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South America Tours Starting In October 2025

If you're looking at joining a tour through South America in October 2025, we have 165 unique tours and small group adventures with 11,310 departures from the world's leading tour operators departing in October.
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Departures (October 2025)
< September 2025 November 2025 >
Duration
3 Days
65 Days
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Price
$500pp
$75,685pp
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165 Tours (11,310 Tour Departures)
19 Day Ultimate South America with Cosmos
Tour
 (13)

19 Days Rio de Janeiro to Lima
Operated By: Cosmos
Departures: Oct 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Peru
Exclusive Savings
From 7,789
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20 Day Brazil, Argentina & Chile Unveiled with Peru with Cosmos
Tour
 (2)

20 Days Rio de Janeiro to Lima
Operated By: Cosmos
Departures: Jul 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
From 8,081
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22 Day South American Odyssey with Peru with Globus
Tour
 (3)

22 Days Rio de Janeiro to Lima
Operated By: Globus
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
Save 242
From 13,417
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23 Day Ultimate South America with Brazil's Amazon with Cosmos
Tour
 (3)

23 Days Manaus to Lima
Operated By: Cosmos
Departures: Nov 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Peru
Exclusive Savings
From 9,973
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30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Oct 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From 16,620
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8 Day Highlights of Peru with Trafalgar
Tour
 (2)

8 Days Lima to Lima
Operated By: Trafalgar
Departures: Jun 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Deal
Save 760
From 4,706
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8 Day Peru Splendours with Globus
Tour
 (2)

8 Days Lima to Lima
Operated By: Globus
Departures: Jun 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Savings
Save 89
From 4,716
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26 Day South American Odyssey with Brazil's Amazon & Peru with Globus
Tour
 (2)

26 Days Manaus to Lima
Operated By: Globus
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
Save 282
From 15,790
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21 Day Absolute Peru (Inca Trail) with G Adventures
Tour
 (1)

21 Days Lima to Lima
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group, Walking & Hiking, Inca Trail
Countries Visited: Peru
Exclusive Deal
Save 2,047
From 4,622
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14 Day Adventures in Patagonia with Explore!
Tour
 (1)

14 Days Buenos Aires to Buenos Aires
Operated By: Explore!
Departures: Oct 2024 to Dec 2025
Trip Styles: Adventure, Group
Countries Visited: Chile, Argentina
Exclusive Savings
Save 195
From 9,202
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17 Day Adventures in Patagonia with Iguazu Extension with Explore!
Tour
 (1)

17 Days Buenos Aires to Buenos Aires
Operated By: Explore!
Departures: Oct 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Chile, Argentina
Exclusive Savings
Save 220
From 10,496
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18 Day Andes, Iguassu & Beyond with G Adventures
Tour
 (1)

18 Days Santiago to Rio de Janeiro
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Chile, Brazil
Exclusive Deal
Save 1,358
From 4,434
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24 Day Brazil, Argentina & Chile Unveiled with Peru and Brazil's Amazon with Cosmos
Tour
 (1)

24 Days Manaus to Lima
Operated By: Cosmos
Departures: Jul 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile, Peru
Exclusive Savings
From 10,239
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14 Day Discover Patagonia with G Adventures
Tour
 (1)

14 Days Buenos Aires to Buenos Aires
Operated By: G Adventures
Departures: Oct 2024 to Mar 2025
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Chile
Exclusive Savings
Save 205
From 8,329
View Trip
9 Day Ecuador: Amazon, Hot Springs & Volcanoes with G Adventures
Tour
 (1)

9 Days Quito to Quito
Operated By: G Adventures
Departures: Apr 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Ecuador
Exclusive Deal
Save 746
From 2,153
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9 Day Galápagos Island Hopping with Quito with G Adventures
Tour
 (1)

9 Days Quito to Quito
Operated By: G Adventures
Departures: Apr 2024 to Dec 2025
Trip Styles: Adventure, Group, Island Hopping, Wildlife
Countries Visited: Ecuador, Galapagos
Exclusive Deal
Save 1,332
From 3,007
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23 Day Grand South America with Luxury Gold
Tour
 (1)

