Home > All River Cruises > Asia River Cruises > Mekong River Cruises > Cambodia > September 2026

Cambodia River Cruises Starting In September 2026

If you're looking at joining a river cruise through Cambodia in September 2026, we have 26 unique river cruise itineraries and 586 departures available, operated by five of the world's leading river cruise lines departing in September.
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Departures (September 2026)
< August 2026 October 2026 >
Duration
8 Days
23 Days
Countries Visited
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Operators
Price
$1,700pp
$22,099pp
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26 River Cruises (586 River Cruise Departures)
8 Day Mekong Discovery (Northbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Avalon River Cruises
Ships: Avalon Saigon
Departures: Nov 2025 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
8 Day Mekong Discovery (Southbound) with Avalon River Cruises
River Cruise
 (2)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ships: Avalon Saigon
Departures: Dec 2025 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$3,177
From
US$3,177
Save 2,172
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise
 (2)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Uniworld River Cruises
Ship: Mekong Jewel
Departures: Jan 2026 to Dec 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,057
From
US$6,057
Save 2,250
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Northbound) with Avalon River Cruises
River Cruise
 (1)

16 Days Hanoi to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Jan 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,530
From
US$6,530
Save 2,293
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Nov 2025 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,499
Suite
$11,999
From
US$6,499
Save 2,000
Per Person
View Trip
15 Day Magnificent Mekong with Viking River Cruises
River Cruise
 (1)

15 Days Hanoi to Ho Chi Minh City
Cruise Line: Viking River Cruises
Ships: Viking Saigon, Viking Tonle
Departures: Nov 2025 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Multiple Deals Available
Inside
-
River View
-
Balcony
$6,499
Suite
$11,999
From
US$6,499
Save 2,500
Per Person
View Trip
13 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (4)

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Nov 2025 to May 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Payment Discount
Fly Free Economy
Exclusive Savings
Inside
-
River View
$5,203
Balcony
$5,688
Suite
$8,307
From
US$5,203
Save 6,456
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

10 Days Ho Chi Minh City to Phnom Penh
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Aug 2026 to Sep 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
$8,537
Balcony
$9,507
Suite
$13,969
From
US$8,537
Save 277
Per Person
View Trip
8 Day Charms of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Ho Chi Minh City to Siem Reap
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Mar 2026 to Dec 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
$1,767
Suite
$3,686
From
US$2,888
Save 1,328
Per Person
View Trip
15 Day Timeless Wonders of Vietnam, Cambodia & the Mekong with Uniworld River Cruises
River Cruise

15 Days Ho Chi Minh City to Hanoi
Cruise Line: Uniworld River Cruises
Ship: Mekong Jewel
Departures: Jan 2026 to Dec 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,313
From
US$5,313
Save 2,262
Per Person
View Trip
19 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

19 Days Hanoi to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Aug 2026 to Sep 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
$11,160
Balcony
$12,130
Suite
$16,592
From
US$11,160
Save 325
Per Person
View Trip
8 Day Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

8 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Nov 2025 to May 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Early Payment Discount
Fly Free Economy
Exclusive Savings
Inside
-
River View
$3,884
Balcony
$4,369
Suite
$6,988
From
US$3,884
Save 6,415
Per Person
View Trip
15 Day Wonders of Vietnam, Cambodia & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Ho Chi Minh City to Siem Reap
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Aug 2026 to Dec 2026
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Exclusive Savings
Inside
-
River View
$9,856
Balcony
$6,684
Suite
$15,288
From
US$6,684
Save 5,666
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Southbound) with Avalon River Cruises
River Cruise

16 Days Hanoi to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ships: Avalon Saigon
Departures: Nov 2025 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,593
From
US$6,593
Save 2,290
Per Person
View Trip
21 Day Grand Tour of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

21 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Jan 2026 to Apr 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Exclusive Savings
Inside
-
River View
$7,510
Balcony
$7,995
Suite
$10,226
From
US$7,510
Save 5,635
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Southbound) with Avalon River Cruises
River Cruise

13 Days Siem Reap to Ho Chi Minh City
Cruise Line: Avalon River Cruises
Ships: Avalon Saigon
Departures: Dec 2025 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,032
From
US$5,032
Save 2,242
Per Person
View Trip
8 Day Riches of the Mekong with AmaWaterways
New ReleaseRiver Cruise

