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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 247 unique cruise itineraries to Sicily, departing from Antalya, Athens, Barcelona, Florence, Genoa and more. October is the most popular month to cruise to Sicily and we have over 1,360 departures available from nineteen of the world's leading cruise lines.
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247 Cruises (1,360 Cruise Departures)
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Messina
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 31 December 2024
Countries Visited: Sicily, Malta, Spain, France (+1 more), Italy
Exclusive Deal
INSIDE
$2,187
OCEANVIEW
$2,405
BALCONY
$2,543
SUITE
-
From 2,187
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Genoa to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Nov 2024 to Dec 2024
Countries Visited: Italy, Sicily, Malta, Spain (+1 more), France
Save And Sail OfferEarly Booking Drinks Package
INSIDE
$1,296
OCEANVIEW
$1,524
BALCONY
$1,643
SUITE
$2,039
From 1,296
View Trip
11 Day Europe - Classic Mediterranean with Norwegian Cruise Line
Cruise
 (1)

11 Days (10 Nights) Athens to Rome
Ship: Norwegian Viva
Departure: 19 October 2024
Countries Visited: Greece, Turkey, Sicily, Italy (+1 more), France
INSIDE
$7,056
OCEANVIEW
$5,449
BALCONY
$7,056
SUITE
$8,264
From 5,449
View Trip
10 Day Mediterranean Highlights Cruise with Royal Caribbean
Cruise
 (2)

10 Days (9 Nights) Barcelona to Athens
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 21 May 2025
Countries Visited: Spain, Sicily, Malta, Greece (+1 more), Turkey
Exclusive Deal
INSIDE
$2,628
OCEANVIEW
$2,444
BALCONY
$3,255
SUITE
$7,194
Save 995
From 2,235
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Messina to Messina
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: May 2024 to Oct 2025
Countries Visited: Sicily, Malta, Spain, France (+1 more), Italy
Mutiple Deals Available
INSIDE
$1,801
OCEANVIEW
$2,069
BALCONY
$2,267
SUITE
$3,543
From 1,801
View Trip
11 Day Around Italy's Boot: Palermo with Holland America
Cruise
 (1)

11 Days (10 Nights) Venice to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departure: 19 June 2025
Countries Visited: Italy, Croatia, Montenegro, Greece (+1 more), Sicily
Have It All Offer
INSIDE
$3,322
OCEANVIEW
$3,767
BALCONY
$4,559
SUITE
$6,094
From 3,322
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Naples
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 07 April 2025
Countries Visited: Italy, Sicily, Malta, Spain (+1 more), France
Save And Sail Offer
INSIDE
$1,583
OCEANVIEW
$1,811
BALCONY
$1,940
SUITE
$3,019
From 1,583
View Trip
11 Day Renaissance Triumphs with Oceania Cruises
Cruise
 (1)

11 Days (10 Nights) Rome to Barcelona
Cruise Line: Oceania Cruises
Ship: Oceania Riviera
Departure: 04 November 2024
Countries Visited: Italy, Sicily, Malta, France (+1 more), Spain
Exclusive DealSingles Special Offer
INSIDE
$4,418
OCEANVIEW
$5,557
BALCONY
$6,398
SUITE
$9,091
Save 2,032
From 4,418
View Trip
8 Day Malta & Aegean Jewels with Holland America
Cruise
 (1)

8 Days (7 Nights) Rome to Athens
Cruise Line: Holland America
Ship: Oosterdam
Departure: 01 September 2024
Countries Visited: Italy, Sicily, Malta, Greece (+1 more), Turkey
Have It All Offer
INSIDE
$1,984
OCEANVIEW
$2,182
BALCONY
$2,504
SUITE
$3,454
From 1,984
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Nov 2024 to Dec 2024
Countries Visited: Sicily, Malta, Spain, France (+1 more), Italy
Save And Sail Offer
INSIDE
$1,296
OCEANVIEW
$1,524
BALCONY
$1,692
SUITE
-
From 1,296
View Trip
29 Day Lands Of Legends, Eternal Cities & Greek Isles with Holland America
Cruise
 (2)

