All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 1,876 expeditions and cruises around South America travelling with the world's leading cruise lines.
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2 Days
87 Days
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349 Cruises (1,876 Cruise Departures)
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save 242
From 15,892
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Apr 2024 to Dec 2025
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 3,092
From 7,158
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2024 to Dec 2024
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,977
From 4,642
Tour + Cruise
 (1)

26 Days Manaus to Guayaquil
Operated By: Globus
Departures: Sep 2024 to Nov 2024
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save 295
From 18,726
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Jun 2024 to Dec 2025
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 215
From 10,045
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Sep 2024 to Nov 2025
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Exclusive Savings
Save 211
From 13,877
Cruise
 (1)

20 Days (19 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 11 March 2025
Countries Visited: Argentina, Falkland Islands, South Georgia Island
Exclusive Savings
INSIDE
-
OCEANVIEW
$17,393
BALCONY
$19,402
SUITE
$28,614
Save 327
From 17,393
Cruise
 (3)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Departures: Nov 2024 to Feb 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,400
SUITE
$18,805
Save 1,120
From 9,400
Cruise
 (1)

32 Days (31 Nights) Buenos Aires to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2025 to Mar 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile (+5 more), Peru, Ecuador, Panama, Cayman Islands, USA
Have It All Offer
INSIDE
$8,463
OCEANVIEW
$8,731
BALCONY
$10,909
SUITE
$14,453
From 8,463
Cruise
 (1)

18 Days (17 Nights) Fort Lauderdale to San Antonio
Cruise Line: Holland America
Ship: Oosterdam
Departures: Nov 2024 to Nov 2025
Countries Visited: USA, Cayman Islands, Panama, Ecuador (+2 more), Peru, Chile
Have It All Offer
INSIDE
$4,401
OCEANVIEW
$4,539
BALCONY
$5,460
SUITE
$7,262
From 4,401
Cruise
 (1)

18 Days (17 Nights) San Antonio to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2025 to Mar 2026
Countries Visited: Chile, Peru, Ecuador, Panama (+2 more), Cayman Islands, USA
Have It All Offer
INSIDE
$4,749
OCEANVIEW
$4,887
BALCONY
$5,996
SUITE
$8,491
From 4,749
Cruise
 (1)

15 Days (14 Nights) Buenos Aires to San Antonio
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2025 to Mar 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Have It All Offer
INSIDE
$4,022
OCEANVIEW
$4,160
BALCONY
$5,338
SUITE
$6,586
From 4,022
Cruise
 (3)

18 Days (17 Nights) Buenos Aires to Santiago
Cruise Line: Viking Cruises
Departures: Nov 2024 to Feb 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,400
SUITE
$18,805
Save 1,122
From 9,400
Cruise
 (2)

8 Days (7 Nights) Buenos Aires to Rio de Janeiro
Cruise Line: Celebrity Cruises
Departure: 20 April 2024
Countries Visited: Argentina, Uruguay, Brazil
Exclusive Deal
INSIDE
$1,551
OCEANVIEW
$1,719
BALCONY
$2,147
SUITE
$6,290
Save 1,562
From 1,551
Cruise
 (1)

15 Days (14 Nights) San Antonio to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Dec 2024 to Feb 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Have It All Offer
INSIDE
$3,664
OCEANVIEW
$3,803
BALCONY
$4,843
SUITE
$6,229
From 3,664
Cruise
 (1)

10 Days (9 Nights) Hanga Roa to Ushuaia
Cruise Line: Ponant
Ship: Le Boreal
Departure: 05 November 2024
Countries Visited: Easter Island, Argentina
Exclusive Savings
INSIDE
-
OCEANVIEW
$3,296
BALCONY
$3,551
SUITE
$5,315
Save 54
From 3,296
Cruise
 (1)

32 Days (31 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Nov 2024 to Nov 2025
Countries Visited: USA, Cayman Islands, Panama, Ecuador (+5 more), Peru, Chile, Argentina, Falkland Islands, Uruguay
Have It All Offer
INSIDE
$7,788
OCEANVIEW
$8,055
BALCONY
$9,927
SUITE
$12,946
From 7,788
Cruise
 (3)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Departure: 19 December 2024
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
INSIDE
$3,922
OCEANVIEW
-
BALCONY
$4,774
SUITE
$6,337
From 3,922
Cruise

9 Days (8 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Departures: Dec 2024 to Jan 2025
Countries Visited: Brazil, Argentina, Uruguay
Early Booking Offer
INSIDE
$1,447
OCEANVIEW
$1,606
BALCONY
$1,903
SUITE
$3,348
From 1,447
Cruise

