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All South America Cruises

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331 Cruises (1,764 Cruise Departures)
10 Day Classic Galapagos: Central Eastern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 2,115
From 8,392
View Trip
7 Day South America with MSC Cruises
Cruise

7 Days (6 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 02 February 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$939
OCEANVIEW
$1,098
BALCONY
$1,306
SUITE
$2,424
From 939
View Trip
8 Day Galápagos – Central and East Islands aboard the Reina Silvia Voyager (Cruise Only) with G Adventures
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operated By: G Adventures
Departures: Jun 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Galapagos
Exclusive Deal
Save 2,446
From 6,756
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13 Day Valparaiso to Buenos Aires with Silversea
Cruise

13 Days (12 Nights) Valparaiso to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 09 February 2025
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$13,117
From 13,117
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 27 December 2024
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$3,239
OCEANVIEW
$3,388
BALCONY
$3,685
SUITE
$5,170
From 3,239
View Trip
15 Day Season Of Samba with Regent Seven Seas
Cruise

15 Days (14 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 03 December 2025
Countries Visited: Barbados, Saint Vincent, Trinidad and Tobago, French Guiana (+1 more), Brazil
Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$13,761
SUITE
$15,533
Save 8,269
From 13,761
View Trip
7 Day Galápagos - South & East Islands aboard the Yolita with G Adventures
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Jun 2025
Trip Styles: Group, Cruise, Wildlife
Countries Visited: Ecuador
Exclusive DealLast Minute Offer
Save 3,403
From 3,336
View Trip
25 Day Spirit of South America with Santiago and Galapagos Cruise with Globus
Tour + Cruise

25 Days Santiago to Guayaquil
Operated By: Globus
Departure: 12 October 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Exclusive Savings
Save 277
From 17,883
View Trip
10 Day Classic Galapagos: Central Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 2,115
From 8,392
View Trip
8 Day Pure Galapagos (Grand Daphne) with Intrepid Travel
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,804
From 7,038
View Trip
29 Day Best of South America with Amazon and Galapagos Cruises with APT
Tour + Cruise

29 Days Santiago to Guayaquil
Operated By: APT
Ships: Delfin III
Departure: 14 September 2024
Trip Styles: Coach, Group, Cruise, River Cruise, Island Hopping, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru (+2 more), Ecuador, Galapagos
Exclusive Savings
Save 604
From 34,791
View Trip
15 Day Peru & Galapagos by Yacht with Collette
Tour + Cruise

15 Days Lima to Quito
Operated By: Collette
Departures: Sep 2024 to Apr 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 192
From 11,213
View Trip
17 Day Edge Of The World Expedition with Regent Seven Seas
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 01 February 2026
Countries Visited: Chile, Argentina, Uruguay
Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$18,481
SUITE
$20,115
Save 8,169
From 18,481
View Trip
13 Day Chilean Fjords & Scenic Shores with Viking Cruises
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Nov 2024 to Oct 2025
Countries Visited: Chile, Argentina
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$13,855
SUITE
$19,795
Save 1,140
From 13,855
View Trip
23 Day Beauty At The End Of The World with Regent Seven Seas
Cruise

23 Days (22 Nights) Rio de Janeiro to Santiago
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 25 January 2025
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$15,501
SUITE
$16,980
Save 17,549
From 15,501
View Trip
30 Day Best of South America with Amazon and Galapagos Cruises with APT
Tour + Cruise

30 Days Santiago to Guayaquil
Operated By: APT
Ship: Delfin III
Departures: Apr 2025 to Sep 2025
Trip Styles: Coach, Group, Cruise, River Cruise, Island Hopping, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru (+2 more), Ecuador, Galapagos
Exclusive Deal
Save 2,739
From 39,656
View Trip
8 Day Lima to Panama City with Silversea
Cruise

8 Days (7 Nights) Lima to Panama City
Cruise Line: Silversea
Ship: Silver Ray
Departure: 04 January 2025
Countries Visited: Peru, Ecuador, Panama
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$4,158
From 4,158
View Trip
15 Day Amazon Delta & Coast Of Brazil with Seabourn
Cruise

