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Miami to LA via Panama Canal

5.0/5 Based on 1 Reviews No Booking FeesDedicated Cruise Advisor
Our Price From
US$2,850
Port charges, taxes and fees included
 Cruise Length
17 Days
 Cruise Starts
Miami
 Cruise Finishes
Los Angeles
17 Day Miami to LA via Panama Canal Itinerary (Virgin Voyages)
Countries Explored: USA, Colombia, Panama, Costa Rica, Guatemala, Mexico
Ship
Departures
Passengers
2770
Crew
1,150
Launched
2025
Cruise Code
16NMLAX

Overview

This 16-night one-way truly is a once-in-a-lifetime odyssey. From Miami, you’ll sail to Cartagena, followed by Colon, Panama. Marvel at the view (while being part of it) across the Panama Canal then onward to Guatemala’s volcanic coast. Next, you’ll sail to Cabo San Lucas (known for its endless activities) before arriving on the famed shores of Los Angeles.

Cruise Itinerary

Departs: 5:00PM

From the art scene in Wynwood to the shores of Miami Beach, Florida's Magic City is a perfect collision of relaxation and tradition.

This multicultural city where the sun rules supreme is more than just a cruise port. Whether you're getting down at a taco shop-turned live music performance, immersing yourself in Cuban tradition in Little Havana or lounging on a yacht, Miami makes for one perfect destination.

PortMiami is Virgin Voyages home port and ships will dock at their private terminal overlooking the Miami skyline.

Relax and rejuvenate. Take a deep breath, and give yourself the gift of a little pampering. Relaxing onboard is already easy – but we’re making it even easier. Whether you’re in desperate need of a break from the kids, looking for intimate couples time, or just need some solo r&r, wellness is a cornerstone of our philosophy, and our cruise experience. Get a couples massage in our Redemption Spa, take a free sunrise yoga class, or jog around our outdoor track with stunning panoramic ocean views.

Arrives: 9:00AM Departs: 5:00PM

Cartagena is a feast for the senses, with its consistently warm air, bright colours, history and nightlife. Filled with legends, romance and splendour, the walled city features Spanish colonial architecture, cobblestone streets, and cultural sites. Ships will dock at this port.

Top Things to Do in Cartagena:

  • join a walking tour through the city
  • visit the Rosario Islands
  • explore the Castillo San Felipe de Barajas
  • visit the chocolate or emerald museums
  • wander the streets of Old Town and the Plaza Santo Domingo

Arrives: 11:00AM Departs: 8:00PM

Home to the Panama Canal's Atlantic Ocean entryway, Colón was founded as a result of the California gold rush in 1850, the starting point of a railroad that carried prospectors across the Isthmus of Panama. Ships will dock at the cruise terminal.

Top Things to Do in Colon:

  • explore Portobelo National Park
  • watch ships pass through the Panama Canal
  • check out the old quarter of Panama city, Casco Viejo
  • shop until you drop at the Duty-Free Zone
  • ride a vintage train on the Panama Railway

The Panama Canal, a marvel of engineering, links the Atlantic and Pacific Oceans, facilitating global maritime trade. Stretching approximately 80km/50mi, this intricate waterway features three locks - Miraflores, Pedro Miguel, and Gatun - that elevate and lower vessels to overcome the variation in sea levels.

The Miraflores Locks' visitor center offers an insightful experience, allowing observers to witness massive ships navigating the locks. The Gatun Locks, a crucial part of the canal, showcase the impressive process of raising and lowering water levels to enable the passage of ships.

Traversing the Panama Canal provides a firsthand glimpse into the intricate operations that have shaped international shipping for over a century.

For the 'do-nothings,' the 'do-somethings' and the 'do-literally-everythings' (you know who you are), we have tons of group fitness classes on board so that you can sea the world and keep your #FitnessGoals going.

From sunrise yoga and outdoor boxing to a cycling studio and bungee workouts - you’ll have full access to classes and state-of-the-art gym equipment for unlimited opportunities to break a sweat. And if you’re not the working out kind, well, the views are nice from the gym?

Arrives: 9:00AM Departs: 6:00PM

Puntarenas beckons with its rich tapestry of lush landscapes making it a vibrant spot for adventure and relaxation. This coastal city is a treasure trove of biodiversity, offering thrilling activities like zip-lining and river rafting amidst its natural parks, and is a haven for wildlife enthusiasts eager to spot sloths, scarlet macaws, and capuchin monkeys in their natural habitats.

The city's history is as rich as its landscapes, from its indigenous roots to its emergence as a vital coffee exporting hub. Today, Puntarenas thrives with cultural landmarks such as the Casa de la Cultura and the Marine History Museum, blending educational experiences with natural exploration. Whether it's wandering through the Paseo de los Turistas, visiting the NATUWA Macaw Sanctuary, or exploring the Monteverde Cloud Forest, Puntarenas offers a unique blend of cultural and ecological wonders for every traveller.

Port:Puerto Caldera

Puerto Caldera's cruise terminal is approximately 23 kilometers (about 14 miles) from the city of Puntarenas, around 30 minutes away. For transportation, you can opt for taxis, which are readily available at the port, or consider an organized shore excursion to maximize your visit. A must-see is the Monteverde Cloud Forest Reserve, offering a glimpse into the country's diverse flora and fauna.

