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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 249 unique cruise itineraries to Sicily, departing from Athens, Barcelona, Florence, Genoa, Istanbul and more. October is the most popular month to cruise to Sicily and we have over 1,364 departures available from nineteen of the world's leading cruise lines.
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29 Days
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249 Cruises (1,364 Cruise Departures)
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Livorno to Livorno
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaside
Departures: May 2024 to Oct 2025
Countries Visited: Italy, France, Spain, Tunisia (+1 more), Sicily
Mutiple Deals Available
INSIDE
$1,445
OCEANVIEW
$1,652
BALCONY
$1,890
SUITE
$2,474
From 1,445
View Trip
13 Day Greek Isles, Italy & Turkey with Celebrity Cruises
Cruise

13 Days (12 Nights) Rome to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 14 October 2024
Countries Visited: Italy, Greece, Turkey, Sicily (+1 more), Spain
Exclusive Offer
INSIDE
$3,105
OCEANVIEW
$3,902
BALCONY
$4,939
SUITE
$11,265
Save 3,910
From 3,105
View Trip
11 Day Greece, Italy & Spain with Celebrity Cruises
Cruise

11 Days (10 Nights) Athens to Barcelona
Cruise Line: Celebrity Cruises
Ship: Celebrity Silhouette
Departure: 21 October 2024
Countries Visited: Greece, Turkey, Sicily, Italy (+1 more), Spain
Exclusive Offer
INSIDE
$2,753
OCEANVIEW
$3,050
BALCONY
$3,255
SUITE
$9,493
Save 3,365
From 2,753
View Trip
8 Day Western Mediterranean with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 08 September 2025
Countries Visited: Spain, Sardinia, Corsica, Sicily (+1 more), Italy
INSIDE
$1,427
OCEANVIEW
$1,645
BALCONY
$1,873
SUITE
$3,833
From 1,427
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaside
Departures: May 2024 to Oct 2025
Countries Visited: France, Spain, Tunisia, Sicily (+1 more), Italy
Mutiple Deals Available
INSIDE
$1,464
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,474
From 1,464
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Naples to Naples
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaside
Departures: May 2024 to Oct 2025
Countries Visited: Italy, France, Spain, Tunisia (+1 more), Sicily
Mutiple Deals Available
INSIDE
$1,464
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,474
From 1,464
View Trip
8 Day Italy And Adriatic with Cunard
Cruise

8 Days (7 Nights) Barcelona to Trieste
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 27 July 2026
Countries Visited: Spain, Italy, Sicily, Greece (+1 more), Montenegro
INSIDE
$1,783
OCEANVIEW
$1,981
BALCONY
$2,179
SUITE
$4,951
From 1,783
View Trip
12 Day Grand Western Mediterranean with Princess
Cruise

12 Days (11 Nights) Rome to Barcelona
Cruise Line: Princess
Ship: Sun Princess
Departure: 29 July 2025
Countries Visited: Italy, Sicily, France, Gibraltar (+1 more), Spain
INSIDE
$2,982
OCEANVIEW
$3,576
BALCONY
$4,814
SUITE
$5,893
From 2,982
View Trip
14 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

14 Days (13 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 20 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+1 more), Malta
INSIDE
$1,693
OCEANVIEW
$2,087
BALCONY
$2,817
SUITE
$4,598
From 1,693
View Trip
17 Day An Extended Journey Unlocking Mediterranean Myths with Explora Journeys
Cruise

17 Days (16 Nights) Barcelona to Athens
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 19 June 2024
Countries Visited: Spain, Sicily, Malta, Greece (+1 more), Turkey
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$14,008
SUITE
$16,236
From 14,008
View Trip
11 Day Greco-roman Exploration with Regent Seven Seas
Cruise

11 Days (10 Nights) Rome to Athens
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 01 August 2025
Countries Visited: Italy, Sicily, Malta, Turkey (+1 more), Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,316
SUITE
$14,861
Save 6,174
From 13,316
View Trip
8 Day A Journey From Civitavecchia To Barcelona with Explora Journeys
Cruise

8 Days (7 Nights) Rome to Barcelona
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Sep 2025
Countries Visited: Italy, Sicily, Tunisia, Sardinia (+1 more), Spain
Unique EscapesPenthouse Dream Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$5,197
SUITE
$6,341
From 5,197
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaside
Departures: May 2024 to Oct 2025
Countries Visited: Spain, Tunisia, Sicily, Italy (+1 more), France
Mutiple Deals Available
INSIDE
$1,464
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,474
From 1,464
View Trip
11 Day Islands of the Mediterranean: Spain to Malta with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Barcelona to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 25 April 2026
Countries Visited: Spain, Corsica, Sardinia, Sicily (+1 more), Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,489
BALCONY
-
SUITE
$14,449
Save 2,606
From 10,489
View Trip
15 Day Mediterranean with P&O Cruises Worldwide
Cruise

15 Days (14 Nights) Valletta to Valletta
Ship: Azura
Departure: 01 August 2024
Countries Visited: Malta, Italy, Greece, Sicily (+1 more), Corsica
INSIDE
-
OCEANVIEW
$5,315
BALCONY
$6,194
SUITE
$12,116
From 5,315
View Trip
11 Day Greece, Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 16 May 2025
Countries Visited: Italy, Greece, Croatia, Montenegro (+1 more), Sicily
Exclusive Offer
INSIDE
$3,354
OCEANVIEW
$3,849
BALCONY
$4,368
SUITE
$9,452
Save 3,841
From 3,354
View Trip
8 Day Mediterranean with Greece & Italy with Princess
Cruise

