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Cruises from Spain to Italy

Are you looking for a cruise from Spain to Italy? August, April and September are the most popular months to cruise between Spain and Italy and there are 215 departures available from sixteen of the world's leading cruise lines.
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112 Cruises (215 Cruise Departures)
8 Day Mediterranean with France & Italy with Princess
Cruise

8 Days (7 Nights) Barcelona to Naples
Cruise Line: Princess
Ship: Sun Princess
Departures: Jun 2025 to Sep 2025
Countries Visited: Spain, Gibraltar, France, Italy
INSIDE
$1,746
OCEANVIEW
$2,132
BALCONY
$2,409
SUITE
$2,825
From 1,746
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 11 July 2024
Countries Visited: Spain, Italy, France
Exclusive DealExclusive Offer
INSIDE
-
OCEANVIEW
$2,204
BALCONY
$2,522
SUITE
$7,015
Save 2,823
From 2,029
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4 Day MSC Grand Voyages with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Genoa
Cruise Line: MSC Cruises
Ship: MSC Magnifica
Departure: 28 November 2024
Countries Visited: Spain, Italy
Exclusive Deal
INSIDE
$470
OCEANVIEW
$569
BALCONY
$678
SUITE
$1,093
From 470
View Trip
23 Day Mediterranean Magic & Tyrrhenian Treasures with Seabourn
Cruise

23 Days (22 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 31 August 2024
Countries Visited: Spain, Sardinia, France, Italy (+4 more), Monaco, Sicily, Malta, Corsica
More Moments On Us Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$21,504
SUITE
-
From 21,504
View Trip
12 Day Barcelona to Rome with Silversea
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 26 April 2025
Countries Visited: Spain, France, Monaco, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,553
From 14,553
View Trip
8 Day France And Italy with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 16 June 2025
Countries Visited: Spain, France, Sardinia, Sicily (+1 more), Italy
INSIDE
$1,338
OCEANVIEW
$1,556
BALCONY
$1,783
SUITE
$3,744
From 1,338
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Malaga to Genoa
Cruise Line: MSC Cruises
Ship: MSC Poesia
Departure: 10 November 2024
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$669
SUITE
-
From 669
View Trip
6 Day France & Italy Cruise with Royal Caribbean
Cruise

6 Days (5 Nights) Barcelona to Ravenna
Cruise Line: Royal Caribbean
Ship: Explorer of the Seas
Departure: 12 May 2025
Countries Visited: Spain, Corsica, Italy, Sicily
Exclusive Deal
INSIDE
$1,533
OCEANVIEW
$1,889
BALCONY
$2,075
SUITE
$3,272
Save 581
From 1,327
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departures: Jul 2024 to Sep 2024
Countries Visited: Spain, France, Corsica, Italy
Exclusive Deal
INSIDE
$2,362
OCEANVIEW
$2,635
BALCONY
$3,842
SUITE
$5,147
Save 1,703
From 2,362
View Trip
15 Day Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 August 2025
Countries Visited: Spain, Malta, Italy, Croatia (+2 more), Montenegro, Greece
INSIDE
$2,766
OCEANVIEW
$3,212
BALCONY
$3,657
SUITE
$7,667
From 2,766
View Trip
9 Day Mediterranean Marvels & Matches: Monte Carlo Masters with Seabourn
Cruise

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Venture
Departure: 05 April 2025
Countries Visited: Spain, France, Monaco, Italy
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$8,844
SUITE
$21,298
From 8,844
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Naples
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departure: 23 April 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
$530
OCEANVIEW
$659
BALCONY
$758
SUITE
$1,104
From 530
View Trip
8 Day France And Italy with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departures: Aug 2024 to Sep 2024
Countries Visited: Spain, Sardinia, Corsica, Sicily (+1 more), Italy
INSIDE
$2,130
OCEANVIEW
$2,328
BALCONY
$2,001
SUITE
$4,120
From 2,001
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+6 more), Viking Saturn, Viking Sky, Viking Star, Viking Vela, Viking Venus, Viking Vesta
Departures: Sep 2024 to Jul 2026
Countries Visited: Spain, France, Monaco, Italy
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$4,450
SUITE
$6,925
Save 1,279
From 4,450
View Trip
22 Day Adriatic And Western Mediterranean with Cunard
Cruise

22 Days (21 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 22 June 2026
Countries Visited: Spain, Corsica, Sicily, Italy (+4 more), Greece, Montenegro, Croatia, Malta
INSIDE
$4,857
OCEANVIEW
$5,253
BALCONY
$6,095
SUITE
$12,876
From 4,857
View Trip
9 Day A Journey To Elegant Enclaves On Old European Shores with Explora Journeys
Cruise

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 11 August 2024
Countries Visited: Spain, France, Italy
Unique EscapesExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$8,331
SUITE
$10,182
From 8,331
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departures: Jun 2025 to Sep 2025
Countries Visited: Spain, France, Corsica, Italy
Exclusive Deal
INSIDE
$1,443
OCEANVIEW
$2,003
BALCONY
$2,539
SUITE
$3,232
Save 621
From 1,282
View Trip
13 Day Barcelona to Rome with Silversea
Cruise

13 Days (12 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 18 May 2025
Countries Visited: Spain, France, Monaco, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,315
From 18,315
View Trip
8 Day Spain, France & Italy Cruise with Celebrity Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 17 August 2024
Countries Visited: Spain, France, Italy
Exclusive DealExclusive Offer
INSIDE
$1,833
OCEANVIEW
$2,056
BALCONY
$2,972
SUITE
$5,586
Save 2,373
From 1,772
View Trip
12 Day Barcelona to Civitavecchia with Virgin Voyages
Cruise

12 Days (11 Nights) Barcelona to Rome
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 03 November 2024
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sardinia
INSIDE
$3,276
OCEANVIEW
$3,694
BALCONY
$4,204
SUITE
-
From 3,276
View Trip
15 Day France, Italy And Adriatic with Cunard
Cruise

15 Days (14 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 08 September 2025
Countries Visited: Spain, Sardinia, Corsica, Sicily (+4 more), Italy, Greece, Montenegro, Croatia
INSIDE
$2,627
OCEANVIEW
$2,855
BALCONY
$3,568
SUITE
$7,043
From 2,627
View Trip
10 Day Italian Riviera & France with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departure: 08 August 2024
Countries Visited: Spain, Italy, France
Exclusive DealExclusive Offer
INSIDE
$1,914
OCEANVIEW
$2,434
BALCONY
$2,365
SUITE
$7,071
Save 2,700
From 1,902
View Trip
Results: 91-112 of 112

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