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Best of South America with Amazon Cruise

23 Days Santiago to Iquitos
Best of South America with Amazon Cruise
Best of South America with Amazon Cruise
Best of South America with Amazon Cruise

Overview

Book online and enjoy exclusive savings on APT's 23 Day Best of South America with Amazon Cruise. Dive into the heart of Chile, Argentina, Brazil and Peru. Explore the Peruvian Amazon rainforest and be awestruck by Iguazu Falls, the Sacred Valley and Machu Picchu. Plus, enjoy stays in Santiago, Buenos Aires, Rio de Janeiro, Cusco and Lima.
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There are currently no departures available on this trip. Either the season has ended and new dates will be released soon, or the itinerary has been updated and isn’t operating this season.
Trip Length
Cruise Length

23 Days

Trip Starts
Cruise Starts

Santiago

Trip Ends
Cruise Ends

Iquitos

Countries Visited
Countries Visited:
Countries Visited
Rivers Sailed:
Cruise Line
Cruise Line
APT
Cruise Ship
Cruise Ship
Delfin III
Passengers
Passengers

44

Crew
Crew

29

Ship Launch
Launched

2015

Ship Refurbished
Refurbished

2021

Cruise Code
Cruise Code

ISD23

Itinerary

Welcome to Santiago. We'll meet you on arrival and transfer you to your hotel.

Tonight, join a welcome dinner. Stay Three Nights: The Singular Santiago (D)

Travel to the coastal city of Valparaiso, where you'll find colourful cliffside houses sloping down to the sea. Known to Chileans as the ‘Jewel of the Pacific', the city is an eclectic, sometimes chaotic mix of art, culture and commerce. Enjoy a Signature Experience before relaxing over lunch at a local vineyard and then returning to Santiago. (B/L)

Signature Experiences:
  • Explore this World Heritage-listed city's historic quarter before a funicular ride offering great views over Valparaiso.

This morning you'll set off on a guided discovery of the vibrant Chilean capital, which is wedged between the snow-capped Andes Mountains and the Pacific Ocean. Enjoy an afternoon at your leisure before choosing where to dine this evening. (B/D)

Freedom of Choice:
  • Perhaps savour traditional Chilean cuisine at the charming Bar Liguria or indulge in dinner at the modern Ambrosia Restaurant.

Fly to Buenos Aires, Argentina's elegant capital. On arrival, we'll transfer you to your hotel in the city's prominent Recoleta district. Home to some of Argentina's wealthiest families, Recoleta is a leafy neighbourhood dotted with beautiful parks and grand mansions just north of the city centre. Stay Three Nights: Buenos Aires, Alvear Palace Hotel (B)

Signature Experiences:
  • In Buenos Aires, enjoy a taste of local culture with a tango demonstration and a selection of tapas.

Join a guided discovery of the city, which includes the Italian-influenced barrio of La Boca, a neighbourhood known for its Latino vibe and brightly painted pedestrian streets. Explore the bohemian district of Palermo, filled with trendy eateries and galleries, before arriving at La Recoleta Cemetery. This is the resting place of Argentine notables such as the nation's former First Lady Eva Peron. (B/D)

Freedom of Choice:
  • Tonight, choose from three dining options: dinner and a tango show; dine in style at Alvear Grill; or sit down to a traditional Argentinian Asado experience.

Design your day one of three ways with Freedom of Choice Touring. (B)

Freedom of Choice:
  • Perhaps journey to the island of Tigre for a cruise along the waterways of the Parana Delta. Discover daily life within this maze of rainforest and tiny islands, which is also a haven for birdlife. Or you might like to explore the Parisian influence on Buenos Aires during a walking tour. Alternatively, join a fascinating tour of the iconic and majestic Teatro Colon, considered the world's leading opera house by acoustic finesse, and immerse yourself in the city's sophisticated high arts scene.

This morning, fly to Iguazu Falls. This natural wonder straddles the Argentina-Brazil border. Arriving on the Argentinian side, set off on the Rainforest Ecological Train to a series of walkways and viewing points, including one to the 80-metre-deep Devil's Throat. Stay Two Nights: Iguaza Falls, Belmond Hotel das Cataratas (B/D)

Signature Experiences:
  • Stay within Brazil's Iguacu National Park for two nights, enjoying the property's unrivalled location.

