Barbuda
Drinks & WiFi Package
Inside
$1,448
Oceanview
$1,748
Balcony
$2,738
Suite
$3,898
From
US$1,448
Per Person
View Trip
4 Day South Caribbean with MSC Cruises
Cruise

4 Days (3 Nights) Fort-de-France to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 March 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic
Inside
-
Oceanview
$279
Balcony
$539
Suite
$719
From
US$279
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Nov 2027
Visit: Dominican Republic, Virgin Islands, Saint Martin, Martinique, Antigua and Barbuda
Inside
$629
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$629
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Mar 2027
Visit: Dominican Republic, Virgin Islands, Saint Martin, Saint Kitts and Nevis
Inside
$659
Oceanview
$869
Balcony
$1,369
Suite
$1,959
From
US$659
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Jan 2027
Visit: Dominican Republic, Virgin Islands, Saint Kitts and Nevis, Saint Martin
Inside
$767
Oceanview
$977
Balcony
$1,497
Suite
$2,087
From
US$767
Per Person
View Trip
Results: 1-30 of 41

No trips found. Try adjusting the search filters.




Cruises found! Scroll up to view.

MSC Cruises

MSC Cruises All MSC Cruises MSC Cruises Reviews

Regions

MSC African Cruises MSC Asia Cruises MSC Caribbean Cruises MSC Europe & Med Cruises MSC Greece Cruises MSC Japan Cruises MSC Northern Europe Cruises MSC South America Cruises MSC Transatlantic Cruises MSC United Arab Emirates Cruises MSC Worldwide Cruises

MSC Cruises Ships

MSC Armonia MSC Bellissima MSC Divina MSC Euribia MSC Fantasia MSC Grandiosa MSC Lirica MSC Magnifica MSC Meraviglia MSC Musica MSC Opera MSC Orchestra MSC Poesia MSC Preziosa MSC Seascape MSC Seashore MSC Seaside MSC Seaview MSC Sinfonia MSC Splendida MSC Virtuosa MSC World America MSC World Asia MSC World Europa

Cities

From Abu Dhabi From Amalfi From Athens From Barcelona From Bari From Berlin From Bridgetown From Buenos Aires From Cape Town From Copenhagen From Dubai From Durban From Florence From Fort-de-France From Funchal From Genoa From Hamburg From Istanbul From Kiel From La Romana From Las Palmas de Gran Canaria From Lisbon From London From Maceio From Malaga From Marseille From Miami From Naples From Orlando From Palermo From Paris From Pointe-A-Pitre From Rio de Janeiro From Rome From Rotterdam From Salvador From Santa Cruz de Tenerife From Santos From Sao Paulo From Shanghai From Stockholm From Tokyo From Trieste From Valencia From Venice

© 2010-2026. Global Journeys. You're viewing our site in US dollars.

    

Global Journeys | Terms & Conditions

Global Journeys Travel Inc. is a Member of the American Society of Travel Advisors (ASTA No: 900374670), CLIA (No. 00046729) & is TICO Accredited (No. 50027921).

Travel Industry Associations