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Cruises from San Diego

Choose from 45 unique cruise itineraries starting in San Diego, and travelling to Auckland, Calgary, Fort Lauderdale, Panama City, Punta Arenas and more. January is the most popular month to join a cruise from San Diego and you can select from 68 departures available from seven leading cruise lines.
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45 Cruises (68 Cruise Departures)
15 Day Panama Canal with Holland America
Cruise

15 Days (14 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Zaandam
Departures: Jan 2023 to Feb 2023
Countries Visited: USA, Mexico, Guatemala, Colombia (+1 more), Bahamas
Have It All Offer
Inside
$4,099
Oceanview
$4,509
Balcony
$6,849
Suite
$10,359
From 4,099
View Trip
17 Day Panama Canal Eastbound Cruise with Royal Caribbean
Cruise

17 Days (16 Nights) San Diego to Tampa
Cruise Line: Royal Caribbean
Ship: Radiance of the Seas
Departure: 07 October 2023
Countries Visited: USA, Mexico, Nicaragua, Costa Rica (+1 more), Colombia
Primed for Adventure Sale
Inside
$2,499
Oceanview
$2,699
Balcony
-
Suite
-
From 2,499
View Trip
14 Day Baja and Costa Rica Discovery with Scenic
Cruise

14 Days (13 Nights) San Diego to San Jose
Cruise Line: Scenic
Ship: Scenic Eclipse I
Departure: 28 September 2022
Countries Visited: USA, Mexico, Guatemala, El Salvador (+2 more), Nicaragua, Costa Rica
Earlybird Saving
Inside
-
Oceanview
-
Balcony
$16,515
Suite
$25,006
Save 338
From 16,557
View Trip
18 Day Circle Hawaii with Holland America
Cruise

18 Days (17 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 14 January 2023
Countries Visited: USA, Mexico
Have It All Offer
Inside
$3,599
Oceanview
$4,249
Balcony
$4,749
Suite
$6,699
From 3,599
View Trip
6 Day West Coast Getaway with San Francisco with Princess
Cruise

6 Days (5 Nights) San Diego to San Diego
Cruise Line: Princess
Ship: Diamond Princess
Departure: 01 September 2022
Countries Visited: USA, Mexico
Twice As Nice
Inside
$672
Oceanview
$713
Balcony
$942
Suite
$1,072
From 672
View Trip
52 Day Tales Of The South Pacific with Holland America
Cruise

52 Days (51 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Volendam
Departure: 02 October 2023
Countries Visited: USA, Kiribati, Samoa, Fiji (+4 more), Tonga, Niue, Cook Islands, French Polynesia
Have It All Offer
Inside
$13,450
Oceanview
$14,250
Balcony
$26,700
Suite
$44,050
From 13,450
View Trip
36 Day Hawaii, Tahiti & Marquesas with Holland America
Cruise

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 17 February 2024
Countries Visited: USA, Kiribati, French Polynesia
Have It All Offer
Inside
$9,000
Oceanview
$10,300
Balcony
$11,400
Suite
$12,300
From 9,000
View Trip
17 Day Hawaiian Islands with Princess
Cruise

17 Days (16 Nights) San Diego to San Diego
Cruise Line: Princess
Ship: Diamond Princess
Departure: 23 October 2022
Countries Visited: USA, Mexico
Twice As Nice
Inside
$1,599
Oceanview
$1,720
Balcony
$3,189
Suite
$4,009
From 1,599
View Trip
9 Day Pacific Coastal with Norwegian Cruise Line
Cruise

9 Days (8 Nights) San Diego to Vancouver
Ship: Norwegian Jewel
Departure: 23 April 2023
Countries Visited: USA, Canada
Take All 5 Free Offers + Save up to 35% + Double Your Money with CruiseFirst
Inside
$1,542
Oceanview
$1,783
Balcony
$2,435
Suite
$2,789
From 1,542
View Trip
17 Day Hawaiian Islands with Princess
Cruise

17 Days (16 Nights) San Diego to San Diego
Cruise Line: Princess
Ship: Diamond Princess
Departure: 06 January 2023
Countries Visited: USA, Mexico
Twice As Nice
Inside
$1,722
Oceanview
$1,840
Balcony
$2,922
Suite
$4,002
From 1,722
View Trip
19 Day Canadian Rockies & West Coast USA with Scenic
Tour+Cruise

19 Days San Diego to Calgary
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 03 May 2023
Countries Visited: USA, Canada
Earlybird Saving + Early Payment Discount
Inside
-
Oceanview
-
Balcony
$24,959
Suite
$30,978
Save 2,206
From 24,959
View Trip
18 Day Panama Canal with Holland America
Cruise

18 Days (17 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Nieuw Amsterdam
Departure: 08 October 2022
Countries Visited: USA, Mexico, Guatemala, Nicaragua (+3 more), Costa Rica, Aruba, Bahamas
Have It All Offer
Inside
$4,299
Oceanview
$4,799
Balcony
$5,599
Suite
$12,559
From 4,299
View Trip
35 Day South Pacific Crossing with Holland America
Cruise

