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South America Luxury Cruises

Explore the best luxury cruises around South America. Choose from 113 unique cruise itineraries from 8 leading cruise lines. January is the most popular month to join a luxury cruise around South America with 236 departures starting between June 2024 and March 2026.
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113 Cruises (236 Cruise Departures)
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Quito
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jun 2024 to Aug 2025
Countries Visited: Ecuador, Galapagos
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$13,414
SUITE
$22,374
Save 636
From 13,414
View Trip
15 Day Amazon Delta & Coast Of Brazil with Seabourn
Cruise

15 Days (14 Nights) Manaus to Rio de Janeiro
Cruise Line: Seabourn
Ship: Venture
Departure: 21 October 2024
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$12,808
SUITE
$18,951
From 12,808
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Jun 2024 to Mar 2026
Countries Visited: Ecuador, Galapagos
Mutiple Deals Available
INSIDE
-
OCEANVIEW
-
BALCONY
$15,840
SUITE
$18,513
From 15,840
View Trip
23 Day Beauty At The End Of The World with Regent Seven Seas
Cruise

23 Days (22 Nights) Rio de Janeiro to Santiago
Cruise Line: Regent Seven Seas
Ship: Seven Seas Mariner
Departure: 25 January 2025
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
International OfferExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$15,501
SUITE
$16,980
Save 17,549
From 15,501
View Trip
21 Day Rio De Janeiro to Bridgetown with Silversea
Cruise

21 Days (20 Nights) Rio de Janeiro to Bridgetown
Cruise Line: Silversea
Ship: Silver Ray
Departure: 03 March 2025
Countries Visited: Brazil, French Guiana, Barbados
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$21,978
From 21,978
View Trip
17 Day Edge Of The World Expedition with Regent Seven Seas
Cruise

17 Days (16 Nights) Santiago to Buenos Aires
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 01 February 2026
Countries Visited: Chile, Argentina, Uruguay
Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$18,481
SUITE
$20,115
Save 8,169
From 18,481
View Trip
12 Day Crossing the Equator: Barbados to Brazil with Scenic
Cruise

12 Days (11 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 05 November 2024
Countries Visited: Brazil, French Guiana, Barbados
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,960
SUITE
$10,207
Save 10,570
From 6,960
View Trip
15 Day Wild Guianas To The Amazon Basin with Seabourn
Cruise

15 Days (14 Nights) Bridgetown to Manaus
Cruise Line: Seabourn
Ship: Venture
Departure: 07 October 2024
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$18,357
SUITE
$34,851
From 18,357
View Trip
8 Day Lima to Panama City with Silversea
Cruise

8 Days (7 Nights) Lima to Panama City
Cruise Line: Silversea
Ship: Silver Ray
Departure: 04 January 2025
Countries Visited: Peru, Ecuador, Panama
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$4,158
From 4,158
View Trip
12 Day Wonders of the Galápagos & Machu Picchu: Northern Islands Route with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Feb 2025 to Nov 2025
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
From 26,465
View Trip
12 Day Wonders of the Galápagos & Machu Picchu with Abercrombie & Kent
New ReleaseTour + Cruise

12 Days Guayaquil to Lima
Operated By: Abercrombie & Kent
Departures: Aug 2024 to Nov 2024
Trip Styles: Coach, Small Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru
Exclusive Solo Offer
From 26,490
View Trip
11 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

11 Days (10 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Ray
Departure: 21 February 2025
Countries Visited: Argentina, Uruguay, Brazil
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,157
From 14,157
View Trip
19 Day Cape Horn Encounter with Oceania Cruises
Cruise

19 Days (18 Nights) San Antonio to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 06 March 2025
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Cabin Upgrade Offer
INSIDE
$8,646
OCEANVIEW
$9,794
BALCONY
$9,794
SUITE
$12,160
From 8,646
View Trip
11 Day Brazilian Rhythms with Oceania Cruises
Cruise

11 Days (10 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Oceania Cruises
Ship: Oceania Vista
Departure: 24 January 2026
Countries Visited: Brazil, Uruguay, Argentina
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,420
SUITE
$8,955
Save 2,050
From 6,420
View Trip
13 Day Ushuaia to Valparaiso with Silversea
Cruise

13 Days (12 Nights) Ushuaia to Valparaiso
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 16 March 2026
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$12,771
SUITE
$28,611
From 12,771
View Trip
13 Day Rhythms of the Brazilian Coastline with Scenic
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 22 March 2025
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$14,449
SUITE
$18,706
Save 5,646
From 14,449
View Trip
13 Day Buenos Aires to Rio De Janeiro with Silversea
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Silversea
Ship: Silver Whisper
Departure: 16 December 2025
Countries Visited: Argentina, Uruguay, Brazil
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$11,187
BALCONY
$12,276
SUITE
$20,889
From 11,187
View Trip
13 Day Valparaiso to Puerto Williams with Silversea
Cruise

