Home > All River Cruises > Asia River Cruises > Mekong River Cruises > Cambodia > September 2025

Cambodia River Cruises Starting In September 2025

If you're looking at joining a river cruise through Cambodia in September 2025, we have 29 unique river cruise itineraries and 490 departures available, operated by six of the world's leading river cruise lines departing in September.
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Departures (September 2025)
< August 2025 October 2025 >
Duration
8 Days
24 Days
Countries Visited
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Price
$2,700pp
$34,280pp
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29 River Cruises (490 River Cruise Departures)
8 Day Mekong Discovery with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive DealEarlybird Offer
Save 2,852
From 4,494
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8 Day Mekong Discovery with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive DealEarlybird Offer
Save 2,849
From 4,494
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15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Ships: Mekong Jewel
Departures: Sep 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Earlybird SavingExclusive Deal
Save 1,613
From 10,783
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16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay with Avalon River Cruises
River Cruise
 (1)

16 Days Hanoi to Siem Reap
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive DealEarlybird Offer
Save 2,886
From 8,694
View Trip
15 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Siem Reap to Ho Chi Minh City
Operated By: Emerald Cruises
Ships: Emerald Harmony
Departures: Jul 2024 to Sep 2025
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
INSIDE
-
RIVER VIEW
$4,945
BALCONY
$5,732
SUITE
$7,613
Save 2,060
From 6,855
View Trip
10 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

10 Days Ho Chi Minh City to Phnom Penh
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Aug 2024 to Sep 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
$4,495
BALCONY
$5,480
SUITE
$7,580
Save 555
From 4,495
View Trip
23 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

23 Days Hanoi to Siem Reap
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Jul 2024 to Sep 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
$7,618
BALCONY
$8,603
SUITE
$10,880
Save 2,087
From 7,618
View Trip
10 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

10 Days Phnom Penh to Ho Chi Minh City
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Aug 2024 to Oct 2025
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
INSIDE
-
RIVER VIEW
$4,495
BALCONY
$5,282
SUITE
$7,163
Save 555
From 4,495
View Trip
23 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

23 Days Hanoi to Ho Chi Minh City
Operated By: Emerald Cruises
Ship: Emerald Harmony
Departures: Aug 2024 to Sep 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
$8,212
BALCONY
$8,999
SUITE
$12,730
Save 2,083
From 8,212
View Trip
15 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Ho Chi Minh City to Siem Reap
Operated By: Emerald Cruises
Ships: Emerald Harmony
Departures: Aug 2024 to Sep 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
$4,945
BALCONY
$5,930
SUITE
$8,207
Save 2,060
From 6,855
View Trip
19 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

19 Days Hanoi to Ho Chi Minh City
Operated By: Emerald Cruises
Ships: Emerald Harmony
Departures: Jul 2024 to Sep 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
$6,777
BALCONY
$7,564
SUITE
$9,445
Save 2,078
From 8,668
View Trip
13 Day Temple Discovery and Meandering along the Mekong Cruise with Scenic
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Operated By: Scenic
Ship: Scenic Spirit
Departures: Jul 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$7,049
SUITE
$9,717
Save 3,502
From 7,049
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay with Avalon River Cruises
River Cruise

16 Days Hanoi to Ho Chi Minh City
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive DealEarlybird Offer
Save 2,889
From 8,742
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15 Day Magnificent Mekong with Viking River Cruises
River Cruise

15 Days Ho Chi Minh City to Hanoi
Operated By: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Aug 2024 to Dec 2026
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Discover More Sale
INSIDE
-
RIVER VIEW
-
BALCONY
$7,519
SUITE
$18,310
Save 1,657
From 7,519
View Trip
24 Day Essence of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise

24 Days Hanoi to Ho Chi Minh City
Operated By: Scenic
Ship: Scenic Spirit
Departures: Aug 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$13,058
SUITE
$15,726
Save 4,446
From 13,058
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise

15 Days Hanoi to Ho Chi Minh City
Operated By: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Aug 2024 to Dec 2026
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Discover More Sale
INSIDE
-
RIVER VIEW
-
BALCONY
$7,123
SUITE
$17,617
Save 1,545
From 7,123
View Trip
20 Day Highlights of Vietnam, Cambodia & Luxury Mekong with Scenic
River Cruise

20 Days Hanoi to Siem Reap
Operated By: Scenic
Ship: Scenic Spirit
Departures: Jul 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$11,331
SUITE
$13,999
Save 4,445
From 11,331
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Ho Chi Minh City to Siem Reap
Operated By: Scenic
Ship: Scenic Spirit
Departures: Jul 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$7,123
SUITE
$9,791
Save 4,403
From 7,123
View Trip
13 Day Meandering along the Mekong and Temple Discovery Cruise with Scenic
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Operated By: Scenic
Ship: Scenic Spirit
Departures: Jul 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$7,049
SUITE
$9,717
Save 3,502
From 7,049
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River with Avalon River Cruises
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive DealEarlybird Offer
Save 2,873
From 6,753
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise

15 Days Ho Chi Minh City to Hanoi
Ships: Mekong Jewel
Departures: Sep 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Earlybird SavingExclusive Deal
Save 1,596
From 10,783
View Trip
20 Day Highlights of Cambodia, Vietnam & Luxury Mekong with Scenic
River Cruise

20 Days Hanoi to Ho Chi Minh City
Operated By: Scenic
Ship: Scenic Spirit
Departures: Jul 2025 to Sep 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$11,331
SUITE
$13,999
Save 4,428
From 11,331
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River with Avalon River Cruises
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia
Exclusive DealEarlybird Offer
Save 2,871
From 6,842
View Trip
15 Day Treasures of the Mekong Meandering Cruise with Scenic
River Cruise

15 Days Siem Reap to Ho Chi Minh City
Operated By: Scenic
Ship: Scenic Spirit
Departures: Jul 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Cambodia, Vietnam
Exclusive Deal
INSIDE
-
RIVER VIEW
-
BALCONY
$7,123
SUITE
$9,791
Save 4,403
From 7,123
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Bangkok with Avalon River Cruises
River Cruise

16 Days Siem Reap to Bangkok
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Dec 2025
Rivers: Mekong
Countries Visited: Cambodia, Vietnam, Thailand
Exclusive DealEarlybird Offer
Save 2,884
From 8,260
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Bangkok with Avalon River Cruises
River Cruise

16 Days Ho Chi Minh City to Bangkok
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia, Thailand
Exclusive DealEarlybird Offer
Save 2,882
From 8,356
View Trip
19 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi, Ha Long Bay & Bangkok with Avalon River Cruises
River Cruise

19 Days Hanoi to Bangkok
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia, Thailand
Exclusive DealEarlybird Offer
Save 2,899
From 10,197
View Trip
13 or 12 Day Cruising the Mekong: Siam, Saigon & Angkor Wat with Abercrombie & Kent
New ReleaseRiver Cruise

13 or 12 Days Bangkok to Ho Chi Minh City
Operated By: Abercrombie & Kent
Departures: Dec 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Thailand, Cambodia, Vietnam
Exclusive Solo Offer
From 16,745
View Trip
19 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi, Ha Long Bay & Bangkok with Avalon River Cruises
River Cruise

19 Days Hanoi to Bangkok
Operated By: Avalon River Cruises
Ship: Avalon Saigon
Departures: Aug 2024 to Nov 2025
Rivers: Mekong
Countries Visited: Vietnam, Cambodia, Thailand
Exclusive DealEarlybird Offer
Save 2,897
From 10,163
View Trip
Results: 29 results

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Asia River Cruises

Asia River Cruises India (Ganges) River Cruises Mekong River Cruises Yangtze River Cruises

Trip Lengths

3 Week

Departure Months

April 2024 May 2024 July 2024 August 2024 September 2024 October 2024 November 2024 December 2024 January 2025 February 2025 March 2025 April 2025 May 2025 July 2025 August 2025 September 2025 October 2025 November 2025 December 2025 January 2026 February 2026 March 2026 April 2026 August 2026 September 2026 October 2026 November 2026 December 2026

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City

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