6 Days (5 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Departure: 09 December 2024
Countries Visited: Brazil
Early Booking Offer
INSIDE
$1,007
OCEANVIEW
$1,116
BALCONY
$1,304
SUITE
$2,165
From 1,007
Cruise

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Apr 2024 to Dec 2024
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,022
From 5,597
Cruise

13 Days (12 Nights) Valparaiso to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 09 February 2025
Countries Visited: Argentina, Chile
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$13,117
From 13,117
Cruise

9 Days (8 Nights) Quito to Quito
Operated By: Explore!
Departures: May 2024 to Dec 2024
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save 249
From 12,191
Cruise

9 Days (8 Nights) Guayaquil to Guayaquil
Operated By: Tauck
Departures: Jul 2024 to Dec 2025
Countries Visited: Ecuador, Galapagos
From 12,880
Cruise

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: May 2024 to Dec 2024
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 3,113
From 7,206
Cruise

8 Days (7 Nights) Lima to Panama City
Cruise Line: Silversea
Ship: Silver Ray
Departure: 04 January 2025
Countries Visited: Ecuador, Panama, Peru
Port-to-PortExclusive Solo Offer
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$4,504
From 4,504
Cruise

13 Days (12 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Departures: Nov 2024 to Oct 2025
Countries Visited: Chile, Argentina
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$13,855
SUITE
$19,795
Save 1,140
From 13,855
Cruise

6 Days (5 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Apr 2024 to Dec 2025
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save 1,546
From 3,669
Cruise

21 Days (20 Nights) Lima to Buenos Aires
Cruise Line: Silversea
Ship: Silver Ray
Departure: 01 February 2025
Countries Visited: Argentina, Chile, Peru
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$25,344
From 25,344
Cruise

17 Days (16 Nights) Fort Lauderdale to Lima
Cruise Line: Silversea
Ship: Silver Ray
Departure: 19 December 2024
Countries Visited: Aruba, Colombia, Ecuador, Netherlands Antilles (+3 more), Panama, Peru, USA
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,692
From 10,692
Results: 1-30 of 349

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Routes

Cruises from Barcelona to Fort Lauderdale Cruises from Barcelona to Athens Cruises from Barcelona to Lisbon Cruises from Barcelona to London Cruises from Barcelona to Rome Cruises from Barcelona to Venice Cruises from Barcelona to Barcelona Cruises from Barcelona to Miami Cruises from Bridgetown to Miami Cruises from Bridgetown to Bridgetown Cruises from Buenos Aires to San Antonio Cruises from Buenos Aires to Rio de Janeiro Cruises from Buenos Aires to Buenos Aires Cruises from Dover to Dover Cruises from Fort Lauderdale to Los Angeles Cruises from Fort Lauderdale to London Cruises from Fort Lauderdale to Barcelona Cruises from Fort Lauderdale to Fort Lauderdale Cruises from Fort Lauderdale to San Diego Cruises from Genoa to Genoa Cruises from Hamburg to London Cruises from Hamburg to Hamburg Cruises from Lima to Buenos Aires Cruises from Lima to Quito Cruises from Lisbon to Lisbon Cruises from Lisbon to Miami Cruises from Lisbon to Barcelona Cruises from Lisbon to Rome Cruises from London to Hamburg Cruises from London to Barcelona Cruises from London to Fort Lauderdale Cruises from London to Copenhagen Cruises from London to Rome Cruises from London to London Cruises from London to Lisbon Cruises from London to New York Cruises from Los Angeles to Miami Cruises from Los Angeles to Fort Lauderdale Cruises from Los Angeles to Los Angeles Cruises from Malaga to Malaga Cruises from Marseille to Marseille Cruises from Miami to Lisbon Cruises from Miami to Los Angeles Cruises from Miami to Rome Cruises from Miami to Panama City Cruises from Miami to Barcelona Cruises from Miami to Miami Cruises from Miami to London Cruises from Montreal to New York Cruises from New York to New York Cruises from New York to London Cruises from Papeete to Papeete Cruises from Puerto Williams to Puerto Williams Cruises from Quito to Guayaquil Cruises from Quito to Quito Cruises from Rio de Janeiro to Rio de Janeiro Cruises from Rio de Janeiro to Barcelona Cruises from Rome to London Cruises from Rome to Lisbon Cruises from Rome to Miami Cruises from Rome to Athens Cruises from Rome to Barcelona Cruises from Rome to Venice Cruises from Rome to Fort Lauderdale Cruises from Rome to Rome Cruises from San Antonio to Buenos Aires Cruises from San Juan to San Juan Cruises from Santiago to Santiago Cruises from Sao Paulo to Sao Paulo

Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from France to Brazil Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from French Polynesia to USA Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Greece Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Greece Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from England to Portugal Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain