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MSC Opera

MSC Opera Cruises

Choose from 210 cruise vacations onboard the MSC Opera. Compare cruises ranging from 4 days to 26 days with departures available from May 2026 through to April 2028. Book with confidence supported by one of our dedicated expert CLIA cruise advisors.
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4 Days
26 Days
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44 Cruises (210 Cruise Departures)
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Italy, France, Spain, Portugal, Sardinia
Inside
$1,253
Oceanview
$1,333
Balcony
$2,475
Suite
$2,732
From
US$1,253
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Lisbon to Lisbon
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Portugal, Spain, Sardinia, Italy, France
Inside
$971
Oceanview
$1,225
Balcony
$2,049
Suite
$2,721
From
US$971
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Jan 2027
Visit: Dominican Republic, Virgin Islands, Saint Kitts and Nevis, Saint Martin
Inside
$767
Oceanview
$977
Balcony
$1,497
Suite
$2,087
From
US$767
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Jan 2027 to Feb 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis, Barbados
Inside
$1,784
Oceanview
$2,084
Balcony
$3,034
Suite
$4,154
From
US$1,784
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Oct 2027
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Antigua and Barbuda
Inside
$1,448
Oceanview
$1,748
Balcony
$2,738
Suite
$3,898
From
US$1,448
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 25 February 2027
Visit: Barbados, Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis
Inside
$1,778
Oceanview
$2,088
Balcony
$3,088
Suite
$4,268
From
US$1,778
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 15 January 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin, Barbados
Inside
$1,584
Oceanview
$1,884
Balcony
-
Suite
-
From
US$1,584
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Malaga to Malaga
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: Jun 2026 to Sep 2027
Visit: Spain, Portugal, Sardinia, Italy, France
Inside
$1,588
Oceanview
$1,708
Balcony
$2,183
Suite
$2,721
From
US$1,588
Per Person
View Trip
26 Day MSC Grand Voyages with MSC Cruises
Cruise

26 Days (25 Nights) Rome to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France, Spain, Morocco (+8 more), Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic, Barbados, Martinique, Guadeloupe, Virgin Islands
Inside
-
Oceanview
$2,567
Balcony
$3,812
Suite
$5,948
From
US$2,567
Per Person
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Rome to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France, Spain
Inside
-
Oceanview
-
Balcony
$765
Suite
-
From
US$765
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Apr 2027 to Nov 2027
Visit: Martinique, Antigua and Barbuda, Dominican Republic, Barbados
Inside
$629
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$629
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 31 December 2026
Visit: Barbados, Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin
Inside
$2,578
Oceanview
$2,888
Balcony
$3,888
Suite
-
From
US$2,578
Per Person
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise

4 Days (3 Nights) Rome to Marseille
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 29 October 2026
Visit: Italy, France
Inside
-
Oceanview
-
Balcony
-
Suite
$628
From
US$628
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Mar 2027 to Apr 2028
Visit: Dominican Republic, Virgin Islands, Saint Martin, Saint Kitts and Nevis, Antigua and Barbuda
Inside
$579
Oceanview
$799
Balcony
$1,289
Suite
$1,859
From
US$579
Per Person
View Trip
4 Day South Caribbean with MSC Cruises
Cruise

4 Days (3 Nights) La Romana to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 April 2027
Visit: Dominican Republic, Barbados
Inside
$209
Oceanview
$279
Balcony
$449
Suite
$719
From
US$209
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 01 January 2027
Visit: Martinique, Antigua and Barbuda, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin, Barbados
Inside
$1,714
Oceanview
$1,974
Balcony
$2,924
Suite
$4,044
From
US$1,714
Per Person
View Trip
20 Day MSC Grand Voyages with MSC Cruises
Cruise

20 Days (19 Nights) Marseille to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 01 November 2026
Visit: France, Spain, Morocco, Antigua and Barbuda (+5 more), Saint Martin, Saint Kitts and Nevis, Dominican Republic, Barbados, Martinique
Inside
$1,554
Oceanview
$1,738
Balcony
-
Suite
-
From
US$1,554
Per Person
View Trip
15 Day MSC Grand Voyages with MSC Cruises
Cruise