Spanning a width of some 2.7 kilometres, Iguazu Falls is made up of roughly 275 waterfalls waiting to be explored today. Soak up panoramic views of the falls with a leisurely walk between each of the viewing platforms. Later, see the falls from an entirely different perspective on a Freedom of Choice activity. (B)

Freedom of Choice:
  • Get up close to the roaring cascades of Iguazu Falls on an included jet boat safari, or for a special bird's-eye-view, soar over the falls on a helicopter flight.
Signature Experiences:
  • Indulge in a cachaca tasting this evening at your hotel, which boasts one of the largest cachaca collections in Brazil. In celebration of Brazil's national spirit, well known as the key ingredient in the Caipirinha cocktail, a cachaca sommelier will lead you on a delightful journey of flavours.

Begin your day with a visit to Parque das Aves bird sanctuary where you'll see a spectacular array of colourful native South American birds.

Later, fly to Rio de Janeiro, Brazil's most visited and naturally blessed city, set between lush forest mountains and sandy shores.

On arrival, we'll meet and transfer you to the elegant art deco grandeur of your hotel opposite the golden sands of iconic Copacabana Beach. Stay Three Nights: Rio De Janeiro, Belmond Copacabana Palace (B)

See Rio de Janeiro from above with a visit to Corcovado, the mountain famed for its Christ the Redeemer statue, the world's largest art deco sculpture. From here, enjoy sweeping city views. Towards evening, board a cable car to the summit of Sugarloaf Mountain to toast the sunset and incredible views with a drink.

Tonight, dine at a local restaurant on Brazil's famously delicious barbecue fare. (B/D)

Today, join a Freedom of Choice activity to experience more of Rio de Janeiro. (B)

Freedom of Choice:
  • This morning is set aside for you to sail the waters of Guanabara Bay aboard a schooner sailing ship. If you'd prefer to stay on dry land, perhaps join a colonial walking tour, where the legends woven through the city's narrow colonial-era streets are brought to life.

After breakfast this morning, be transferred to the airport for your included flight to Lima, where we'll meet you and transfer you to your hotel. Savour a delicious lunch at Cafe del Museo before enjoying a visit to Larco Museum. Stay Two Nights: Country Club Lima Hotel (B/L)

Discover the Peruvian capital's World Heritage-listed historic centre with an expert guide today. Afterwards, enjoy a Signature Experience at a private hacienda before visiting the ruins of Pachacamac. (B/L)

Signature Experiences:
  • Pay a visit to a private hacienda to enjoy lunch and a Peruvian Paso horse show.

After breakfast today, we'll transfer you to the airport for your included flight to Cusco, the pre-Columbian Inca capital of Peru. From here, be transferred to your hotel before a visit to the working corn farm Hacienda Sarapampa, where you'll enjoy a delicious farm-to-table lunch. Stay Two Nights: Sacred Valley, Tambo del Inka, A Luxury Collection Resort & Spa (B/L)

Travel to Chinchero, a small village in the Sacred Valley tucked into the Andean highlands. Enjoy a special welcome from the local Misminay community followed by a Signature Experience which demonstrates a craft passed down through generations. Continue exploring the Sacred Valley with a guide, including another Signature Experience exploring the stunning landscapes of the Salineras de Maras. Enjoy dinner at your hotel this evening. (B/D)

Signature Experiences:
  • Enjoy a traditional weaving demonstration which reveals how South America's colourful materials are created by hand.
  • See the glistening salt pools spill over the terraced slopes at the World Heritage-listed Salt Mines of Maras. Visit the circular Moray Inca terraces archaeological site.

Today is set aside for a remarkable journey to Machu Picchu as you board Inca Rail's First Class Train for your Signature Experience. Stay: Machu Picchu, Sumaq Hotel (B/L/D)

Signature Experiences:
  • Board Inca Rail's First Class Train and travel through forested landscapes to the lost Inca citadel of Machu Picchu. Enjoy a gourmet Andean-inspired lunch on board while taking in the view.

This morning, you'll enjoy a full immersion into the natural setting and incredible heritage of Machu Picchu as you set off on a locally guided exploration of the lost city of the Incas, one of the New Seven Wonders of the World.

Later, board the 360° Machu Picchu Train for your return trip to the Sacred Valley. Here, transfer by coach to Cusco and settle into your hotel in the heart of this historic city. Stay Two Nights: Cusco, Palacio del Inka, a Luxury Collection Hotel (B/L)

A guided discovery of Cusco takes you to Plaza de Armas, a square at the city's historic heart. You'll also visit the sacred site of Koricancha and the historic citadel Sacsayhuaman. This afternoon, delve into Peruvian culture on a Freedom of Choice experience. This evening, dine on flavours of Peru at MAP Cafe, located in the central courtyard of the Museum of Pre-Columbian Art. (B/D)

Freedom of Choice:
  • Indulge in marvellous five-star Peruvian cuisine as you learn the ropes from the experts with a lunchtime cooking class at Rooftop Kitchen Cusco overlooking the city. Alternatively, set out for a visit to the beautiful Cusco Cathedral.