With a festival-like lineup featuring original, first-to-sea productions, extraordinary pop-up acts, and immersive experiences, the entertainment you’ll experience on board is something you’ve never seen before. It’s wild. It’s thought-provoking. It’s a full-on extravaganza. And it couldn’t be anything else. Digging deep into our musical roots, we’ve collaborated with the world’s most-talked-about directors, choreographers, and artists to create the live entertainment only a Virgin brand could.

Arrives: 8:00AM Departs: 8:00PM

Puerto Quetzal, Guatemala’s principal Pacific Ocean port, is a gateway to some of the country’s most captivating attractions. While primarily a launch point for nearby destinations, its proximity to key sites allows visitors to delve into the rich tapestry of local culture and history swiftly. From here, the colonial beauty of Antigua, a UNESCO World Heritage site with its well-preserved Spanish Baroque architecture and stunning volcano views, is easily accessible (approx. 1hr15m drive - 90 km/56mi away).

For those interested in the natural beauty of Guatemala, the surrounding area offers activities such as visits to coffee plantations in the highlands where the unique, aromatic beans are cultivated. Additionally, the coastal town of Monterrico is within reach, known for its black volcanic sand beaches and as a nesting ground for sea turtles, making Puerto Quetzal a strategic starting point for exploring Guatemala’s diverse landscapes.

On our voyages, the biggest choice you’ll have to make is: which activity do I choose tonight? From our adult-oriented performances in the Red Room to live music every single night, bookable karaoke rooms, and special activations popping up all around the ship like pub crawls and pajama parties, there’s no shortage of things to do on a cruise with Virgin Voyages.

Arrives: 8:00AM Departs: 5:00PM

Cabo San Lucas is the sunny resort town on the tip of Mexico’s Baja California. This colourful small town is known for its excellent big-game fishing, great diving spots and challenging surf waves. Ships will anchor offshore in Cabo San Lucas bay and tender guests to shore.

Top things to do in Cabo San Lucas:

  • catch the sunset at El Arco de Cabo San Lucas
  • snorkel the coral reefs along the Sea of Cortez
  • relax on Medano beach
  • explore nearby Todos Santos

On our voyages, the biggest choice you’ll have to make is: which activity do I choose tonight? From our adult-oriented performances in the Red Room to live music every single night, bookable karaoke rooms, and special activations popping up all around the ship like pub crawls and pajama parties, there’s no shortage of things to do on a cruise with Virgin Voyages.

Arrives: 6:30AM

Los Angeles, a sprawling Southern California city, is famed not only for its influence on the entertainment industry but also for its diverse cultural offerings and sunny coastline. Highlights include the Getty Center, where art and stunning architecture meet in an expansive hilltop setting, and the historic Griffith Observatory, which offers panoramic views of the city and beyond.

For those disembarking mid-morning, a stroll through the vibrant streets of Santa Monica or a visit to the eclectic Venice Beach Boardwalk provides a perfect slice of local life. Both are excellent spots to enjoy the quintessential SoCal sun, sand, and surf, complete with shops, street performers, and seaside eateries.

Note: Ship ports may not be located in the starting & ending cities listed. Port and transfer details will be provided in your travel documentation. The provided itinerary is for informational purposes only. Activities and sightseeing attractions listed may not be available or achievable within the time in port.

Life Onboard Brilliant Lady

Brilliant Lady
Brilliant Lady

Designed for adult only guests, Sailors will enjoy cool interiors and outdoor spaces, chic bars and city styled eateries. Read more

A Dose of Vitamin Sea
A Dose of Vitamin Sea

Wellbeing is at the forefront of the onboard experience with a mix of high energy fun balanced with relaxation and rejuvenation. Read more

Festival Style Entertainment
Festival Style Entertainment

Original performances, cutting edge, boundary pushing productions and pop up performances make for lively onboard entertainment. Read more

20+ Eateries, All Included
20+ Eateries, All Included

Throw away cruise dining traditions, Brilliant Lady offers more than 20 city styled eateries, all inclusive in your fare. Read more

We’re Shakin' It Up!
We’re Shakin' It Up!

We’ve partnered with some of the industry's most esteemed mixologists to offer quality drinks without the premium price tag. Read more

Always Included Luxury
Always Included Luxury

We've taken care of all the details — so all you have to do is kick back and have the relaxing vacation you deserve. Read more

Brilliant Lady Reviews (1) Most Recent 'Brilliant Lady' Reviews

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Average Rating 5.0 / 5
1 Review
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Great service 0 , ID, United States, Sep 2025
Brielle made everything go smoothly. She's quick to answer questions and takes the stress out of planning. Very happy with her service.

Dates & Pricing USD USD

Cabin Layout Options:

Select Cabin Preference:

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Saturday 21 Mar 2026 21 Mar 26 Miami
Monday 06 Apr 2026 06 Apr 26 Los Angeles
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Brilliant Lady
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US$3,452
Twin Share (Per Personpp)
Friday 26 Mar 2027 26 Mar 27 Miami
Sunday 11 Apr 2027 11 Apr 27 Los Angeles
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Brilliant Lady
Inside
US$2,850
Twin Share (Per Personpp)
Note
Tour & cruises prices are per person. Prices shown have savings applied, are subject to availability and may be withdrawn at any time without notice. Pricing and trip details are correct at this point in time, however are subject to confirmation at the time of booking and are subject to change by Virgin Voyages. For cruise itineraries, cabin images are sourced from the cruise-line and should be treated as indicative only. Cabin inclusions, upholsteries and room layout may differ to the image(s) shown depending on the ship selected and your sailing dates.

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