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Princess
Ships: Sun Princess, Sun Princess
Departures: Jul 2024 to Oct 2026
Countries Visited: Greece, Montenegro, Sicily, Italy (+1 more), Spain
INSIDE
$2,296
OCEANVIEW
$2,524
BALCONY
$2,913
SUITE
$3,376
From 2,296
View Trip
15 Day Mediterranean & Italian Sojourn with Viking Cruises
Cruise

15 Days (14 Nights) Venice to Barcelona
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+4 more), Viking Saturn, Viking Vela, Viking Venus, Viking Vesta
Departures: May 2025 to Sep 2026
Countries Visited: Italy, Croatia, Sicily, Monaco (+2 more), France, Spain
Discover More Sale
INSIDE
-
OCEANVIEW
-
BALCONY
$11,677
SUITE
$18,805
Save 1,950
From 11,677
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Oct 2024 to Apr 2025
Countries Visited: Italy, Sicily, Tunisia, Spain (+1 more), France
Early Booking OfferSave And Sail Offer
INSIDE
$1,167
OCEANVIEW
$1,346
BALCONY
$1,474
SUITE
$2,029
From 1,167
View Trip
12 Day Venice to Rome with Silversea
Cruise

12 Days (11 Nights) Venice to Rome
Cruise Line: Silversea
Ship: Silver Moon
Departure: 20 September 2024
Countries Visited: Italy, Croatia, Montenegro, Malta (+1 more), Sicily
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$15,543
BALCONY
$16,236
SUITE
-
From 15,543
View Trip
18 Day Discover the Jewels of French & Italian Rivieras with Emerald Cruises
New ReleaseCruise

18 Days (17 Nights) Nice to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 12 October 2024
Countries Visited: France, Italy, Corsica, Sicily (+1 more), Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$21,508
Save 7,217
From 21,508
View Trip
15 Day Western Mediterranean with Cunard
Cruise

15 Days (14 Nights) Rome to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 10 August 2026
Countries Visited: Italy, Spain, France, Sardinia (+1 more), Sicily
INSIDE
$3,172
OCEANVIEW
$3,518
BALCONY
$3,964
SUITE
$8,518
From 3,172
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Marseille to Marseille
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Nov 2024 to Apr 2025
Countries Visited: France, Italy, Sicily, Tunisia (+1 more), Spain
Early Booking OfferSave And Sail Offer
INSIDE
$1,068
OCEANVIEW
$1,296
BALCONY
$1,425
SUITE
$2,029
From 1,068
View Trip
11 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Rome to Rome
Ship: Norwegian Epic
Departure: 08 June 2024
Countries Visited: Italy, Greece, Malta, Sicily (+1 more), France
INSIDE
$2,094
OCEANVIEW
-
BALCONY
$3,211
SUITE
-
From 2,094
View Trip
13 Day European Explorer with Princess
Cruise

13 Days (12 Nights) London to Rome
Cruise Line: Princess
Ship: Caribbean Princess
Departure: 08 October 2024
Countries Visited: England, Spain, Malta, Sicily (+1 more), Italy
INSIDE
$1,976
OCEANVIEW
$2,079
BALCONY
$2,846
SUITE
$3,739
From 1,976
View Trip
13 Day Canary Islands And Mediterranean with P&O Cruises Worldwide
Cruise

13 Days (12 Nights) Santa Cruz de Tenerife to Valletta
Ship: Azura
Departure: 21 March 2026
Countries Visited: Spain, Gibraltar, Italy, Sicily (+1 more), Malta
INSIDE
$1,515
OCEANVIEW
$1,839
BALCONY
$2,599
SUITE
-
From 1,515
View Trip
10 Day Valletta to Nice with Silversea
Cruise

10 Days (9 Nights) Valletta to Nice
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 18 July 2025
Countries Visited: Malta, Sicily, Sardinia, Italy (+1 more), France
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$11,880
BALCONY
$14,454
SUITE
$20,790
From 11,880
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaside
Departures: May 2024 to Oct 2025
Countries Visited: Sicily, Italy, France, Spain (+1 more), Tunisia
Mutiple Deals Available
INSIDE
$1,464
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,474
From 1,464
View Trip
8 Day Greek Isles, Italy, & France: European Jewels with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Rome to Venice
Ship: Norwegian Escape
Departure: 03 October 2024
Countries Visited: Italy, Sicily, Malta, Greece (+1 more), Croatia
INSIDE
$4,019
OCEANVIEW
$4,554
BALCONY
$4,815
SUITE
$5,396
From 4,019
View Trip
11 Day Greece, Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 10 October 2025
Countries Visited: Italy, Greece, Croatia, Montenegro (+1 more), Sicily
Exclusive Offer
INSIDE
$3,106
OCEANVIEW
$3,856
BALCONY
$4,599
SUITE
$9,754
Save 3,668
From 3,106
View Trip
Results: 181-210 of 249

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