Board an early flight via Lima to Iquitos, a city located on the banks of the Peruvian Amazon. Here, you'll step aboard your boutique vessel and set off to discover the spectacular flora and fauna as you explore the Pacaya-Samiria National Reserve. Naturalist guides will reveal the secrets of the rainforest and its inhabitants; taking skiff boats to hidden corners of the river, trail walks through the lush vegetation, or on a gentle kayak in calm creeks.

This afternoon, embark on a skiff exploration along the Maranon River and listen to the rhythmic sounds of the jungle as you settle in. Stay Four Nights: Delfin III (B/D)

Spend the morning on the waters of the Samiria River on a skiff exploration. Travel on a stable and safe boat accompanied by an expert naturalist guide and learn about this part of the river. After lunch, relax back on board before the afternoon's excursions. During the low water season (June – October), ascend to the rainforest canopy on a suspended walkway, one of the longest treetop walks in the world, and enjoy a bird's-eye view of the Amazon and its elevated ecosystem. In the high water season (November – May), embark on another fascinating skiff excursion or try your luck at piranha fishing. (B/L/D)

Get even closer to the water on a kayaking trip in the calm waters of the Reserve at Yanayacu-Pucate. Then, search for more amazing creatures and vegetation, as your naturalist guide takes you deep into the rainforest on a jungle walk at Fundo Casual. Get an intimate view of the Amazon's ecosystem and wildlife inhabiting this unique environment including frogs, snakes and insects. (B/L/D)

Today you have the chance to fish for piranhas on the Yarapa River and discover other exotic animals who call the river home. As you cruise, watch for scarlet macaws, Amazonian parrotlets, iguanas and squirrel monkeys. (B/L/D)

Your cruise ends with a transfer to Iquitos. On the way, stop off for a visit to the Rescue and Rehabilitation Center of River Mammals. Learn about the rescue work achieved by volunteers at the centre, then hear about manatees and feed these majestic, endangered animals.

Later, your tour comes to an end with a transfer to the airport for your onward flight. (B)

Tour Inclusions

  • Travel to Valparaiso for a guided discovery of the historic quarter and a funicular ride
  • Experience a stay at the only hotel located within Iguacu National Park, Brazil
  • Enjoy lunch and a Peruvian Paso horse show in Lima at a private hacienda
  • Visit Machu Picchu and set off on a locally guided exploration of the lost city of the Incas, one of the New Seven Wonders of the World

  • Services of an expert APT Tour Director and local guides
  • Prices include transfers, meals, accommodation, porterage, all internal flights within South America as per itinerary (including airport taxes which are subject to change) and gratuities

  • Enjoy the finest regional dining – a total of 43 meals

  • 18 nights' luxury stays
  • A four-night cruise aboard Delfin III through the Amazon rainforest in Peru

  • Itinerary, inclusions and pricing are subject to change
  • Flights to and from South America are not included
  • Service of an APT Tour Director on Amazon cruise is subject to minimum numbers
  • Atacama Desert extension available. Enquire for details
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Download Brochure

APT South America (2025) Brochure

APT South America (2025)

With APT, extraordinary moments become an everyday reality as you journey through the vibrant soul of South America and the pristine wilderness of Antarctica. Feel the thrill of discovery as you explore the colourful pulse of cities like Rio and Buenos Aires, stand in awe of majestic sites like Machu Picchu and Iguazú Falls, then cross into a world more of icy silence where penguins reign and whales dance across frigid waters. From the warmth of Latin flair to the crisp purity of the polar south, APT ensures every detail is taken care of - so you’re free to embrace each breathless, awe-inspiring moment.

Prices & Dates

There are currently no departures available on this cruise. Either it's the end of the season and new departures will be released shortly, or this itinerary has been changed and is not operating this season. Feel free to contact us for information about when next seasons dates will be released or click here to view general release dates for all destinations.

Note
Tour & cruises prices are per person. Prices shown have savings applied, are subject to availability and may be withdrawn at any time without notice. Pricing and trip details are correct at this point in time, however are subject to confirmation at the time of booking and are subject to change by APT. For cruise itineraries, cabin images are sourced from the cruise-line and should be treated as indicative only. Cabin inclusions, upholsteries and room layout may differ to the image(s) shown depending on the ship selected and your sailing dates.

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