15 Days (14 Nights) Barcelona to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 02 November 2026
Visit: Spain, Morocco, Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic
Inside
$861
Oceanview
$1,028
Balcony
-
Suite
-
From
US$861
Per Person
View Trip
5 Day South Caribbean with MSC Cruises
Cruise

5 Days (4 Nights) La Romana to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 April 2027
Visit: Dominican Republic, Barbados, Martinique
Inside
$269
Oceanview
$349
Balcony
$579
Suite
$939
From
US$269
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2027 to Dec 2027
Visit: Dominican Republic, Aruba, Curacao, Bonaire (+5 more), Grenada, Virgin Islands, Saint Martin, Saint Kitts and Nevis, Antigua and Barbuda
Inside
$1,292
Oceanview
$1,592
Balcony
$2,572
Suite
$3,712
From
US$1,292
Per Person
View Trip
17 Day MSC Grand Voyages with MSC Cruises
Cruise

17 Days (16 Nights) Genoa to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 31 October 2026
Visit: Italy, France, Spain, Morocco (+4 more), Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic
Inside
$949
Oceanview
$1,133
Balcony
-
Suite
-
From
US$949
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Bridgetown to Bridgetown
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Feb 2027
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis
Inside
-
Oceanview
-
Balcony
$2,895
Suite
$4,055
From
US$2,895
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Mar 2027
Visit: Dominican Republic, Barbados, Martinique, Antigua and Barbuda, Virgin Islands
Inside
$709
Oceanview
$919
Balcony
$1,498
Suite
$2,029
From
US$709
Per Person
View Trip
4 Day South Caribbean with MSC Cruises
Cruise

4 Days (3 Nights) Fort-de-France to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 12 November 2027
Visit: Martinique, Guadeloupe, Virgin Islands, Dominican Republic
Inside
$209
Oceanview
$279
Balcony
$449
Suite
$719
From
US$209
Per Person
View Trip
16 Day MSC Grand Voyages with MSC Cruises
Cruise

16 Days (15 Nights) Marseille to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 01 November 2026
Visit: France, Spain, Morocco, Antigua and Barbuda, Saint Martin, Saint Kitts and Nevis, Dominican Republic
Inside
$882
Oceanview
$1,049
Balcony
$1,850
Suite
$3,362
From
US$882
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Nov 2026 to Nov 2027
Visit: Dominican Republic, Barbados, Martinique, Guadeloupe, Virgin Islands
Inside
$619
Oceanview
$789
Balcony
$1,229
Suite
$1,869
From
US$619
Per Person
View Trip
8 Day South Caribbean with MSC Cruises
Cruise

8 Days (7 Nights) La Romana to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Mar 2027 to Mar 2028
Visit: Dominican Republic, Aruba, Curacao, Bonaire, Grenada
Inside
$649
Oceanview
$799
Balcony
$1,289
Suite
$1,859
From
US$649
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departures: Dec 2026 to Feb 2027
Visit: Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Martin, Saint Kitts and Nevis, Barbados
Inside
$1,704
Oceanview
$1,964
Balcony
$2,998
Suite
-
From
US$1,704
Per Person
View Trip
5 Day South Caribbean with MSC Cruises
Cruise

5 Days (4 Nights) Bridgetown to La Romana
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 11 November 2027
Visit: Barbados, Martinique, Guadeloupe, Virgin Islands, Dominican Republic
Inside
-
Oceanview
-
Balcony
$709
Suite
$939
From
US$709
Per Person
View Trip
15 Day South Caribbean with MSC Cruises
Cruise

15 Days (14 Nights) Fort-de-France to Fort-de-France
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 18 December 2026
Visit: Martinique, Guadeloupe, Virgin Islands, Dominican Republic, Saint Kitts and Nevis, Saint Martin, Barbados
Inside
$3,048
Oceanview
$3,348
Balcony
$4,298
Suite
-
From
US$3,048
Per Person
View Trip
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