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Cayman Islands Cruises

Are you looking for a cruise to Cayman Islands? Choose from 94 unique cruise itineraries to Cayman Islands, departing from Fort Lauderdale, Galveston, Los Angeles, Miami, New Orleans and more. February is the most popular month to cruise to Cayman Islands and we have over 296 departures available from ten of the world's leading cruise lines.
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94 Cruises (296 Cruise Departures)
10 Day Aruba, Curacao & Bonaire with Celebrity Cruises
Cruise
 (2)

10 Days (9 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departure: 05 December 2024
Countries Visited: USA, Bonaire, Aruba, Curacao (+1 more), Cayman Islands
Exclusive Offer
INSIDE
$1,592
OCEANVIEW
$1,979
BALCONY
$2,215
SUITE
$4,816
Save 2,659
From 1,592
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7 Day Western Caribbean Cruise with Royal Caribbean
Cruise
 (1)

7 Days (6 Nights) San Juan to Tampa
Cruise Line: Royal Caribbean
Ship: Rhapsody of the Seas
Departure: 02 November 2025
Countries Visited: Puerto Rico, Dominican Republic, Jamaica, Cayman Islands (+1 more), USA
Exclusive Deal
INSIDE
$1,191
OCEANVIEW
$1,327
BALCONY
$1,981
SUITE
$2,295
Save 514
From 1,085
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8 Day Western Caribbean with Holland America
Cruise
 (2)

8 Days (7 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ships: Nieuw Amsterdam, Nieuw Statendam
Departures: Dec 2024 to Dec 2024
Countries Visited: USA, Mexico, Cayman Islands, Jamaica (+1 more), Bahamas
Have It All Offer
INSIDE
$1,852
OCEANVIEW
$2,089
BALCONY
$2,466
SUITE
$3,238
From 1,852
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10 Day Aruba, Curacao & Bonaire with Celebrity Cruises
Cruise
 (2)

10 Days (9 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Eclipse
Departures: Jan 2025 to Jan 2025
Countries Visited: USA, Bonaire, Curacao, Aruba (+1 more), Cayman Islands
Exclusive Offer
INSIDE
$1,624
OCEANVIEW
$1,866
BALCONY
$2,053
SUITE
$5,241
Save 2,769
From 1,624
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8 Day Caribbean with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Orlando to Orlando
Ship: Norwegian Jade
Departures: Jun 2024 to Aug 2024
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
INSIDE
$2,288
OCEANVIEW
$2,441
BALCONY
$3,281
SUITE
$3,389
From 2,288
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8 Day Western Caribbean Holiday with Royal Caribbean
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Independence of the Seas
Departure: 21 December 2025
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
Exclusive Deal
INSIDE
$2,317
OCEANVIEW
$3,102
BALCONY
$3,517
SUITE
$4,704
Save 874
From 2,026
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8 Day Western Caribbean with Holland America
Cruise

8 Days (7 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 17 November 2024
Countries Visited: USA, Mexico, Cayman Islands, Jamaica (+1 more), Bahamas
Have It All Offer
INSIDE
$1,961
OCEANVIEW
$2,159
BALCONY
$2,466
SUITE
$3,386
From 1,961
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11 Day Western Caribbean Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ship: Jewel of the Seas
Departure: 13 January 2025
Countries Visited: USA, Mexico, Belize, Honduras (+1 more), Cayman Islands
Exclusive Deal
INSIDE
$1,507
OCEANVIEW
$1,685
BALCONY
$2,178
SUITE
$3,522
Save 1,077
From 1,507
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9 Day Caribbean And Antilles with MSC Cruises
Cruise

9 Days (8 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Seascape
Departure: 05 April 2025
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
Early Booking Offer
INSIDE
$2,127
OCEANVIEW
$2,365
BALCONY
$2,662
SUITE
$3,285
From 2,127
View Trip
8 Day Western Caribbean with Princess
Cruise

8 Days (7 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Princess
Ship: Sky Princess
Departures: Dec 2024 to Feb 2025
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
INSIDE
$1,189
OCEANVIEW
$1,723
BALCONY
$1,419
SUITE
$1,814
From 1,189
View Trip
8 Day Western Caribbean with Holland America
Cruise

