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All South America Cruises

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331 Cruises (1,764 Cruise Departures)
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Dec 2024 to Mar 2025
Countries Visited: Uruguay, Brazil, Argentina
Early Booking OfferSave And Sail Offer
INSIDE
$1,526
OCEANVIEW
$1,734
BALCONY
$2,130
SUITE
-
From 1,526
View Trip
25 Day Palms To Penguins with Oceania Cruises
Cruise

25 Days (24 Nights) Rio de Janeiro to San Antonio
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 22 January 2026
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
Exclusive Deal
INSIDE
$11,801
OCEANVIEW
$13,405
BALCONY
$15,009
SUITE
$21,493
Save 2,089
From 11,801
View Trip
15 Day San Cristóbal to San Cristóbal with Silversea
Cruise

15 Days (14 Nights) Guayaquil to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Oct 2025 to Dec 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$30,987
SUITE
$47,421
From 30,987
View Trip
7 Day Independent Galapagos Cruise Aboard the Galapagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operated By: Globus
Departures: Aug 2024 to Mar 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 140
From 6,892
View Trip
13 Day Ushuaia to Valparaiso with Silversea
Cruise

13 Days (12 Nights) Ushuaia to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 16 March 2026
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$10,692
BALCONY
$12,771
SUITE
$28,611
From 10,692
View Trip
15 Day San Cristóbal to San Cristóbal with Silversea
Cruise

15 Days (14 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jul 2024 to Jul 2025
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$19,404
SUITE
$75,339
Save 350
From 19,404
View Trip
8 Day South America with MSC Cruises
Cruise

8 Days (7 Nights) Sao Paulo to Sao Paulo
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: Jan 2025 to Mar 2025
Countries Visited: Brazil, Uruguay, Argentina
Save And Sail OfferEarly Booking Offer
INSIDE
$1,208
OCEANVIEW
$1,436
BALCONY
$1,693
SUITE
$2,357
From 1,208
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From 19,700
View Trip
8 Day Galapagos Southern with Celebrity Cruises
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Cruise Line: Celebrity Cruises
Ship: Celebrity Xpedition
Departures: Jun 2024 to Dec 2025
Countries Visited: Galapagos
Exclusive Deal
INSIDE
-
OCEANVIEW
$7,892
BALCONY
-
SUITE
$9,132
Save 4,749
From 7,892
View Trip
17 Day Complete Galápagos - Eden with G Adventures
Cruise

17 Days (16 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jun 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 3,078
From 11,721
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Quito
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jun 2024 to Aug 2025
Countries Visited: Ecuador, Galapagos
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$13,414
SUITE
$22,374
Save 636
From 13,414
View Trip
15 Day Cape Horn & Strait of Magellan with Princess
Cruise

15 Days (14 Nights) Buenos Aires to Santiago
Cruise Line: Princess
Ship: Sapphire Princess
Departures: Feb 2025 to Mar 2025
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
INSIDE
$2,938
OCEANVIEW
$3,039
BALCONY
$5,611
SUITE
$6,093
From 2,938
View Trip
22 Day The Complete Amazon Experience & Coast Of Brazil with Seabourn
Cruise

22 Days (21 Nights) Manaus to Rio de Janeiro
Cruise Line: Seabourn
Ship: Venture
Departure: 21 October 2025
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$24,065
SUITE
$41,821
From 24,065
View Trip
7 Day South America with MSC Cruises
Cruise

7 Days (6 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Dec 2024 to Feb 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$939
OCEANVIEW
$1,098
BALCONY
$1,306
SUITE
$2,424
From 939
View Trip
8 Day Galápagos - South & East Islands aboard the Eden with G Adventures
Cruise

8 Days (7 Nights) Quito to Quito
Operated By: G Adventures
Departures: Jun 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 1,601
From 4,618
View Trip
15 Day Patagonia & Argentina Cruise with Celebrity Cruises
Cruise

15 Days (14 Nights) Buenos Aires to Buenos Aires
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Dec 2025 to Feb 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Exclusive DealExclusive Offer
INSIDE
$2,883
OCEANVIEW
$3,815
BALCONY
$3,630
SUITE
$9,664
Save 4,560
From 2,883
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) San Cristobal Island to San Cristobal Island
Cruise Line: Silversea
Ship: Silver Origin
Departures: Feb 2026 to Mar 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$20,592
SUITE
$30,591
From 20,592
View Trip
12 Day Wonders of the Galápagos & Machu Picchu: Eastern Islands Route with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Apr 2025 to Oct 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
From 27,245
View Trip
9 Day Lima to Valparaiso with Silversea
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Ray
Departure: 01 February 2025
Countries Visited: Chile, Peru
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$7,672
From 7,672
View Trip
9 Day Lima to Valparaiso with Silversea
Cruise