23 Days Lima to Rio de Janeiro
Operated By: Luxury Gold
Departures: Aug 2024 to Nov 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru, Chile, Argentina, Brazil
Founder's Collection
Save 494
From 27,432
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9 Day Iguassu & Beyond with G Adventures
Tour
 (1)

9 Days Buenos Aires to Rio de Janeiro
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Brazil
Exclusive Savings
Save 76
From 3,135
View Trip
11 Day In the Footsteps of the Incas with Trafalgar
Tour
 (1)

11 Days Lima to Lima
Operated By: Trafalgar
Departures: May 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Peru
Exclusive Deal
Save 774
From 8,007
View Trip
12 Day South American Getaway with Santiago with Globus
Tour
 (1)

12 Days Rio de Janeiro to Santiago
Operated By: Globus
Departures: Jul 2024 to Dec 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile
Exclusive Savings
Save 125
From 6,826
View Trip
23 Day South American Odyssey with Brazil Amazon & Easter Island with Globus
Tour
 (1)

23 Days Manaus to Santiago
Operated By: Globus
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Easter Island, Chile
Exclusive Savings
Save 258
From 15,268
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6 Day Torres del Paine - The W Trek with G Adventures
Tour
 (1)

6 Days Puerto Natales to Puerto Natales
Operated By: G Adventures
Departures: Oct 2024 to Apr 2025
Trip Styles: Adventure, Small Group, Short Break, Walking & Hiking
Countries Visited: Chile
Exclusive Savings
Save 86
From 2,743
View Trip
26 Day Ultimate South America with a Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Oct 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
From 14,462
View Trip
11 Day Wild Peru with Crooked Compass
New ReleaseTour
 (1)

11 Days Cusco to Cusco
Operated By: Crooked Compass
Departures: Apr 2024 to Oct 2025
Trip Styles: Adventure, Small Group, Walking & Hiking, Cultural, Off The Beaten Track
Countries Visited: Peru
From 8,060
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12 Day Essence of South America with Tauck
Tour

12 Days Río de Janeiro to Santiago
Operated By: Tauck
Departures: Sep 2024 to Oct 2025
Trip Styles: Coach, Group, Scenic
Countries Visited: Brazil, Argentina, Chile
From 17,260
View Trip
10 Day Machu Picchu and the Amazon (Inca Trail) with G Adventures
Tour

10 Days Lima to Cusco
Operated By: G Adventures
Departures: Apr 2024 to Dec 2025
Trip Styles: Adventure, Small Group, Walking & Hiking, Inca Trail
Countries Visited: Peru
Exclusive Deal
Save 1,122
From 3,237
View Trip
18 Day The Explorer with Contiki
Tour

18 Days Cusco to Rio de Janeiro
Operated By: Contiki
Departures: May 2024 to Feb 2026
Trip Styles: Coach, Group, 18-30's, Scenic
Countries Visited: Peru, Argentina, Brazil
Exclusive Savings
Save 779
From 9,366
View Trip
10 Day Highlights of Chile & Argentina with G Adventures
Tour

10 Days Santiago to Buenos Aires
Operated By: G Adventures
Departures: Apr 2024 to Jan 2026
Trip Styles: Adventure, Small Group
Countries Visited: Argentina, Chile
Exclusive Savings
Save 73
From 2,939
View Trip
31 Day Bolivia to Brazil: Highlands & Coastlines with G Adventures
Tour

31 Days La Paz to Rio de Janeiro
Operated By: G Adventures
Departures: May 2024 to Dec 2025
Trip Styles: Adventure, Small Group, 18-30's
Countries Visited: Argentina, Brazil, Chile, Bolivia (+1 more), Uruguay
Exclusive Deal
Save 1,497
From 5,702
View Trip
14 Day Simply Peru with Explore!
Tour

14 Days Lima to Cusco
Operated By: Explore!
Departures: May 2024 to Oct 2025
Trip Styles: Adventure, Small Group
Countries Visited: Peru
Exclusive Savings
Save 70
From 3,401
View Trip
Results: 1-30 of 165

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