Home > All River Cruises > Asia River Cruises > Mekong River Cruises > Cambodia > September 2026

Cambodia River Cruises Starting In September 2026

If you're looking at joining a river cruise through Cambodia in September 2026, we have 39 unique river cruise itineraries and 753 departures available, operated by six of the world's leading river cruise lines departing in September.
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Departures (September 2026)
< August 2026 October 2026 >
Duration
8 Days
24 Days
Countries Visited
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Price
$1,700pp
$26,465pp
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39 River Cruises (753 River Cruise Departures)
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon River Cruises
Ships: Avalon Saigon
Departures: Oct 2025 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ships: Avalon Saigon
Departures: Oct 2025 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$2,889
Save 2,172
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Uniworld River Cruises
Ships: Mekong Jewel
Departures: Dec 2025 to Dec 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,057
From
US$6,057
Save 1,462
Per Person
View Trip
24 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise
 (1)

24 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Jul 2026 to Nov 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$12,023
Suite
$12,731
From
US$12,023
Save 8,829
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
River Cruise
 (1)

16 Days Hanoi to Siem Reap
Cruise Line: Avalon River Cruises
Ships: Avalon Saigon
Departures: Oct 2025 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,530
From
US$6,530
Save 2,293
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Oct 2025 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,999
Suite
$11,999
From
US$6,999
Save 2,000
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Nov 2025 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,999
Suite
$11,999
From
US$6,999
Save 3,000
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise
 (1)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Oct 2025 to May 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$7,041
Suite
$8,962
From
US$7,041
Save 10,056
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Oct 2025 to May 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Payment Discount
Fly Free Economy
Exclusive Savings
Inside
-
River View
$5,203
Balcony
$5,688
Suite
$7,919
From
US$5,203
Save 6,456
Per Person
View Trip
19 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

19 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Aug 2026 to Sep 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
$11,160
Balcony
$12,130
Suite
$16,592
From
US$11,160
Save 325
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

10 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Aug 2026 to Dec 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
$8,537
Balcony
$9,507
Suite
$13,969
From
US$8,537
Save 289
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Northbound) with Avalon River Cruises
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Avalon River Cruises
Ships: Avalon Saigon
Departures: Oct 2025 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,099
From
US$5,099
Save 2,244
Per Person
View Trip
18 Day Highlights of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise

18 Days Hanoi to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Nov 2025 to May 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$9,530
Suite
$11,450
From
US$9,530
Save 10,073
Per Person
View Trip
18 Day Highlights of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise

18 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Oct 2025 to Apr 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$9,530
Suite
$11,450
From
US$9,530
Save 10,563
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Nov 2025 to May 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Payment Discount
Fly Free Economy
Exclusive Savings
Inside
-
River View
$3,884
Balcony
$4,369
Suite
$6,600
From
US$3,884
Save 6,415
Per Person
View Trip
13 Day Temple Discovery and Meandering along the Mekong Cruise with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Dec 2025 to Dec 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Fly Free Economy
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$6,500
Suite
$8,420
From
US$6,500
Save 8,396
Per Person
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Dec 2025 to Dec 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$7,140
Suite
$9,061
From
US$7,140
Save 8,313
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

10 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Aug 2026 to Sep 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
$8,537
Balcony
$9,507
Suite
$13,969
From
US$8,537
Save 277
Per Person
View Trip
11 Day Luxury Mekong and Temple Discovery Cruise with Scenic
River Cruise

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Oct 2025 to May 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Fly Free Premium Economy
Exclusive Savings
Inside
-
River View
-
Balcony
$6,401
Suite
$8,322
From
US$6,401
Save 10,036
Per Person
View Trip
15 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Jul 2026 to Dec 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Fly Free Economy
Exclusive Savings
Inside
-
River View
$6,199
Balcony
$6,684
Suite
$15,288
From
US$6,199
Save 5,151
Per Person
View Trip
13 Day Treasures of the Mekong with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Oct 2025 to May 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Fly Free Economy
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$7,041
Suite
$8,962
From
US$7,041
Save 9,567
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Southbound) with Avalon River Cruises
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ships: Avalon Saigon
Departures: Nov 2025 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,032
From
US$4,666
Save 2,242
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

21 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Exclusive Savings
Inside
-
River View
$7,510
Balcony
$7,995
Suite
$10,226
From
US$7,510
Save 5,635
Per Person
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Siem Reap to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Dec 2025 to Dec 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Fly Free Economy
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$7,140
Suite
$9,061
From
US$7,140
Save 8,416
Per Person
View Trip
13 Day Meandering along the Mekong and Temple Discovery Cruise with Scenic
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Dec 2025 to Dec 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$6,500
Suite
$8,420
From
US$6,500
Save 8,293
Per Person
View Trip
15 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Aug 2026 to Dec 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Exclusive Savings
Inside
-
River View
$9,856
Balcony
$6,684
Suite
$15,288
From
US$6,684
Save 5,666
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Oct 2025 to May 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Payment Discount
Exclusive Savings
Inside
-
River View
$6,508
Balcony
$6,993
Suite
$9,224
From
US$6,896
Save 6,486
Per Person
View Trip
22 Day Essence of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise

22 Days Hanoi to Ho Chi Minh City
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Oct 2025 to Apr 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Fly Free Economy
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$10,712
Suite
$12,632
From
US$10,712
Save 11,714
Per Person
View Trip
22 Day Essence of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise

22 Days Hanoi to Siem Reap
Cruise Line: Scenic
Ship: Scenic Spirit
Departures: Sep 2026 to May 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Booking Savings
Exclusive Savings
Inside
-
River View
-
Balcony
$10,712
Suite
$12,632
From
US$10,712
Save 7,593
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Uniworld River Cruises
Ships: Mekong Jewel
Departures: Nov 2025 to Dec 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,313
From
US$5,313
Save 1,186
Per Person
View Trip
Results: 1-30 of 39

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Trip Lengths

10 Day

Departure Months

October 2025 November 2025 December 2025 January 2026 February 2026 March 2026 April 2026 May 2026 July 2026 August 2026 September 2026 October 2026 November 2026 December 2026 January 2027 February 2027 March 2027 April 2027 May 2027 July 2027 August 2027 September 2027 October 2027 November 2027 December 2027

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City

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