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Spain Cruises Starting In September 2025

If you're looking at joining a cruise to Spain in September 2025, we have 42 unique cruise itineraries and 668 departures available, operated by twelve of the world's leading cruise lines departing in September.
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Departures (September 2025)
< August 2025 October 2025 >
Duration
8 Days
17 Days
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$100pp
$29,040pp
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42 Cruises (668 Cruise Departures)
9 Day Cruising Southern Spain and Portugal - with Smithsonian Journeys with Ponant
Cruise
 (2)

9 Days (8 Nights) Barcelona to Lisbon
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 16 September 2025
Countries Visited: Spain, Portugal
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,439
SUITE
$15,917
Save 181
From 9,439
View Trip
9 Day Iberian Shores with Ponant
Cruise
 (2)

9 Days (8 Nights) Lisbon to Barcelona
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 24 September 2025
Countries Visited: Portugal, Spain
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$6,568
SUITE
$12,311
Save 122
From 6,568
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9 Day Civitavecchia to Barcelona with Silversea
Cruise

9 Days (8 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 23 September 2025
Countries Visited: Italy, Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$12,078
From 12,078
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Oasis of the Seas
Departures: Jun 2024 to Oct 2025
Countries Visited: Spain, Italy
Exclusive Deal
INSIDE
$1,577
OCEANVIEW
$2,103
BALCONY
$2,135
SUITE
$3,049
Save 4,264
From 1,389
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8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Oasis of the Seas
Departures: Jul 2024 to Oct 2025
Countries Visited: Italy, Spain
Exclusive Deal
INSIDE
$1,940
OCEANVIEW
$2,438
BALCONY
$2,464
SUITE
$3,515
Save 1,622
From 1,636
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Oasis of the Seas
Departures: May 2024 to Oct 2025
Countries Visited: Spain, France, Italy
Exclusive Deal
INSIDE
$1,686
OCEANVIEW
$2,266
BALCONY
$2,279
SUITE
$3,069
Save 1,438
From 1,484
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8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2024 to Oct 2025
Countries Visited: Italy, Spain, France
Mutiple Deals Available
INSIDE
$1,465
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,475
From 1,465
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+8 more), Viking Neptune, Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vela, Viking Venus, Viking Vesta
Departures: Sep 2024 to Sep 2026
Countries Visited: Italy, Monaco, France, Spain
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$4,450
SUITE
$6,925
Save 1,171
From 4,450
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8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Magnifica
Departures: May 2024 to Sep 2025
Countries Visited: Spain, Italy, France
Best Deal OfferEarly Booking Offer
INSIDE
$1,296
OCEANVIEW
$1,484
BALCONY
$1,672
SUITE
$2,514
From 1,296
View Trip
8 Day Spain & France Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) London to London
Cruise Line: Royal Caribbean
Ship: Independence of the Seas
Departure: 22 September 2025
Countries Visited: England, France, Spain
Exclusive Deal
INSIDE
$1,661
OCEANVIEW
$2,146
BALCONY
$2,622
SUITE
$3,508
Save 683
From 1,452
View Trip
10 Day Europe - Western Mediterranean with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Ships: Norwegian Breakaway, Norwegian Escape
Departures: Nov 2024 to Sep 2025
Countries Visited: Spain, Italy, France
INSIDE
$2,250
OCEANVIEW
$2,613
BALCONY
$2,690
SUITE
$2,843
From 2,250
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Magnifica
Departures: May 2024 to Sep 2025
Countries Visited: France, Spain, Italy
Mutiple Deals Available
INSIDE
$1,266
OCEANVIEW
$1,494
BALCONY
$1,673
SUITE
$2,405
From 1,266
View Trip
12 Day Canaries & Portugal Cruise with Celebrity Cruises
Cruise

12 Days (11 Nights) London to London
Cruise Line: Celebrity Cruises
Ship: Celebrity Apex
Departure: 27 September 2025
Countries Visited: England, Portugal, Spain
Exclusive Offer
INSIDE
$2,614
OCEANVIEW
$2,602
BALCONY
$3,520
SUITE
$8,720
Save 3,437
From 2,602
View Trip
8 Day A Journey From Barcelona To Civitavecchia with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Sep 2025
Countries Visited: Spain, France, Italy
Unique EscapesPenthouse Dream Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,846
SUITE
$7,108
From 5,846
View Trip
8 Day Western Mediterranean with Cunard
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 01 September 2025
Countries Visited: Italy, France, Spain
INSIDE
$1,427
OCEANVIEW
$1,645
BALCONY
$1,873
SUITE
$3,833
From 1,427
View Trip
10 Day Spanish Flair Cruise with Royal Caribbean
Cruise