13 Days (12 Nights) Valparaiso to Santiago
Cruise Line: Silversea
Ship: Silver Cloud
Departure: 07 November 2024
Countries Visited: Argentina, Chile
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
$10,593
BALCONY
$12,276
SUITE
$19,800
From 10,593
View Trip
15 Day Season Of Samba with Regent Seven Seas
Cruise

15 Days (14 Nights) Bridgetown to Rio de Janeiro
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 03 December 2025
Countries Visited: Barbados, Saint Vincent, Trinidad and Tobago, French Guiana (+1 more), Brazil
Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$13,761
SUITE
$15,533
Save 8,269
From 13,761
View Trip
12 Day Rhythms of the Brazilian Coastline with Scenic
Cruise

12 Days (11 Nights) Rio de Janeiro to Buenos Aires
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departures: Nov 2024 to Oct 2025
Countries Visited: Brazil, Uruguay, Argentina
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,623
SUITE
$14,365
Save 7,607
From 10,623
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Guayaquil
Operated By: Tauck
Departures: Jun 2024 to Oct 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From 24,330
View Trip
8 Day San Cristóbal to San Cristóbal with Silversea
Cruise

8 Days (7 Nights) Quito to Guayaquil
Cruise Line: Silversea
Ship: Silver Origin
Departures: Apr 2025 to Feb 2026
Countries Visited: Ecuador, Galapagos
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
$17,919
SUITE
$26,334
From 17,919
View Trip
13 Day Amazon Delta & Coast Of Brazil with Seabourn
Cruise

13 Days (12 Nights) Manaus to Rio de Janeiro
Cruise Line: Seabourn
Ship: Venture
Departure: 30 October 2025
Countries Visited: Brazil
The Sail Away Event
INSIDE
-
OCEANVIEW
-
BALCONY
$12,402
SUITE
$17,115
From 12,402
View Trip
25 Day Palms To Penguins with Oceania Cruises
Cruise

25 Days (24 Nights) Rio de Janeiro to San Antonio
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 22 January 2026
Countries Visited: Brazil, Uruguay, Argentina, Falkland Islands (+1 more), Chile
Exclusive Deal
INSIDE
$11,801
OCEANVIEW
$13,405
BALCONY
$15,009
SUITE
$21,493
Save 2,089
From 11,801
View Trip
13 Day Tango & Samba Celebration with Oceania Cruises
Cruise

13 Days (12 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 14 January 2025
Countries Visited: Argentina, Uruguay, Brazil
Cabin Upgrade Offer
INSIDE
$6,283
OCEANVIEW
$6,897
BALCONY
$7,501
SUITE
$10,214
From 6,283
View Trip
9 Day Cartagena to Lima with Silversea
Cruise

9 Days (8 Nights) Cartagena to Lima
Cruise Line: Silversea
Ship: Silver Ray
Departure: 27 December 2024
Countries Visited: Colombia, Panama, Ecuador, Peru
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,296
From 10,296
View Trip
17 Day Canary Islands Crossing with Regent Seven Seas
Cruise

17 Days (16 Nights) Rio de Janeiro to Lisbon
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 13 March 2025
Countries Visited: Brazil, Cape Verde, Spain, Portugal
Non-Use Land Package Credit
INSIDE
-
OCEANVIEW
-
BALCONY
$10,831
SUITE
$12,316
Save 5,659
From 10,831
View Trip
34 Day Hamburg To Rio De Janeiro with Cunard
Cruise

34 Days (33 Nights) Hamburg to Rio de Janeiro
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 04 January 2025
Countries Visited: Germany, Holland, Belgium, England (+5 more), Portugal, USA, Turks and Caicos Islands, Barbados, Brazil
INSIDE
$8,216
OCEANVIEW
$9,614
BALCONY
$12,584
SUITE
$28,721
From 8,216
View Trip
17 Day Colombia, Ecuador & Peru Voyage with Azamara Cruises
Cruise
 (1)

17 Days (16 Nights) Miami to Lima
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 07 January 2025
Countries Visited: USA, Aruba, Bonaire, Curacao (+3 more), Colombia, Ecuador, Peru
INSIDE
$6,626
OCEANVIEW
$7,826
BALCONY
$9,665
SUITE
$15,182
From 6,626
View Trip
25 Day Amazonian Mystique with Oceania Cruises
Cruise
 (1)

25 Days (24 Nights) Miami to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Nautica
Departure: 09 November 2024
Countries Visited: USA, Antigua and Barbuda, Saint Lucia, Grenada (+7 more), Trinidad and Tobago, Brazil, Barbados, Dominica, Virgin Islands, Puerto Rico, Bahamas
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,820
BALCONY
$16,077
SUITE
$21,264
Save 2,070
From 10,820
View Trip
Results: 31-60 of 113

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