9 Days (8 Nights) Lima to Valparaiso
Cruise Line: Silversea
Ship: Silver Wind
Departure: 10 November 2024
Countries Visited: Peru, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$7,326
BALCONY
$8,712
SUITE
-
From 7,326
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Jan 2025 to Feb 2025
Countries Visited: Uruguay, Brazil, Argentina
Save And Sail Offer
INSIDE
$1,845
OCEANVIEW
$2,112
BALCONY
$2,548
SUITE
-
From 1,845
View Trip
13 Day Ushuaia to Valparaiso with Silversea
Cruise

13 Days (12 Nights) Ushuaia to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 19 March 2025
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
$9,405
BALCONY
$11,385
SUITE
-
From 9,405
View Trip
7 Day Galapagos Express - Central, South & East Islands aboard the Archipel I with Explore!
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Explore!
Departures: May 2024 to Dec 2025
Trip Styles: Small Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 155
From 7,428
View Trip
8 Day Galápagos - West & Central Islands aboard the Reina Silvia Voyager (Cruise Only) with G Adventures
Cruise

8 Days (7 Nights) Baltra Island to Baltra Island
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 2,446
From 7,053
View Trip
13 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 16 December 2025
Countries Visited: Argentina, Uruguay, Brazil
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$11,187
BALCONY
$12,276
SUITE
$20,889
From 11,187
View Trip
9 Day Galapagos Voyage: Pirates & Darwin - Premium Adventure with Exodus Adventure Travels
New ReleaseCruise

9 Days (8 Nights) Quito to Quito
Departures: May 2024 to Dec 2024
Trip Styles: Group, Cruise, Island Hopping, Wildlife
Countries Visited: Ecuador
Exclusive Savings
Save 326
From 15,974
View Trip
10 Day South America with MSC Cruises
Cruise

10 Days (9 Nights) Montevideo to Montevideo
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 29 December 2024
Countries Visited: Uruguay, Brazil, Argentina
Save And Sail Offer
INSIDE
$2,597
OCEANVIEW
-
BALCONY
$3,290
SUITE
-
From 2,597
View Trip
14 Day Argentina & the Chilean Fjords with Viking Cruises
Cruise

14 Days (13 Nights) Buenos Aires to Santiago
Cruise Line: Viking Cruises
Ships: Viking Octantis, Viking Polaris
Departures: Feb 2025 to Mar 2026
Countries Visited: Argentina, Chile
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$13,657
SUITE
$19,795
Save 1,140
From 13,657
View Trip
21 Day Lima to Buenos Aires with Silversea
Cruise

21 Days (20 Nights) Lima to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 01 February 2025
Countries Visited: Argentina, Chile, Peru
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$25,344
From 25,344
View Trip
9 Day South America with MSC Cruises
Cruise

9 Days (8 Nights) Buenos Aires to Buenos Aires
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departures: Dec 2024 to Mar 2025
Countries Visited: Argentina, Uruguay, Brazil
Early Booking OfferSave And Sail Offer
INSIDE
$1,526
OCEANVIEW
$1,734
BALCONY
$2,021
SUITE
$3,487
From 1,526
View Trip
Results: 121-150 of 331

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South & Central America Cruises

Amazon Cruises Antarctica Cruises Argentina Cruises Bahamas Cruises Barbados Cruises Bermunda Cruises Brazil Cruises Cape Horn Cruises Caribbean Cruises Central America Cruises Chile Cruises Ecuador Cruises Falkland Island Cruises Falkland Islands Cruises France Cruises Galapagos Cruises Mexico Cruises Morocco Cruises Panama Cruises Panama Cruises Patagonia Cruises Peru Cruises Portugal Cruises South America Cruises South Georgia Island Cruises Spain Cruises Uruguay Cruises

Travel Styles

Coach Tours Locally Guided Tours Luxury Cruises Short Cruise Breaks Wildlife Tours

Cities

Barcelona Bridgetown Buenos Aires Colon Lima Lisbon Manaus Marseille Papeete Quito Rio de Janeiro San Antonio Santiago Santiago Sao Paulo

Routes

Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to San Antonio Cruises from Buenos Aires to Buenos Aires Cruises from Dover to Dover Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to London Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Copenhagen Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Fort Lauderdale Cruises from Los Angeles to Los Angeles Cruises from Marseille to Marseille Cruises from Miami to San Juan Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Bridgetown Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to New York Cruises from New York to New York Cruises from New York to London Cruises from Papeete to Papeete Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Barcelona Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Juan to San Juan Cruises from Santiago to Santiago Cruises from Sao Paulo to Sao Paulo

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from France to Brazil Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises Hurtigruten South America Cruises MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking Central America Cruises Viking South America Cruises

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