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Crystal Cruises from San Diego

Start your journey from San Diego with 12 unique Crystal cruise itineraries to choose from. December and January are the most popular months to begin your cruise from San Diego and Crystal have 12 trips departing this season.
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12 Cruises (12 Departures)
12 Cruises (12 Departures)
Departures
Duration
9 Days
140 Days
Trip Styles
Price
$5,800pp
$122,200pp
Countries
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10 Day Roundtrip San Diego with Crystal Cruises
New ReleaseCruise

10 Days (9 Nights) San Diego to San Diego
Cruise Line: Crystal
Ship: Crystal Serenity
Departure: 30 December 2026
Visits: USA, Mexico
Oceanview
$9,900
Balcony
$12,100
Suite
$13,000
From (Per Person)
A$9,900
Per Person
View Trip
10 Day Roundtrip San Diego with Crystal Cruises
New ReleaseCruise

10 Days (9 Nights) San Diego to San Diego
Cruise Line: Crystal
Ship: Crystal Serenity
Departure: 21 December 2026
Visits: USA, Mexico
Oceanview
$9,200
Balcony
$11,200
Suite
$11,160
From (Per Person)
A$9,200
Per Person
View Trip
12 Day San Diego to Fuerte Amador with Crystal Cruises
New ReleaseCruise

12 Days (11 Nights) San Diego to Panama City
Cruise Line: Crystal
Ship: Crystal Serenity
Departure: 09 August 2027
Visits: USA, Mexico, El Salvador, Nicaragua, Costa Rica, Panama
Exclusive Savings
Oceanview
$7,490
Balcony
$9,900
Suite
$10,010
From (Per Person)
A$7,490
Save 710
Per Person
View Trip
9 Day San Diego to Vancouver with Crystal Cruises
New ReleaseCruise

9 Days (8 Nights) San Diego to Vancouver
Cruise Line: Crystal
Ship: Crystal Symphony
Departure: 25 June 2028
Visits: USA, Canada
Exclusive Savings
Oceanview
$5,830
Balcony
$7,900
Suite
$7,810
From (Per Person)
A$5,830
Save 570
Per Person
View Trip
13 Day San Diego to Guayaquil (Crystal Wellness Retreat Cruise) with Crystal Cruises
New ReleaseCruise

13 Days (12 Nights) San Diego to Guayaquil
Cruise Line: Crystal
Ship: Crystal Symphony
Departure: 24 August 2026
Visits: USA, Mexico, El Salvador, Costa Rica, Ecuador
Exclusive Savings
Oceanview
$7,745
Balcony
$10,700
Suite
$11,100
From (Per Person)
A$7,745
Save 1,155
Per Person
View Trip
19 Day San Diego to Vancouver with Crystal Cruises
New ReleaseCruise

19 Days (18 Nights) San Diego to Vancouver
Cruise Line: Crystal
Ship: Crystal Symphony
Departure: 25 June 2028
Visits: USA, Canada
Exclusive Savings
Oceanview
$13,710
Balcony
$19,000
Suite
$19,110
From (Per Person)
A$13,710
Save 1,290
Per Person
View Trip
16 Day San Diego to Callao (Lima) with Crystal Cruises
New ReleaseCruise

16 Days (15 Nights) San Diego to Lima
Cruise Line: Crystal
Ship: Crystal Serenity
Departure: 08 January 2027
Visits: USA, Mexico, El Salvador, Costa Rica, Ecuador, Peru
Oceanview
$12,000
Balcony
$14,000
Suite
$16,600
From (Per Person)
A$12,000
Per Person
View Trip
26 Day San Diego to New York with Crystal Cruises
New ReleaseCruise

26 Days (25 Nights) San Diego to New York
Cruise Line: Crystal
Ship: Crystal Serenity
Departure: 09 August 2027
Visits: USA, Mexico, El Salvador, Nicaragua +5 more, Costa Rica, Panama, Colombia, Jamaica, Cayman Islands
Exclusive Savings
Oceanview
$15,810
Balcony
$20,300
Suite
$20,670
From (Per Person)
A$15,810
Save 1,390
Per Person
View Trip
19 Day Roundtrip San Diego, California with Crystal Cruises
New ReleaseCruise

19 Days (18 Nights) San Diego to San Diego
Cruise Line: Crystal
Ship: Crystal Serenity
Departure: 21 December 2026
Visits: USA, Mexico
Oceanview
$19,200
Balcony
$23,300
Suite
$24,900
From (Per Person)
A$19,200
Per Person
View Trip
32 Day San Diego to Papeete with Crystal Cruises
New ReleaseCruise

32 Days (31 Nights) San Diego to Tahiti
Cruise Line: Crystal
Ship: Crystal Serenity
Departure: 08 January 2027
Visits: USA, Mexico, El Salvador, Costa Rica +5 more, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia
Oceanview
$25,400
Balcony
$30,600
Suite
$33,700
From (Per Person)
A$25,400
Per Person
View Trip
33 Day San Diego to New York City with Crystal Cruises
New ReleaseCruise

33 Days (32 Nights) San Diego to New York
Cruise Line: Crystal
Ship: Crystal Symphony
Departure: 24 August 2026
Visits: USA, Mexico, El Salvador, Costa Rica +12 more, Ecuador, Panama, Colombia, Dominican Republic, Puerto Rico, Saint Martin, Dominica, Barbados, Saint Lucia, Antigua and Barbuda, Virgin Islands, Turks and Caicos Islands
Exclusive Savings
Oceanview
$21,125
Balcony
$28,400
Suite
$29,080
From (Per Person)
A$21,125
Save 3,075
Per Person
View Trip
140 Day 2027 World Cruise: San Diego to Vancouver with Crystal Cruises
New ReleaseCruise

140 Days (139 Nights) San Diego to Vancouver
Cruise Line: Crystal
Ship: Crystal Serenity
Departure: 08 January 2027
Visits: USA, Mexico, El Salvador, Costa Rica +24 more, Ecuador, Peru, Chile, Pitcairn Islands, French Polynesia, American Samoa, Samoa, Fiji, Vanuatu, New Caledonia, New Zealand, Australia, Papua New Guinea, Indonesia, Singapore, Thailand, Vietnam, Brunei, Malaysia, Philippines, China, South Korea, Japan, Canada
Oceanview
$122,200
Balcony
$135,700
Suite
$153,100
From (Per Person)
A$122,200
Per Person
View Trip
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