10 Days (9 Nights) London to London
Cruise Line: Royal Caribbean
Ships: Anthem of the Seas, Independence of the Seas
Departures: Aug 2024 to Sep 2025
Countries Visited: England, Spain, Portugal
Exclusive Deal
INSIDE
$2,275
OCEANVIEW
$2,890
BALCONY
$3,585
SUITE
$4,758
Save 3,270
From 1,998
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2024 to Oct 2025
Countries Visited: Italy, Spain, France
Mutiple Deals Available
INSIDE
$1,465
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,475
From 1,465
View Trip
11 Day Iberian Embrace with Oceania Cruises
Cruise

11 Days (10 Nights) Bilbao to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 04 September 2025
Countries Visited: Spain, Portugal, Morocco
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$7,617
SUITE
$10,458
Save 2,063
From 7,617
View Trip
8 Day Iconic Western Mediterranean with Viking Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+6 more), Viking Saturn, Viking Sky, Viking Star, Viking Vela, Viking Venus, Viking Vesta
Departures: Sep 2024 to Jul 2026
Countries Visited: Spain, France, Monaco, Italy
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$4,450
SUITE
$6,925
Save 1,178
From 4,450
View Trip
14 Day Mediterranean with P&O Cruises Worldwide
Cruise

14 Days (13 Nights) London to London
Ship: Arvia
Departures: Sep 2025 to Oct 2026
Countries Visited: England, Spain, France
INSIDE
$2,041
OCEANVIEW
$2,512
BALCONY
$2,977
SUITE
$4,153
From 2,041
View Trip
10 Day Italian Riviera & France Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jun 2025 to Sep 2025
Countries Visited: Italy, France, Spain
Exclusive Offer
INSIDE
$2,357
OCEANVIEW
$2,919
BALCONY
$3,203
SUITE
$8,190
Save 3,391
From 2,357
View Trip
10 Day Spain, Portugal & Morocco Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: Jul 2024 to Oct 2025
Countries Visited: Spain, Portugal, Morocco
Exclusive DealExclusive Offer
INSIDE
$2,174
OCEANVIEW
$2,679
BALCONY
$2,923
SUITE
$7,850
Save 10,799
From 2,174
View Trip
15 Day Northern Europe with MSC Cruises
Cruise

15 Days (14 Nights) London to London
Cruise Line: MSC Cruises
Ship: MSC Virtuosa
Departures: Jul 2024 to Jul 2026
Countries Visited: England, Spain, Portugal
Best Deal OfferEarly Booking Offer
INSIDE
$1,859
OCEANVIEW
$2,018
BALCONY
$2,453
SUITE
$4,542
From 1,859
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ships: MSC Fantasia, MSC Magnifica
Departures: May 2024 to Sep 2025
Countries Visited: Italy, France, Spain
Mutiple Deals Available
INSIDE
$1,266
OCEANVIEW
$1,494
BALCONY
$1,673
SUITE
$2,405
From 1,266
View Trip
8 Day Istanbul And Greek Islands with Cunard
Cruise

8 Days (7 Nights) Barcelona to Istanbul
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 29 September 2025
Countries Visited: Spain, Greece, Turkey
INSIDE
$1,585
OCEANVIEW
$1,783
BALCONY
$2,031
SUITE
$4,258
From 1,585
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palma de Mallorca to Palma de Mallorca
Cruise Line: MSC Cruises
Ship: MSC Seaview
Departures: May 2024 to Oct 2025
Countries Visited: Spain, France, Italy
Mutiple Deals Available
INSIDE
$1,465
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,475
From 1,465
View Trip
17 Day Escapades In Iberia with Regent Seven Seas
Cruise

17 Days (16 Nights) Paris to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 09 September 2025
Countries Visited: France, Spain, Portugal
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$22,036
SUITE
$24,916
Save 7,004
From 22,036
View Trip
11 Day Flamenco & Jaleo with Regent Seven Seas
Cruise

11 Days (10 Nights) Lisbon to Barcelona
Cruise Line: Regent Seven Seas
Ship: Seven Seas Voyager
Departure: 14 September 2025
Countries Visited: Portugal, Spain, France
Exclusive Solo OfferExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,872
SUITE
$13,386
Save 7,548
From 10,872
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ships: Allure of the Seas, Oasis of the Seas
Departures: Jun 2024 to Oct 2025
Countries Visited: Italy, Spain, France
Exclusive Deal
INSIDE
$2,125
OCEANVIEW
$2,574
BALCONY
$2,566
SUITE
$3,674
Save 1,283
From 1,833
View Trip
9 Day Monte Carlo to Rome with Silversea
Cruise

9 Days (8 Nights) Monte Carlo to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 07 September 2025
Countries Visited: Monaco, France, Spain, Italy
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$11,286
From 11,286
View Trip
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Trip Lengths

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Departure Months

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Cities

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Routes

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Country Routes

Brazil to Spain England to Spain France to Spain Greece to Spain Italy to Spain Malta to Spain Monaco to Spain Portugal to Spain Spain to United Arab Emirates Spain to Monaco Spain to Turkey Spain to Brazil Spain to France Spain to Greece Spain to Italy Spain to Malta Spain to Portugal Spain to USA Spain to England Turkey to Spain USA to Spain

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