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MSC Opera

MSC Opera Cruises

Choose from 221 cruise vacations onboard the MSC Opera. Compare cruises ranging from 2 days to 26 days with departures available from March 2026 through to April 2028. Book with confidence supported by one of our dedicated expert CLIA cruise advisors.
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2 Days
26 Days
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$79pp
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52 Cruises (221 Cruise Departures)
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Italy, France, Spain, Portugal, Sardinia
Exclusive Savings
Inside
$1,163
Oceanview
$1,309
Balcony
$2,036
Suite
$2,658
From
US$1,163
Save 65
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 17 December 2026
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin
Exclusive Savings
Inside
-
Oceanview
-
Balcony
$3,498
Suite
$4,633
From
US$3,498
Save 97
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 November 2026
Visit: Dominican Republic, Virgin Islands, Saint Martin, Saint Kitts and Nevis
Inside
$707
Oceanview
$867
Balcony
$1,347
Suite
$1,954
From
US$707
Per Person
View Trip
18 Day MSC Grand Voyages with MSC Cruises
Cruise

18 Days (17 Nights) Barcelona to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 02 November 2026
Visit: Spain, Morocco, Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic, Barbados
Inside
$1,294
Oceanview
$1,514
Balcony
$2,326
Suite
-
From
US$1,294
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Feb 2027
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis
Exclusive Savings
Inside
$1,848
Oceanview
$2,075
Balcony
$2,819
Suite
$3,944
From
US$1,848
Save 76
Per Person
View Trip
5 Day South Caribbean with MSC Cruises
Cruise

5 Days (4 Nights) La Romana to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 April 2027
Visit: Dominican Republic, Barbados, Martinique
Inside
$269
Oceanview
$349
Balcony
$579
Suite
$939
From
US$269
Per Person
View Trip
2 Day Mediterranean with MSC Cruises
Cruise

2 Days (1 Nights) Genoa to Marseille
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France
Inside
$79
Oceanview
$119
Balcony
$199
Suite
$339
From
US$79
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Jan 2027 to Feb 2027
Visit: Barbados, Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis
Inside
$1,565
Oceanview
$1,885
Balcony
$2,800
Suite
$4,151
From
US$1,565
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise

16 Days (15 Nights) Marseille to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 01 November 2026
Visit: France, Spain, Morocco, Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic
Inside
$967
Oceanview
$1,150
Balcony
$1,928
Suite
$3,349
From
US$967
Per Person
View Trip
4 Day South Africa with MSC Cruises
Cruise

4 Days (3 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ships: MSC Armonia, MSC Opera
Departures: Mar 2026 to Mar 2027
Visit: South Africa, Mozambique
Inside
$370
Oceanview
$381
Balcony
$572
Suite
$704
From
US$370
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Mar 2027
Visit: Dominican Republic, Barbados, Martinique, Antigua and Barbuda, Virgin Islands
Inside
$779
Oceanview
$939
Balcony
$1,498
Suite
$1,974
From
US$779
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Oct 2027
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Antigua and Barbuda
Drinks & WiFi Package
Exclusive Savings
Inside
$1,428
Oceanview
$1,748
Balcony
$2,667
Suite
$3,792
From
US$1,428
Save 108
Per Person
View Trip
19 Day MSC Grand Voyages with MSC Cruises
Cruise

19 Days (18 Nights) Rome to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France, Spain, Morocco (+4 more), Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic
Inside
$1,146
Oceanview
$1,630
Balcony
$2,451
Suite
$3,961
From
US$1,146
Per Person
View Trip
5 Day South Africa with MSC Cruises
Cruise

5 Days (4 Nights) Durban to Durban
Cruise Line: MSC Cruises
Ships: MSC Armonia, MSC Opera
Departures: Mar 2026 to Feb 2027
Visit: South Africa, Mozambique
Inside
$434
Oceanview
$513
Balcony
$1,345
Suite
$857
From
US$434
Per Person
View Trip
4 Day South Caribbean with MSC Cruises
Cruise

4 Days (3 Nights) La Romana to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 April 2027
Visit: Dominican Republic, Barbados
Inside
$209
Oceanview
$279
Balcony
$449
Suite
$719
From
US$209
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2026 to Nov 2027
Visit: Dominican Republic, Barbados, Martinique, Guadeloupe, Virgin Islands
Inside
$559
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$559
Per Person
View Trip
6 Day South Africa with MSC Cruises
Cruise

6 Days (5 Nights) Cape Town to Cape Town
Cruise Line: MSC Cruises
Ships: MSC Armonia, MSC Opera
Departures: Apr 2026 to Mar 2027
Visit: South Africa, Namibia
Inside
$620
Oceanview
$675
Balcony
$1,099
Suite
$1,062
From
US$620
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 15 January 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin, Barbados
Inside
$1,584
Oceanview
$1,884
Balcony
-
Suite
$3,846
From
US$1,584
Per Person
View Trip
5 Day South Caribbean with MSC Cruises
Cruise

5 Days (4 Nights) Bridgetown to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 11 November 2027
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic
Inside
-
Oceanview
$399
Balcony
$579
Suite
$939
From
US$399
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Genoa to Lisbon
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France, Spain, Gibraltar, Portugal
Inside
$459
Oceanview
-
Balcony
$829
Suite
-
From
US$459
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Mar 2027
Visit: Dominican Republic, Virgin Islands, Saint Martin, Saint Kitts and Nevis
Inside
$729
Oceanview
$889
Balcony
$1,369
Suite
$1,907
From
US$729
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Nov 2027
Visit: Martinique, Antigua and Barbuda, Dominican Republic, Barbados
Exclusive Savings
Inside
$629
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$629
Save 58
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: France, Spain, Portugal, Sardinia, Italy
Exclusive Savings
Inside
$1,344
Oceanview
$1,454
Balcony
$2,155
Suite
$2,642
From
US$1,344
Save 51
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Alicante to Alicante
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Spain, Sardinia, Italy, France, Portugal
Exclusive Savings
Inside
$1,404
Oceanview
$1,462
Balcony
$2,130
Suite
$2,707
From
US$1,404
Save 52
Per Person
View Trip
10 Day Mediterranean with MSC Cruises
Cruise

10 Days (9 Nights) Marseille to Genoa
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 01 October 2026
Visit: France, Spain, Portugal, Sardinia, Italy
Inside
-
Oceanview
$899
Balcony
$1,359
Suite
-
From
US$899
Per Person
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Genoa to Malaga
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France, Spain
Inside
-
Oceanview
-
Balcony
$599
Suite
$779
From
US$599
Per Person
View Trip
4 Day South Caribbean with MSC Cruises
Cruise

4 Days (3 Nights) Fort-de-France to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 March 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic
Inside
-
Oceanview
-
Balcony
$449
Suite
$719
From
US$449
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Jan 2027 to Feb 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis, Barbados
Inside
$1,784
Oceanview
$2,032
Balcony
$2,954
Suite
$4,040
From
US$1,784
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 03 May 2026
Visit: Italy, France, Spain, Gibraltar, Portugal, Sardinia
Inside
$1,095
Oceanview
$1,134
Balcony
-
Suite
$2,736
From
US$1,095
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Mar 2027 to Mar 2028
Visit: Dominican Republic, Aruba, Curacao, Bonaire, Grenada
Inside
$649
Oceanview
$799
Balcony
$1,289
Suite
$1,859
From
US$649
Per Person
View Trip
Results: 1-30 of 52

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