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MSC Opera

MSC Opera Cruises

Choose from 210 cruise vacations onboard the MSC Opera. Compare cruises ranging from 2 days to 26 days with departures available from February 2026 through to November 2027. Book with confidence supported by one of our dedicated expert CLIA cruise advisors.
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2 Days
26 Days
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49 Cruises (210 Cruise Departures)
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Italy, France, Spain, Portugal, Sardinia
Bonus Onboard Credit
Exclusive Savings
Inside
$1,372
Oceanview
$1,482
Balcony
$2,401
Suite
$2,615
From
US$1,372
Save 53
Per Person
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France
Inside
$79
Oceanview
$119
Balcony
$199
Suite
$339
From
US$79
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise

16 Days (15 Nights) Marseille to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 01 November 2026
Visit: France, Spain, Morocco, Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic
Bonus Onboard Credit
Inside
$1,060
Oceanview
$1,260
Balcony
$2,030
Suite
$3,349
From
US$1,060
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Barcelona to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 02 November 2026
Visit: Spain, Morocco, Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic, Barbados
Bonus Onboard Credit
Inside
$1,294
Oceanview
$1,514
Balcony
-
Suite
$3,771
From
US$1,294
Per Person
View Trip
5 Day South Africa with MSC Cruises
Cruise

5 Days (4 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ships: MSC Armonia, MSC Opera
Departures: Feb 2026 to Mar 2027
Visit: South Africa, Mozambique
Bonus Onboard Credit
Inside
$419
Oceanview
$474
Balcony
$575
Suite
$817
From
US$419
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 11 January 2027
Visit: Dominican Republic, Barbados, Martinique, Antigua and Barbuda, Virgin Islands
Bonus Onboard Credit
Inside
$689
Oceanview
$849
Balcony
$1,319
Suite
$1,858
From
US$689
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Jan 2027 to Feb 2027
Visit: Barbados, Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis
Bonus Onboard Credit
Inside
$1,498
Oceanview
$1,768
Balcony
$2,638
Suite
$3,782
From
US$1,498
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 March 2027
Visit: Dominican Republic, Virgin Islands, Saint Martin, Saint Kitts and Nevis, Antigua and Barbuda
Bonus Onboard Credit
Inside
$919
Oceanview
$1,149
Balcony
$1,619
Suite
$2,149
From
US$919
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Malaga to Genoa
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 October 2026
Visit: Spain, Portugal, Sardinia, Italy
Inside
-
Oceanview
-
Balcony
$1,199
Suite
-
From
US$1,199
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Mar 2027
Visit: Dominican Republic, Barbados, Martinique, Antigua and Barbuda, Virgin Islands
Bonus Onboard Credit
Inside
$689
Oceanview
$849
Balcony
$1,319
Suite
$1,858
From
US$689
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Oct 2027
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Antigua and Barbuda
Bonus Onboard Credit
Exclusive Savings
Inside
$1,288
Oceanview
$1,578
Balcony
$2,337
Suite
$3,578
From
US$1,288
Save 50
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Malaga to Malaga
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 06 May 2026
Visit: Spain, Gibraltar, Portugal, Sardinia, Italy, France
Bonus Onboard Credit
Exclusive Savings
Inside
-
Oceanview
-
Balcony
-
Suite
$2,841
From
US$2,841
Save 80
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Genoa to Malaga
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France, Spain
Inside
-
Oceanview
-
Balcony
$509
Suite
$779
From
US$509
Per Person
View Trip
4 Day South Africa with MSC Cruises
Cruise

4 Days (3 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ships: MSC Armonia, MSC Opera
Departures: Feb 2026 to Mar 2027
Visit: South Africa, Mozambique
Bonus Onboard Credit
Inside
$337
Oceanview
$381
Balcony
$466
Suite
$685
From
US$337
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Alicante to Alicante
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Spain, Sardinia, Italy, France, Portugal
Bonus Onboard Credit
Exclusive Savings
Inside
$1,445
Oceanview
$1,525
Balcony
$2,448
Suite
$2,661
From
US$1,445
Save 50
Per Person
View Trip
4 Day South Africa with MSC Cruises
Cruise

4 Days (3 Nights) Durban to Cape Town
Cruise Line: MSC Cruises
Ships: MSC Armonia, MSC Opera
Departures: Mar 2026 to Mar 2027
Visit: South Africa
Bonus Onboard Credit
Inside
$315
Oceanview
$359
Balcony
$533
Suite
$662
From
US$315
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 17 December 2026
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin
Bonus Onboard Credit
Exclusive Savings
Inside
$2,153
Oceanview
$2,414
Balcony
$3,336
Suite
$4,471
From
US$2,153
Save 55
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Malaga to Malaga
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Spain, Portugal, Sardinia, Italy, France
Bonus Onboard Credit
Exclusive Savings
Inside
$1,451
Oceanview
$1,533
Balcony
$1,948
Suite
$2,605
From
US$1,451
Save 52
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Genoa to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 31 October 2026
Visit: Italy, France, Spain, Morocco (+4 more), Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic
Bonus Onboard Credit
Inside
$1,089
Oceanview
$1,299
Balcony
$2,099
Suite
$3,534
From
US$1,089
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 15 January 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin, Barbados
Bonus Onboard Credit
Inside
$1,348
Oceanview
$1,648
Balcony
$2,482
Suite
$3,569
From
US$1,348
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 01 January 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin, Barbados
Bonus Onboard Credit
Inside
$1,538
Oceanview
$1,798
Balcony
$2,628
Suite
$3,714
From
US$1,538
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 14 January 2027
Visit: Barbados, Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin
Bonus Onboard Credit
Inside
-
Oceanview
$1,708
Balcony
$2,579
Suite
$3,724
From
US$1,708
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Lisbon to Lisbon
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Portugal, Spain, Sardinia, Italy, France
Bonus Onboard Credit
Exclusive Savings
Inside
$1,541
Oceanview
$1,601
Balcony
$2,085
Suite
$2,605
From
US$1,541
Save 80
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: France, Spain, Portugal, Sardinia, Italy
Bonus Onboard Credit
Exclusive Savings
Inside
$1,446
Oceanview
$1,556
Balcony
$2,328
Suite
$2,600
From
US$1,446
Save 50
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Mar 2027
Visit: Dominican Republic, Virgin Islands, Saint Martin, Saint Kitts and Nevis
Bonus Onboard Credit
Inside
$709
Oceanview
$869
Balcony
$1,339
Suite
$1,877
From
US$709
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France, Spain
Inside
$359
Oceanview
$421
Balcony
$648
Suite
$872
From
US$359
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 November 2026
Visit: Dominican Republic, Virgin Islands, Saint Martin, Saint Kitts and Nevis
Bonus Onboard Credit
Inside
$629
Oceanview
$789
Balcony
$1,259
Suite
$1,839
From
US$629
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Nov 2027
Visit: Martinique, Antigua and Barbuda, Dominican Republic, Barbados
Bonus Onboard Credit
Inside
$629
Oceanview
$789
Balcony
$1,199
Suite
$1,839
From
US$629
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 18 December 2026
Visit: Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin, Barbados
Bonus Onboard Credit
Exclusive Savings
Inside
$2,967
Oceanview
$3,258
Balcony
$4,131
Suite
$5,218
From
US$2,967
Save 81
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Feb 2027
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis
Bonus Onboard Credit
Exclusive Savings
Inside
$1,808
Oceanview
$2,075
Balcony
$2,657
Suite
$3,782
From
US$1,808
Save 71
Per Person
View Trip
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