Home > Cruises > Central America Cruises > Cruises from Panama to USA

Cruises from Panama to USA

Are you looking for a cruise from Panama to USA? February is the most popular month to cruise between Panama and USA and there are 28 departures available from eight of the world's leading cruise lines.
Filter Results
Departures
Show More...
Duration
8 Days
32 Days
Start & End Cities
Ship Size
Ship Features
Operators
Show More...
Price
$1,900pp
$16,995pp
Countries
Show More...
Filter Results
23 Cruises (28 Cruise Departures)
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise
 (4)

11 Days (10 Nights) Panama City to Fort Lauderdale
Cruise Line: Viking Cruises
Ship: Viking Mars
Departures: Oct 2024 to Dec 2025
Countries Visited: Panama, Costa Rica, Honduras, Belize (+2 more), Mexico, USA
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$5,638
SUITE
$8,905
Save 1,074
From 5,638
View Trip
12 Day Caribbean Quest Voyage with Azamara Cruises
Cruise
 (1)

12 Days (11 Nights) Panama City to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 15 March 2026
Countries Visited: Panama, Colombia, Aruba, Bonaire (+3 more), Curacao, Dominican Republic, USA
INSIDE
$3,963
OCEANVIEW
$4,884
BALCONY
$5,803
SUITE
$6,723
From 3,963
View Trip
12 Day Classic Panama Canal with Oceania Cruises
Cruise
 (2)

12 Days (11 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 18 February 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+4 more), Bonaire, Jamaica, Bahamas, USA
Exclusive Deal
INSIDE
$5,931
OCEANVIEW
$6,386
BALCONY
$8,831
SUITE
$12,217
Save 2,039
From 5,931
View Trip
11 Day Captivating Panama Canal with Oceania Cruises
Cruise
 (2)

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 02 April 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+3 more), Bonaire, Jamaica, USA
Exclusive Deal
INSIDE
$5,147
OCEANVIEW
$5,533
BALCONY
$7,751
SUITE
$10,285
Save 2,033
From 5,147
View Trip
10 Day Panama Canal - Panama City with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Panama City to Miami
Ship: Norwegian Gem
Departure: 11 December 2024
Countries Visited: Panama, Costa Rica, Jamaica, Cayman Islands (+3 more), Mexico, Bahamas, USA
INSIDE
$1,988
OCEANVIEW
$2,263
BALCONY
$3,332
SUITE
$3,516
From 1,988
View Trip
11 Day Classic Canal & Tropics with Oceania Cruises
Cruise

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 04 April 2026
Countries Visited: Panama, Colombia, Curacao, Aruba (+3 more), Jamaica, Cayman Islands, USA
Exclusive Deal
INSIDE
$5,026
OCEANVIEW
$5,482
BALCONY
$7,927
SUITE
$10,927
Save 2,034
From 5,026
View Trip
10 Day Panama Canal Voyage with Azamara Cruises
Cruise

10 Days (9 Nights) Panama City to Miami
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 13 December 2024
Countries Visited: Panama, Costa Rica, Honduras, Guatemala (+2 more), Mexico, USA
INSIDE
$3,180
OCEANVIEW
$3,361
BALCONY
$4,138
SUITE
$5,689
From 3,180
View Trip
12 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Panama City to Miami
Ship: Norwegian Jade
Departure: 09 February 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+4 more), Saint Kitts and Nevis, Virgin Islands, Dominican Republic, USA
Exclusive Solo Offer
INSIDE
$2,364
OCEANVIEW
$2,884
BALCONY
$4,551
SUITE
$4,705
From 2,364
View Trip
11 Day Tropical Tastes Of The Riviera with Regent Seven Seas
Cruise

11 Days (10 Nights) Panama City to Los Angeles
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 15 January 2026
Countries Visited: Panama, Costa Rica, Nicaragua, Mexico (+1 more), USA
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$9,618
SUITE
$10,143
Save 6,132
From 9,618
View Trip
11 Day Panama Canal Repositioning Cruise with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Panama City to Tampa
Ship: Norwegian Jade
Departure: 19 January 2025
Countries Visited: Panama, Colombia, Jamaica, Cayman Islands (+4 more), Honduras, Belize, Mexico, USA
INSIDE
$2,267
OCEANVIEW
$2,528
BALCONY
$3,920
SUITE
$4,195
From 2,267
View Trip
11 Day Canal & Coral Isles with Oceania Cruises
Cruise

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 24 April 2026
Countries Visited: Panama, Colombia, Costa Rica, Honduras (+2 more), Mexico, USA
Exclusive Deal
INSIDE
$5,026
OCEANVIEW
$5,482
BALCONY
$7,927
SUITE
$10,927
Save 2,034
From 5,026
View Trip
32 Day San Antonio To Southampton with Cunard
Cruise

32 Days (31 Nights) Santiago to London
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 25 February 2025
Countries Visited: Chile, Peru, Ecuador, Panama (+6 more), Aruba, Bahamas, USA, Bermuda, Portugal, England
INSIDE
$7,237
OCEANVIEW
$8,524
BALCONY
$11,098
SUITE
$25,552
From 7,237
View Trip
12 Day Panama Canal - Panama City with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Panama City to Galveston
Ship: Norwegian Jade
Departure: 26 January 2026
Countries Visited: Panama, Colombia, Jamaica, Cayman Islands (+4 more), Honduras, Belize, Mexico, USA
Exclusive Solo Offer
INSIDE
$2,827
OCEANVIEW
$3,362
BALCONY
$4,739
SUITE
$5,244
From 2,827
View Trip
8 Day A Journey Traversing The Panama Canal with Explora Journeys
Cruise