8 Days (7 Nights) Fort Lauderdale to Fort Lauderdale
Cruise Line: Holland America
Ships: Eurodam, Nieuw Amsterdam (+1 more), Nieuw Statendam
Departures: Nov 2024 to Mar 2026
Countries Visited: USA, Cayman Islands, Jamaica, Turks and Caicos Islands (+1 more), Bahamas
Have It All Offer
INSIDE
$1,763
OCEANVIEW
$2,149
BALCONY
$2,376
SUITE
$2,911
From 1,763
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8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Seascape
Departure: 28 December 2024
Countries Visited: USA, Jamaica, Cayman Islands, Mexico (+1 more), Bahamas
Save And Sail Offer
INSIDE
$2,608
OCEANVIEW
$2,806
BALCONY
$3,073
SUITE
$4,039
From 2,608
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16 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

16 Days (15 Nights) Los Angeles to Fort Lauderdale
Cruise Line: Celebrity Cruises
Ship: Celebrity Summit
Departure: 19 September 2024
Countries Visited: USA, Mexico, Costa Rica, Colombia (+1 more), Cayman Islands
Exclusive Offer
INSIDE
$2,505
OCEANVIEW
$3,037
BALCONY
$6,768
SUITE
$13,236
Save 3,872
From 2,505
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8 Day Western Caribbean & Perfect Day with Royal Caribbean
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Independence of the Seas
Departure: 07 December 2025
Countries Visited: USA, Bahamas, Cayman Islands, Jamaica (+1 more), Haiti
Exclusive Deal
INSIDE
$1,692
OCEANVIEW
$2,061
BALCONY
$2,223
SUITE
$3,218
Save 636
From 1,484
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10 Day Western Caribbean Cruise with Royal Caribbean
Cruise

10 Days (9 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ship: Enchantment of the Seas
Departure: 26 October 2024
Countries Visited: USA, Cayman Islands, Jamaica, Mexico (+1 more), Honduras
Exclusive Deal
INSIDE
$1,484
OCEANVIEW
$1,580
BALCONY
$2,281
SUITE
$3,632
Save 595
From 1,365
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8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Seascape
Departures: Jan 2025 to Mar 2025
Countries Visited: USA, Jamaica, Cayman Islands, Mexico (+1 more), Bahamas
Save And Sail Offer
INSIDE
$1,212
OCEANVIEW
$1,410
BALCONY
$1,678
SUITE
$2,331
From 1,212
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13 Day Caribbean And Antilles with MSC Cruises
Cruise

13 Days (12 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Seascape
Departure: 05 April 2025
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
Early Booking Offer
INSIDE
$2,952
OCEANVIEW
$3,289
BALCONY
$3,695
SUITE
$4,675
From 2,952
View Trip
10 Day Western Caribbean Cruise with Royal Caribbean
Cruise

10 Days (9 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ship: Serenade of the Seas
Departures: Oct 2024 to Feb 2025
Countries Visited: USA, Cayman Islands, Panama, Costa Rica (+1 more), Mexico
Exclusive Deal
INSIDE
$1,474
OCEANVIEW
$1,495
BALCONY
$1,889
SUITE
$3,128
Save 1,339
From 1,474
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11 Day A Journey From Miami To Miami with Explora Journeys
Cruise

