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Mekong Serenity

Mekong Serenity Cruises

Choose from 277 cruise holidays onboard the Mekong Serenity. Compare cruises ranging from 11 days to 100 days with departures available from August 2026 through to April 2028. Book with confidence supported by one of our dedicated expert CLIA cruise advisors.
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10 Cruises (277 Departures)
10 Cruises (277 Departures)
Departures
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Duration
11 Days
100 Days
Start & End Cities
Price
$3,900pp
$100,000pp
Countries
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13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (9)

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$4,913
Suite
$6,868
From (Per Person)
A$4,913
Save 4,282
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (6)

21 Days Hanoi to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$10,993
Suite
$12,948
From (Per Person)
A$10,993
Save 3,806
Per Person
View Trip
25 Day Vietnam and Cambodia Grand Tour with APT
Tour + River Cruise
 (5)

25 Days Hanoi to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$13,053
Suite
$15,008
From (Per Person)
A$13,053
Save 3,842
Per Person
View Trip
13 Day Vietnam and Cambodia Highlights with APT
Tour + River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$5,697
Suite
$7,652
From (Per Person)
A$5,697
Save 3,804
Per Person
View Trip
21 Day Best of Vietnam and Cambodia with APT
Tour + River Cruise
 (3)

21 Days Ho Chi Minh City to Ho Chi Minh City
Cruise Line: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$11,679
Suite
$13,634
From (Per Person)
A$11,679
Save 3,824
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (3)

17 Days Hanoi to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$8,443
Suite
$10,398
From (Per Person)
A$8,443
Save 4,052
Per Person
View Trip
17 Day Vietnam and Cambodia Discovery with APT
Tour + River Cruise
 (2)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: APT
Ships: Mekong Serenity
Departures: Sep 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$8,835
Suite
$10,790
From (Per Person)
A$8,835
Save 4,060
Per Person
View Trip
11 Day Spiritual Cambodia and the Mekong with APT
Tour + River Cruise

11 Days Ho Chi Minh City to Siem Reap
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$3,932
Suite
$5,887
From (Per Person)
A$3,932
Save 3,563
Per Person
View Trip
100 Day APT 100 Day World Tour with APT
New ReleaseTour

100 Days Melbourne to Melbourne
Operator: APT
Ship: Mekong Serenity
Departure: 19 July 2027
Trip Styles: Coach, River Cruise, 4WD, Wildlife, Cultural, Scenic, Rocky Mountaineer
Visits: Australia, Czech Republic, Slovakia, Hungary +9 more, Austria, Germany, Holland, Spain, Portugal, Canada, Vietnam, Cambodia, New Zealand
Exclusive Savings
From (Per Person)
A$98,070
Save 1,930
Per Person
View Trip
11 Day Spiritual Cambodia and The Mekong with APT
Tour + River Cruise

11 Days Siem Reap to Ho Chi Minh City
Cruise Line: APT
Ships: Mekong Serenity
Departures: Aug 2026 to Apr 2028
Rivers: Mekong
Visits: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$4,618
Suite
$6,573
From (Per Person)
A$4,618
Save 3,081
Per Person
View Trip
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