8 Days (7 Nights) Panama City to Miami
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 24 May 2024
Countries Visited: Panama, Colombia, USA
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,583
SUITE
$7,672
From 5,593
View Trip
11 Day Panama Canal - Panama City with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Panama City to Miami
Ship: Norwegian Jade
Departure: 10 November 2025
Countries Visited: Panama, Colombia, Jamaica, Cayman Islands (+4 more), Honduras, Belize, Mexico, USA
INSIDE
$2,687
OCEANVIEW
$3,146
BALCONY
$4,369
SUITE
$4,752
From 2,687
View Trip
18 Day Panama & Scenic South America with Viking Cruises
Cruise

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Mar 2025 to Mar 2025
Countries Visited: Chile, Peru, Ecuador, Panama (+2 more), Mexico, USA
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$15,340
SUITE
$22,765
Save 1,160
From 15,340
View Trip
14 Day Panama Canal - Panama City with Norwegian Cruise Line
Cruise

14 Days (13 Nights) Panama City to New York
Ship: Norwegian Jade
Departure: 22 December 2025
Countries Visited: Panama, Colombia, Aruba, Curacao (+5 more), Saint Lucia, Saint Kitts and Nevis, Virgin Islands, Dominican Republic, USA
INSIDE
$4,008
OCEANVIEW
$4,774
BALCONY
$6,685
SUITE
$7,832
From 4,008
View Trip
18 Day San Antonio To Fort Lauderdale with Cunard
Cruise

18 Days (17 Nights) Santiago to Fort Lauderdale
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 25 February 2025
Countries Visited: Chile, Peru, Ecuador, Panama (+3 more), Aruba, Bahamas, USA
INSIDE
$4,658
OCEANVIEW
$5,450
BALCONY
$7,232
SUITE
$16,340
From 4,658
View Trip
8 Day Panama City to Fort Lauderdale with Silversea
Cruise

8 Days (7 Nights) Panama City to Fort Lauderdale
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 20 May 2025
Countries Visited: Panama, Colombia, USA
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$4,158
BALCONY
$5,049
SUITE
-
From 4,158
View Trip
10 Day Panama City to Fort Lauderdale with Silversea
Cruise

10 Days (9 Nights) Panama City to Fort Lauderdale
Cruise Line: Silversea
Ship: Silver Ray
Departure: 11 January 2025
Countries Visited: Aruba, Colombia, Panama, USA
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$5,989
From 5,989
View Trip
12 Day Panama Canal - Panama City with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Panama City to Miami
Ship: Norwegian Jade
Departure: 16 February 2026
Countries Visited: Panama, Colombia, Aruba, Saint Lucia (+4 more), Saint Kitts and Nevis, Virgin Islands, Dominican Republic, USA
INSIDE
$2,788
OCEANVIEW
$3,323
BALCONY
$4,821
SUITE
$5,205
From 2,788
View Trip
12 Day Panama City to Los Angeles with Silversea
Cruise

12 Days (11 Nights) Panama City to Los Angeles
Cruise Line: Silversea
Ship: Silver Shadow
Departure: 24 December 2024
Countries Visited: Panama, Costa Rica, Mexico, USA
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$7,227
BALCONY
-
SUITE
-
From 7,227
View Trip
13 Day Pacific Pathways with Oceania Cruises
Cruise

13 Days (12 Nights) Colon to Los Angeles
Cruise Line: Oceania Cruises
Ship: Oceania Regatta
Departure: 14 November 2025
Countries Visited: Panama, Costa Rica, Nicaragua, Guatemala (+2 more), Mexico, USA
Exclusive Deal
INSIDE
$5,977
OCEANVIEW
$6,511
BALCONY
$9,412
SUITE
$13,115
Save 2,043
From 5,977
View Trip
Results: 23 results

No Results found. Try changing your search filters.




Cruises found! Scroll up to view

South & Central America Cruises

Central America Cruises South America Cruises Mexico Cruises Galapagos Cruises Bermunda Cruises Bahamas Cruises Caribbean Cruises Amazon Cruises Patagonia Cruises Cape Horn Cruises Falkland Island Cruises Panama Cruises

Travel Styles

Luxury Cruises

Countries

Belize Colombia Costa Rica Ecuador Honduras Mexico Panama Peru USA

Cities

Colon Panama City Santiago

Routes

Cruises from Panama City to Miami

Country Routes

Cruises from Panama to USA Cruises from USA to England

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

Central America Tours

All Central America Tours Belize Tours Costa Rica Tours Guatemala Tours Mexico Tours Panama Tours

© 2010-2024. Global Journeys. You're viewing our site in Australian dollars.

    

About Us | View Your Booking | Terms & Conditions | Site Map | We're Hiring!

Global Journeys Pty Ltd. Member of The Australian Travel Industry Association (AITA) & ATAS Travel Accredited (No. A11351).

Travel Industry Associations