11 Days (10 Nights) Miami to Miami
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 25 January 2026
Countries Visited: USA, Jamaica, Cayman Islands, Mexico (+1 more), Bahamas
Unique EscapesPenthouse Dream Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$7,168
SUITE
$8,752
From 7,168
View Trip
8 Day Western Caribbean & Perfect Day with Royal Caribbean
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Royal Caribbean
Ship: Independence of the Seas
Departures: Nov 2025 to Apr 2026
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
Exclusive Deal
INSIDE
$1,478
OCEANVIEW
$1,833
BALCONY
$1,996
SUITE
$2,814
Save 777
From 1,325
View Trip
8 Day Western Caribbean - Port Canaveral with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Orlando to Orlando
Ship: Norwegian Epic
Departures: Nov 2024 to Mar 2025
Countries Visited: USA, Mexico, Cayman Islands, Jamaica (+1 more), Bahamas
Exclusive Solo Offer
INSIDE
$2,151
OCEANVIEW
-
BALCONY
$2,839
SUITE
$3,114
From 2,151
View Trip
11 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Tampa to Tampa
Cruise Line: Royal Caribbean
Ships: Enchantment of the Seas, Grandeur of the Seas
Departures: Apr 2025 to Apr 2025
Countries Visited: USA, Cayman Islands, Aruba, Bonaire (+1 more), Curacao
Exclusive Deal
INSIDE
$1,780
OCEANVIEW
$1,983
BALCONY
$4,307
SUITE
$4,408
Save 759
From 1,559
View Trip
8 Day Caribbean with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Orlando to Orlando
Ship: Norwegian Prima
Departures: Nov 2025 to Apr 2026
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
INSIDE
$2,157
OCEANVIEW
$2,540
BALCONY
$2,845
SUITE
$3,915
From 2,157
View Trip
8 Day Western Caribbean - Port Canaveral with Norwegian Cruise Line
Cruise

8 Days (7 Nights) Orlando to Orlando
Ships: Norwegian Epic, Norwegian Prima
Departures: Feb 2025 to Feb 2026
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
INSIDE
$1,999
OCEANVIEW
$2,563
BALCONY
$2,868
SUITE
$3,651
From 1,999
View Trip
8 Day Caribbean And Antilles with MSC Cruises
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: MSC Cruises
Ship: MSC Seascape
Departures: Jun 2024 to Dec 2024
Countries Visited: USA, Jamaica, Cayman Islands, Mexico (+1 more), Bahamas
Mutiple Deals Available
INSIDE
$1,202
OCEANVIEW
$1,410
BALCONY
$1,597
SUITE
$2,331
From 1,202
View Trip
12 Day Southern Caribbean Cruise with Royal Caribbean
Cruise

12 Days (11 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ship: Jewel of the Seas
Departure: 18 November 2024
Countries Visited: USA, Mexico, Curacao, Aruba (+1 more), Cayman Islands
Exclusive Deal
INSIDE
$1,712
OCEANVIEW
$1,910
BALCONY
$2,291
SUITE
-
Save 766
From 1,660
View Trip
11 Day Western Caribbean Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ship: Jewel of the Seas
Departures: Dec 2024 to Apr 2025
Countries Visited: USA, Mexico, Belize, Honduras (+1 more), Cayman Islands
Exclusive Deal
INSIDE
$1,585
OCEANVIEW
$1,536
BALCONY
$1,923
SUITE
$3,137
Save 1,003
From 1,536
View Trip
8 Day Western Caribbean: Greater Antilles & Mexico with Holland America
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Holland America
Ship: Zuiderdam
Departures: Nov 2025 to Jan 2026
Countries Visited: USA, Bahamas, Jamaica, Cayman Islands (+1 more), Mexico
Have It All Offer
INSIDE
$1,911
OCEANVIEW
$2,159
BALCONY
$2,505
SUITE
$3,792
From 1,911
View Trip
11 Day Western Caribbean Cruise with Royal Caribbean
Cruise

11 Days (10 Nights) Galveston to Galveston
Cruise Line: Royal Caribbean
Ship: Jewel of the Seas
Departure: 08 November 2024
Countries Visited: USA, Mexico, Belize, Honduras (+1 more), Cayman Islands
Exclusive Deal
INSIDE
$1,680
OCEANVIEW
$1,745
BALCONY
$1,922
SUITE
-
Save 615
From 1,393
View Trip
8 Day Cayman, Bahamas, Mexico & Jamaica with Celebrity Cruises
Cruise

8 Days (7 Nights) Miami to Miami
Cruise Line: Celebrity Cruises
Ship: Celebrity Beyond
Departures: May 2025 to Aug 2025
Countries Visited: USA, Bahamas, Mexico, Cayman Islands (+1 more), Jamaica
Exclusive Offer
INSIDE
$1,479
OCEANVIEW
$1,557
BALCONY
$1,761
SUITE
$6,206
Save 2,524
From 1,479
View Trip
Results: 61-90 of 94

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