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South America Tours Starting In September 2025

If you're looking at joining a tour through South America in September 2025, we have 174 unique tours and small group adventures with 10,604 departures from the world's leading tour operators departing in September.
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Departures (September 2025)
< August 2025 October 2025 >
Duration
3 Days
65 Days
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Price
$500pp
$68,875pp
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174 Tours (10,604 Tour Departures)
20 Day Brazil, Argentina & Chile Unveiled with Peru with Cosmos
Tour
 (2)

20 Days Rio de Janeiro to Lima
Operated By: Cosmos
Departures: Feb 2025 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
From 8,081
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19 Day Ultimate South America with Cosmos
Tour
 (13)

19 Days Rio de Janeiro to Lima
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Peru
Exclusive Savings
From 7,789
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20 Day Highlights of South America with Travelmarvel
Tour
 (4)

20 Days Santiago to Lima
Operated By: Travelmarvel
Departures: Sep 2024 to Sep 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru
Exclusive Deal
Save 989
From 12,206
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12 Day Legacy of the Incas with Globus
Tour
 (3)

12 Days Lima to Lima
Operated By: Globus
Departures: Nov 2024 to Sep 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Savings
Save 148
From 7,991
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22 Day South American Odyssey with Peru with Globus
Tour
 (3)

22 Days Rio de Janeiro to Lima
Operated By: Globus
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
Save 242
From 13,417
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23 Day Ultimate South America with Brazil's Amazon with Cosmos
Tour
 (3)

23 Days Manaus to Lima
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Peru
Exclusive Savings
From 9,973
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30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From 16,620
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8 Day Highlights of Peru with Trafalgar
Tour
 (2)

8 Days Lima to Lima
Operated By: Trafalgar
Departures: Jul 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Deal
Save 522
From 4,944
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11 Day Mysteries of the Inca Empire with Cosmos
Tour
 (2)

11 Days Lima to Lima
Operated By: Cosmos
Departures: Aug 2024 to Sep 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Mothers Day Sale
Save 158
From 4,589
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19 Day Mysteries of the Inca Empire with Peru's Amazon & Arequipa and Colca Canyon with Cosmos
Tour
 (2)

19 Days Lima to Lima
Operated By: Cosmos
Departures: Oct 2024 to Sep 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Savings
Save 125
From 7,951
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8 Day Peru Splendours with Globus
Tour
 (2)

8 Days Lima to Lima
Operated By: Globus
Departures: Aug 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Savings
Save 89
From 4,716
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26 Day South American Odyssey with Brazil's Amazon & Peru with Globus
Tour
 (2)

26 Days Manaus to Lima
Operated By: Globus
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
Save 282
From 15,790
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21 Day Absolute Peru (Inca Trail) with G Adventures
Tour
 (1)

21 Days Lima to Lima
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group, Walking & Hiking, Inca Trail
Countries Visited: Peru
Exclusive Deal
Save 1,462
From 5,282
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18 Day Andes, Iguassu & Beyond with G Adventures
Tour
 (1)

18 Days Santiago to Rio de Janeiro
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Chile, Brazil
Exclusive Savings
Save 131
From 5,487
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24 Day Brazil, Argentina & Chile Unveiled with Peru and Brazil's Amazon with Cosmos
Tour
 (1)

24 Days Manaus to Lima
Operated By: Cosmos
Departures: Jan 2025 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
From 10,239
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9 Day Ecuador: Amazon, Hot Springs & Volcanoes with G Adventures
Tour
 (1)

9 Days Quito to Quito
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Ecuador
Exclusive Deal
Save 746
From 2,153
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9 Day Galápagos Island Hopping with Quito with G Adventures
Tour
 (1)

9 Days Quito to Quito
Operated By: G Adventures
Departures: Jun 2024 to Dec 2025
Trip Styles: Adventure, Group, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 903
From 3,326
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23 Day Grand South America with Luxury Gold
Tour
 (1)

23 Days Lima to Rio de Janeiro
Operated By: Luxury Gold
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru, Chile, Argentina, Brazil
Founder's Collection
Save 494
From 27,248
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9 Day Iguassu & Beyond with G Adventures
Tour
 (1)

9 Days Buenos Aires to Rio de Janeiro
Operated By: G Adventures
Departures: Jun 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Brazil
Exclusive Savings
Save 76
From 3,135
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11 Day In the Footsteps of the Incas with Trafalgar
Tour
 (1)

11 Days Lima to Lima
Operated By: Trafalgar
Departures: Jun 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Savings
Save 143
From 8,007
View Trip
12 Day South American Getaway with Santiago with Globus
Tour
 (1)

12 Days Rio de Janeiro to Santiago
Operated By: Globus
Departures: Jul 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile
Exclusive Savings
Save 125
From 6,826
View Trip
23 Day South American Odyssey with Brazil Amazon & Easter Island with Globus
Tour
 (1)

23 Days Manaus to Santiago
Operated By: Globus
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Easter Island, Chile
Exclusive Savings
Save 258
From 15,268
View Trip
26 Day Ultimate South America with a Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From 14,462
View Trip
12 Day Classic South America with Luxury Gold
Tour

12 Days Santiago to Rio de Janeiro
Operated By: Luxury Gold
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Chile, Argentina, Brazil
Exclusive Savings
Save 298
From 15,729
View Trip
16 Day Peruvian Amazon & Machu Picchu Exploration with Uniworld River Cruises
River Cruise

16 Days Lima to Lima
Ships: Aria Amazon
Departures: Aug 2024 to Nov 2025
Rivers: Amazon
Countries Visited: Peru
Earlybird Saving
Save 1,212
From 20,987
View Trip
27 Day Ultimate South America with Brazil's Amazon, Arequipa & the Colca Canyon with Cosmos
Tour

27 Days Manaus to Lima
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Peru
Exclusive Savings
From 11,395
View Trip
26 Day Ultimate South America with a Santiago Stopover, Arequipa & the Colca Canyon with Cosmos
Tour

26 Days Santiago to Lima
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Chile, Brazil, Argentina, Peru
Exclusive Savings
From 10,831
View Trip
10 Day The Inca Journey with G Adventures
Tour

10 Days Lima to Lima
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Peru
Exclusive Deal
Save 807
From 2,961
View Trip
6 Day Bolivian Magic with Contiki
Tour

6 Days La Paz to La Paz
Operated By: Contiki
Departures: Aug 2024 to Feb 2026
Trip Styles: Coach, Group, 18-30's, Short Break, Scenic
Countries Visited: Bolivia
Exclusive Savings
Save 287
From 1,788
View Trip
8 Day Machu Picchu Adventure with G Adventures
Tour

8 Days Lima to Lima
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Peru
Exclusive Deal
Save 499
From 1,821
View Trip
Results: 1-30 of 174

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