8 Days Siem Reap to Ho Chi Minh City
Cruise Line: AmaWaterways
Ships: AmaDara, AmaMaya
Departures: Jan 2026 to Dec 2027
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
-
Balcony
$1,959
Suite
$3,848
From
US$2,888
Save 1,328
Per Person
View Trip
17 Day Treasures & Temples of Vietnam & Cambodia with Emerald Cruises
River Cruise
 (4)

17 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Dec 2025 to May 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Fly Free Economy
Early Payment Discount
Exclusive Savings
Inside
-
River View
$6,508
Balcony
$6,993
Suite
$9,612
From
US$6,896
Save 6,177
Per Person
View Trip
15 Day Wonders of Cambodia, Vietnam & the Mekong with Emerald Cruises
River Cruise
 (4)

15 Days Siem Reap to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Jul 2026 to Dec 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Fly Free Economy
Exclusive Savings
Inside
-
River View
$6,199
Balcony
$6,684
Suite
$15,288
From
US$6,199
Save 5,151
Per Person
View Trip
10 Day Meandering Majestic Mekong Cruise with Emerald Cruises
River Cruise
 (4)

10 Days Phnom Penh to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ship: Emerald Harmony
Departures: Sep 2026 to Dec 2026
Rivers: Mekong
Visit: Cambodia, Vietnam
Exclusive Savings
Inside
-
River View
$9,313
Balcony
$10,283
Suite
-
From
US$9,313
Save 289
Per Person
View Trip
13 Day Fascinating Vietnam, Cambodia & the Mekong River (Northbound) with Avalon River Cruises
River Cruise

13 Days Ho Chi Minh City to Siem Reap
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Jan 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$5,099
From
US$5,099
Save 2,244
Per Person
View Trip
23 Day Indochina Mekong Journey with Emerald Cruises
River Cruise
 (4)

23 Days Hanoi to Ho Chi Minh City
Cruise Line: Emerald Cruises
Ships: Emerald Harmony
Departures: Mar 2026 to Apr 2027
Rivers: Mekong
Visit: Vietnam, Laos, Cambodia
Fly Free Economy
Exclusive Savings
Inside
-
River View
$8,550
Balcony
$9,035
Suite
$11,266
From
US$8,550
Save 5,680
Per Person
View Trip
19 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi, Ha Long Bay & Bangkok (Northbound) with Avalon River Cruises
River Cruise

19 Days Hanoi to Bangkok
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Jan 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Thailand
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$7,746
From
US$7,746
Save 2,327
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Southbound) with Avalon River Cruises
River Cruise

16 Days Siem Reap to Bangkok
Cruise Line: Avalon River Cruises
Ships: Avalon Saigon
Departures: Dec 2025 to Nov 2027
Rivers: Mekong
Visit: Cambodia, Vietnam, Thailand
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,276
From
US$6,276
Save 2,277
Per Person
View Trip
19 Day Fascinating Vietnam, Cambodia & the Mekong River with Hanoi, Ha Long Bay & Bangkok (Southbound) with Avalon River Cruises
River Cruise

19 Days Hanoi to Bangkok
Cruise Line: Avalon River Cruises
Ships: Avalon Saigon
Departures: Nov 2025 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Thailand
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$7,794
From
US$7,794
Save 2,324
Per Person
View Trip
16 Day Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Northbound) with Avalon River Cruises
River Cruise

16 Days Ho Chi Minh City to Bangkok
Cruise Line: Avalon River Cruises
Ship: Avalon Saigon
Departures: Jan 2026 to Nov 2027
Rivers: Mekong
Visit: Vietnam, Cambodia, Thailand
Exclusive Savings
Inside
-
River View
-
Balcony
-
Suite
$6,363
From
US$6,363
Save 2,280
Per Person
View Trip
Results: 26 results

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Asia River Cruises

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Trip Lengths

10 Day

Departure Months

November 2025 December 2025 January 2026 February 2026 March 2026 April 2026 May 2026 July 2026 August 2026 September 2026 October 2026 November 2026 December 2026 January 2027 February 2027 March 2027 April 2027 May 2027 July 2027 August 2027 September 2027 October 2027 November 2027 December 2027

Cities

Siem Reap

Routes

Hanoi to Siem Reap Ho Chi Minh City to Siem Reap Siem Reap to Ho Chi Minh City

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