29 Days (28 Nights) Athens to Athens
Cruise Line: Holland America
Ship: Nieuw Statendam
Departure: 05 October 2024
Countries Visited: Greece, Malta, Tunisia, Sicily (+1 more), Turkey
Have It All Offer
INSIDE
$6,710
OCEANVIEW
$7,463
BALCONY
$8,186
SUITE
$11,383
From 6,710
View Trip
12 Day Mediterranean Springtime in France and Italy with Ponant
Cruise
 (1)

12 Days (11 Nights) Nice to Nice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 10 May 2025
Countries Visited: France, Italy, Sicily, Sardinia (+1 more), Corsica
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$11,296
SUITE
$21,302
Save 214
From 11,296
View Trip
6 Day Mediterranean with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Messina to Genoa
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departure: 08 April 2025
Countries Visited: Sicily, Malta, Spain, France (+1 more), Italy
Exclusive Deal
INSIDE
$853
OCEANVIEW
$1,032
BALCONY
$1,289
SUITE
-
From 853
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rome to Rome
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Jan 2025 to Mar 2025
Countries Visited: Italy, Sicily, Malta, Spain (+1 more), France
Save And Sail Offer
INSIDE
$1,316
OCEANVIEW
$1,544
BALCONY
$1,662
SUITE
$2,058
From 1,316
View Trip
8 Day Mediterranean with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ship: MSC World Europa
Departures: Jan 2025 to Apr 2025
Countries Visited: Spain, France, Italy, Sicily (+1 more), Malta
Save And Sail Offer
INSIDE
$1,316
OCEANVIEW
$1,544
BALCONY
$1,662
SUITE
$2,454
From 1,316
View Trip
9 Day Italy & Greece with Celebrity Cruises
Cruise
 (1)

9 Days (8 Nights) Barcelona to Athens
Cruise Line: Celebrity Cruises
Ship: Celebrity Infinity
Departure: 26 January 2025
Countries Visited: Spain, Italy, Sicily, Turkey (+1 more), Greece
Exclusive Offer
INSIDE
$1,323
OCEANVIEW
$1,522
BALCONY
$2,253
SUITE
$6,598
Save 2,092
From 1,323
View Trip
15 Day Lands Of Legends & Eternal Cities with Holland America
Cruise
 (2)

15 Days (14 Nights) Athens to Athens
Cruise Line: Holland America
Ship: Nieuw Statendam
Departure: 05 October 2024
Countries Visited: Greece, Malta, Tunisia, Sicily (+1 more), Turkey
Have It All Offer
INSIDE
$3,325
OCEANVIEW
$3,721
BALCONY
$4,286
SUITE
$6,177
From 3,325
View Trip
11 Day Malta, Sicily & Aegean Jewels: Naples & Hidden Gems with Holland America
Cruise
 (1)

11 Days (10 Nights) Rome to Athens
Cruise Line: Holland America
Ship: Oosterdam
Departure: 29 May 2025
Countries Visited: Italy, Sicily, Malta, Montenegro (+1 more), Greece
Have It All Offer
INSIDE
$3,322
OCEANVIEW
$3,520
BALCONY
$4,411
SUITE
$5,896
From 3,322
View Trip
18 Day Discover the Jewels of French & Italian Rivieras with Emerald Cruises
New ReleaseCruise

18 Days (17 Nights) Nice to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 12 October 2024
Countries Visited: France, Italy, Corsica, Sicily (+1 more), Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$21,508
Save 7,217
From 21,508
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Valencia to Venice
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 27 March 2025
Countries Visited: Spain, Sicily, Greece, Italy (+1 more), Croatia
Early Booking Offer
INSIDE
$1,405
OCEANVIEW
$1,751
BALCONY
$2,682
SUITE
$4,088
From 1,405
View Trip
10 Day Canary Islands And Madeira with MSC Cruises
Cruise

10 Days (9 Nights) Santa Cruz de Tenerife to Bari
Cruise Line: MSC Cruises
Ship: MSC Opera
Departure: 23 March 2025
Countries Visited: Spain, Morocco, Sicily, Greece (+1 more), Italy
Save And Sail Offer
INSIDE
$1,748
OCEANVIEW
$2,194
BALCONY
$3,382
SUITE
$5,213
From 1,748
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Palermo to Palermo
Cruise Line: MSC Cruises
Ship: MSC Fantasia
Departures: Nov 2024 to Apr 2025
Countries Visited: Sicily, Tunisia, Spain, France (+1 more), Italy
Early Booking Offer
INSIDE
$1,118
OCEANVIEW
$1,346
BALCONY
$1,474
SUITE
$2,187
From 1,118
View Trip
8 Day Western Mediterranean with Cunard
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 08 September 2025
Countries Visited: Spain, Sardinia, Corsica, Sicily (+1 more), Italy
INSIDE
$1,427
OCEANVIEW
$1,645
BALCONY
$1,873
SUITE
$3,833
From 1,427
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Naples to Naples
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaside
Departures: Jun 2024 to Oct 2025
Countries Visited: Italy, France, Spain, Tunisia (+1 more), Sicily
Mutiple Deals Available
INSIDE
$1,464
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,474
From 1,464
View Trip
12 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Rome to Rome
Ship: Norwegian Epic
Departures: Oct 2024 to Oct 2025
Countries Visited: Italy, Greece, Malta, Sicily (+1 more), France
Exclusive Solo Offer
INSIDE
$2,753
OCEANVIEW
-
BALCONY
$4,329
SUITE
$4,818
From 2,753
View Trip
17 Day Civitavecchia to Barcelona with Silversea
Cruise

17 Days (16 Nights) Rome to Barcelona
Cruise Line: Silversea
Ship: Silver Ray
Departure: 15 September 2025
Countries Visited: Italy, Sicily, Tunisia, France (+1 more), Spain
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$18,909
From 18,909
View Trip
11 Day Greece, Italy & Croatia Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Rome to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 19 September 2025
Countries Visited: Italy, Greece, Croatia, Montenegro (+1 more), Sicily
Exclusive Offer
INSIDE
$3,308
OCEANVIEW
$4,020
BALCONY
$4,854
SUITE
$9,604
Save 3,747
From 3,308
View Trip
8 Day Mediterranean with MSC Cruises
Cruise

8 Days (7 Nights) Barcelona to Barcelona
Cruise Line: MSC Cruises
Ships: MSC Grandiosa, MSC Seaside
Departures: May 2024 to Oct 2025
Countries Visited: Spain, Tunisia, Sicily, Italy (+1 more), France
Mutiple Deals Available
INSIDE
$1,464
OCEANVIEW
$1,692
BALCONY
$1,890
SUITE
$2,474
From 1,464
View Trip
17 Day An Extended Journey Unlocking Mediterranean Myths with Explora Journeys
Cruise

17 Days (16 Nights) Barcelona to Athens
Cruise Line: Explora Journeys
Ship: Explora I
Departure: 19 June 2024
Countries Visited: Spain, Sicily, Malta, Greece (+1 more), Turkey
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$14,008
SUITE
$16,236
From 14,008
View Trip
11 Day The Mediterranean: in the Footsteps of Great Civilizations with Ponant
Cruise

11 Days (10 Nights) Antalya to Valletta
Cruise Line: Ponant
Ship: L'Austral
Departure: 19 May 2024
Countries Visited: Turkey, Greece, Italy, Sicily (+1 more), Malta
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,864
SUITE
$22,927
Save 186
From 9,864
View Trip
Results: 151-180 of 247

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