15 Days (14 Nights) Manaus to Rio de Janeiro
Cruise Line: Seabourn
Ship: Venture
Departure: 21 October 2024
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$12,808
SUITE
$18,951
From 12,808
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Dec 2024 to Mar 2025
Countries Visited: Brazil
Early Booking OfferSave And Sail Offer
INSIDE
$1,208
OCEANVIEW
$1,436
BALCONY
$1,693
SUITE
$2,357
From 1,208
View Trip
17 Day Peru Splendors with Peru Amazon & Galapagos Cruise with Globus
Tour + Cruise

17 Days Lima to Guayaquil
Operated By: Globus
Departure: 04 December 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 187
From 11,922
View Trip
14 Day Patagonian Shores & Chilean Fjords with Viking Cruises
Cruise

14 Days (13 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Octantis
Departure: 11 November 2024
Countries Visited: Chile, Argentina
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$14,845
SUITE
$20,785
Save 1,150
From 14,845
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) São Paulo to São Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Nov 2024 to Mar 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$817
OCEANVIEW
$946
BALCONY
$1,095
SUITE
$1,540
From 817
View Trip
16 Day In-depth Patagonia & Chilean Fjords Expedition with Hurtigruten
Cruise

16 Days (15 Nights) Buenos Aires to Santiago
Cruise Line: Hurtigruten
Ship: MS Roald Amundsen
Departure: 20 March 2025
Countries Visited: Argentina, Chile
Exclusive Deal
INSIDE
-
OCEANVIEW
$16,975
BALCONY
$20,065
SUITE
$22,814
Save 4,697
From 16,975
View Trip
12 Day Lautoka to Tahiti with Silversea
Cruise

12 Days (11 Nights) Lautoka to Tahiti
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 29 September 2025
Countries Visited: Fiji, Cook Islands, Tonga, French Polynesia
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$22,473
BALCONY
$25,641
SUITE
$38,709
From 22,473
View Trip
17 Day Absolute Galapagos (Grand Daphne) with Intrepid Travel
Cruise

17 Days (16 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Sep 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 3,857
From 15,006
View Trip
5 Day South America with MSC Cruises
Cruise

5 Days (4 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departure: 20 March 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$817
OCEANVIEW
$946
BALCONY
$1,095
SUITE
$1,540
From 817
View Trip
13 Day Bounty Of Brazil with Oceania Cruises
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 10 January 2026
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
$6,185
OCEANVIEW
$6,947
BALCONY
$7,709
SUITE
$10,719
Save 2,045
From 6,185
View Trip
19 Day Legacy of the Incas with Galapagos Cruise with Globus
Tour + Cruise

19 Days Lima to Guayaquil
Operated By: Globus
Departure: 05 November 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save 257
From 15,866
View Trip
8 Day Galapagos: Wildlife Wonderland with Tauck
Cruise

8 Days (7 Nights) Quito to Guayaquil
Operated By: Tauck
Departures: Jun 2025 to Aug 2025
Trip Styles: Group, Cruise, Family, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
From 12,140
View Trip
4 Day South America with MSC Cruises
Cruise

4 Days (3 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Mar 2025 to Apr 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$668
OCEANVIEW
$767
BALCONY
$876
SUITE
$1,242
From 668
View Trip
Results: 31-60 of 331

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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Panama Cruises Patagonia Cruises Peru Cruises Portugal Cruises South America Cruises South Georgia Island Cruises Spain Cruises Uruguay Cruises

Travel Styles

Coach Tours Locally Guided Tours Luxury Cruises Short Cruise Breaks Wildlife Tours

Cities

Barcelona Bridgetown Buenos Aires Colon Lima Lisbon Manaus Marseille Papeete Quito Rio de Janeiro San Antonio Santiago Santiago Sao Paulo

Routes

Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to San Antonio Cruises from Buenos Aires to Buenos Aires Cruises from Dover to Dover Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Copenhagen Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Fort Lauderdale Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to New York Cruises from New York to New York Cruises from New York to London Cruises from Papeete to Papeete Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Juan to San Juan Cruises from Santiago to Santiago Cruises from Sao Paulo to Sao Paulo

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from France to Brazil Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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