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MSC Sinfonia

MSC Sinfonia Cruises

Choose from 240 cruise vacations onboard the MSC Sinfonia. Compare cruises ranging from 5 days to 32 days with departures available from April 2026 through to March 2028. Book with confidence supported by one of our dedicated expert CLIA cruise advisors.
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32 Days
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50 Cruises (240 Cruise Departures)
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Italy, France, Spain, Portugal, Sardinia
Inside
$1,302
Oceanview
$1,412
Balcony
$2,288
Suite
$2,732
From
US$1,302
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Mar 2028
Visit: Italy, Spain, France
Inside
$580
Oceanview
$716
Balcony
$1,036
Suite
$1,316
From
US$580
Per Person
View Trip
29 Day MSC Grand Voyages with MSC Cruises
Cruise

29 Days (28 Nights) Genoa to Durban
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 15 October 2027
Visit: Italy, France, Sardinia, Sicily (+7 more), Greece, Cyprus, Egypt, Seychelles, Mauritius, Reunion, South Africa
Inside
$2,359
Oceanview
$3,149
Balcony
$4,739
Suite
$5,869
From
US$2,359
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Alicante to Alicante
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Spain, Sardinia, Italy, France, Portugal
Inside
$1,409
Oceanview
$1,529
Balcony
$2,492
Suite
$2,783
From
US$1,409
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Athens to Bari
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 16 June 2026
Visit: Greece, Italy
Inside
$407
Oceanview
-
Balcony
$807
Suite
$967
From
US$407
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Alicante to Alicante
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departures: Jun 2027 to Sep 2027
Visit: Spain, Sardinia, Italy, France, Portugal
Inside
$1,643
Oceanview
$1,843
Balcony
$2,513
Suite
$2,733
From
US$1,643
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: France, Spain, Portugal, Sardinia, Italy
Inside
$1,228
Oceanview
$1,338
Balcony
$2,496
Suite
$2,716
From
US$1,228
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departures: Apr 2027 to May 2027
Visit: Italy, France, Spain, Morocco, Portugal
Inside
$1,642
Oceanview
$1,842
Balcony
$2,512
Suite
$2,732
From
US$1,642
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departures: Apr 2027 to May 2027
Visit: Italy, France, Spain, Morocco, Portugal
Inside
$1,562
Oceanview
$1,762
Balcony
$2,432
Suite
$2,652
From
US$1,562
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 12 April 2027
Visit: France, Italy, Spain
Inside
$850
Oceanview
$1,020
Balcony
-
Suite
$1,540
From
US$850
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Mar 2028
Visit: Italy, Spain, France
Inside
$596
Oceanview
$773
Balcony
$1,053
Suite
$1,333
From
US$596
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Bari to Valencia
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 24 October 2026
Visit: Italy, Greece, Sicily, Spain
Inside
$935
Oceanview
$1,145
Balcony
$1,565
Suite
$1,795
From
US$935
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Bari to Bari
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: Apr 2026 to Oct 2027
Visit: Italy, Greece
Inside
$519
Oceanview
$709
Balcony
$1,029
Suite
$1,372
From
US$519
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departures: Apr 2027 to May 2027
Visit: France, Spain, Morocco, Portugal, Italy
Inside
$1,546
Oceanview
$1,746
Balcony
$2,416
Suite
$2,636
From
US$1,546
Per Person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise
 (2)

7 Days (6 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: Oct 2026 to Oct 2027
Visit: Greece, Italy
Inside
$782
Oceanview
$981
Balcony
$1,177
Suite
$1,599
From
US$782
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Valencia to Valencia
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Sinfonia
Departures: Nov 2026 to Mar 2028
Visit: Spain, France, Italy
Inside
$565
Oceanview
$679
Balcony
$999
Suite
$1,279
From
US$565
Per Person
View Trip
5 Day Mediterranean with MSC Cruises
Cruise

5 Days (4 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 14 October 2027
Visit: Italy, France, Sardinia
Inside
$632
Oceanview
$712
Balcony
$980
Suite
$1,068
From
US$632
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Sinfonia
Departures: Nov 2026 to Mar 2028
Visit: Spain, France, Italy
Inside
$616
Oceanview
$751
Balcony
$1,088
Suite
$1,328
From
US$616
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 07 May 2027
Visit: Italy, France, Spain, Morocco, Gibraltar
Inside
$1,642
Oceanview
$1,842
Balcony
$2,512
Suite
$2,732
From
US$1,642
Per Person
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Athens to Valencia
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 26 October 2026
Visit: Greece, Sicily, Spain
Inside
$419
Oceanview
$569
Balcony
$909
Suite
$1,109
From
US$419
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Lisbon to Lisbon
Cruise Line: MSC Cruises
Ships: MSC Opera, MSC Sinfonia
Departures: May 2026 to Sep 2027
Visit: Portugal, Spain, Sardinia, Italy, France
Inside
$1,204
Oceanview
$1,342
Balcony
$2,201
Suite
$2,721
From
US$1,204
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Lirica, MSC Sinfonia
Departures: Nov 2026 to Mar 2028
Visit: France, Italy, Spain
Inside
$562
Oceanview
$762
Balcony
$1,042
Suite
$1,322
From
US$562
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (2)

8 Days (7 Nights) Athens to Athens
Cruise Line: MSC Cruises
Ships: MSC Orchestra, MSC Sinfonia
Departures: May 2026 to Oct 2027
Visit: Greece, Italy
Inside
$616
Oceanview
$856
Balcony
$1,126
Suite
$1,396
From
US$616
Per Person
View Trip
7 Day Mediterranean with MSC Cruises
Cruise

7 Days (6 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 08 April 2027
Visit: Italy, Spain, France
Inside
$731
Oceanview
$851
Balcony
$1,131
Suite
$1,331
From
US$731
Per Person
View Trip
14 Day Mediterranean with MSC Cruises
Cruise

14 Days (13 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 14 April 2027
Visit: Italy, Spain, France, Morocco, Portugal
Inside
$1,608
Oceanview
$1,867
Balcony
-
Suite
$2,866
From
US$1,608
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Malaga to Malaga
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 11 May 2027
Visit: Spain, Morocco, Gibraltar, Italy, France
Inside
$1,651
Oceanview
$1,851
Balcony
$2,521
Suite
$2,741
From
US$1,651
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departures: Nov 2026 to Nov 2026
Visit: France, Italy, Spain
Inside
$751
Oceanview
$991
Balcony
$1,281
Suite
$1,511
From
US$751
Per Person
View Trip
26 Day MSC Grand Voyages with MSC Cruises
Cruise

26 Days (25 Nights) Rome to Durban
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 18 October 2027
Visit: Italy, Sicily, Greece, Cyprus (+5 more), Egypt, Seychelles, Mauritius, Reunion, South Africa
Inside
$2,079
Oceanview
$2,799
Balcony
$4,229
Suite
$5,229
From
US$2,079
Per Person
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departure: 15 November 2026
Visit: Spain, France, Italy
Inside
$791
Oceanview
$991
Balcony
$1,310
Suite
$1,540
From
US$791
Per Person
View Trip
11 Day Mediterranean with MSC Cruises
Cruise

11 Days (10 Nights) Lisbon to Lisbon
Cruise Line: MSC Cruises
Ship: MSC Sinfonia
Departures: Jun 2027 to Sep 2027
Visit: Portugal, Spain, Sardinia, Italy, France
Inside
$1,691
Oceanview
$1,891
Balcony
$2,561
Suite
$2,781
From
US$1,691
Per Person
View Trip
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