35 Days (34 Nights) San Diego to Sydney
Cruise Line: Holland America
Ship: Noordam
Departure: 08 October 2022
Countries Visited: USA, Kiribati, French Polynesia, Cook Islands (+2 more), Tonga, Australia
Have It All Offer
Inside
$8,799
Oceanview
$9,849
Balcony
$12,139
Suite
$15,049
From 8,799
View Trip
95 Day Grand Australia & New Zealand Voyage with Holland America
Cruise

95 Days (94 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Volendam
Departure: 03 January 2024
Countries Visited: USA, Kiribati, Samoa, Fiji (+9 more), Vanuatu, New Caledonia, Australia, Indonesia, New Zealand, Tonga, Niue, Cook Islands, French Polynesia
Advantage Fares
Inside
$24,669
Oceanview
$26,599
Balcony
$60,159
Suite
-
From 24,669
View Trip
8 Day Classic California Coast with Princess
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Princess
Ship: Diamond Princess
Departure: 18 September 2022
Countries Visited: USA, Mexico
Twice As Nice
Inside
$1,039
Oceanview
$1,103
Balcony
$1,369
Suite
$1,789
From 1,039
View Trip
6 Day West Coast Getaway with San Francisco with Princess
Cruise

6 Days (5 Nights) San Diego to San Diego
Cruise Line: Princess
Ship: Diamond Princess
Departure: 08 November 2022
Countries Visited: USA, Mexico
Twice As Nice
Inside
$615
Oceanview
$662
Balcony
$895
Suite
$1,015
From 615
View Trip
8 Day Mexican Riviera with Holland America
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departures: Nov 2022 to Jan 2023
Countries Visited: USA, Mexico
Have It All Offer
Inside
$1,349
Oceanview
$1,599
Balcony
$1,749
Suite
$2,199
From 1,349
View Trip
13 Day San Diego to Panama City with Norwegian Cruise Line
Cruise

13 Days (12 Nights) San Diego to Panama City
Ship: Norwegian Jewel
Departure: 14 January 2023
Countries Visited: USA, Mexico, Guatemala, Nicaragua (+2 more), Costa Rica, Panama
Take All 5 Free Offers + Save up to 35% + Double Your Money with CruiseFirst
Inside
$2,088
Oceanview
$2,371
Balcony
$3,221
Suite
$3,646
From 2,088
View Trip
8 Day Wine Country & Pacific Northwest with Holland America
Cruise

8 Days (7 Nights) San Diego to Vancouver
Cruise Line: Holland America
Ship: Koningsdam
Departure: 01 April 2023
Countries Visited: USA, Canada
Have It All Offer
Inside
$1,499
Oceanview
$1,699
Balcony
$1,849
Suite
$2,599
From 1,499
View Trip
8 Day Classic California Coast with Princess
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Princess
Ship: Diamond Princess
Departure: 25 September 2022
Countries Visited: USA, Mexico
Twice As Nice
Inside
$839
Oceanview
$892
Balcony
$989
Suite
$1,349
From 839
View Trip
16 Day Panama Canal Eastbound Cruise with Celebrity Cruises
Cruise

16 Days (15 Nights) San Diego to San Juan
Cruise Line: Celebrity Cruises
Ship: Celebrity Millennium
Departure: 30 September 2022
Countries Visited: USA, Mexico, Costa Rica, Colombia (+3 more), Aruba, Curacao, Puerto Rico
Cruise Only ratesWonderful Weekend Sale
Inside
$2,475
Oceanview
$2,675
Balcony
$3,565
Suite
$7,876
From 2,475
View Trip
6 Day Cabo San Lucas Getaway with Princess
Cruise

6 Days (5 Nights) San Diego to San Diego
Cruise Line: Princess
Ship: Diamond Princess
Departure: 06 September 2022
Countries Visited: USA, Mexico
Twice As Nice
Inside
$577
Oceanview
$618
Balcony
$877
Suite
$977
From 577
View Trip
11 Day Baja Peninsula & Sea of Cortez with Princess
Cruise

11 Days (10 Nights) San Diego to San Diego
Cruise Line: Princess
Ship: Diamond Princess
Departure: 17 December 2022
Countries Visited: USA, Mexico
Twice As Nice
Inside
$1,774
Oceanview
$1,928
Balcony
$2,634
Suite
$3,824
From 1,774
View Trip
21 Day Central America & Mexican Riviera with Princess
Cruise

21 Days (20 Nights) San Diego to San Diego
Cruise Line: Princess
Ship: Diamond Princess
Departure: 27 November 2022
Countries Visited: USA, Mexico, Nicaragua, Costa Rica (+2 more), Panama, Guatemala
Twice As Nice
Inside
$2,455
Oceanview
$2,649
Balcony
$3,875
Suite
$5,365
From 2,455
View Trip
11 Day Baja Peninsula & Sea of Cortez with Princess
Cruise

11 Days (10 Nights) San Diego to San Diego
Cruise Line: Princess
Ship: Diamond Princess
Departure: 27 December 2022
Countries Visited: USA, Mexico
Twice As Nice
Inside
$1,874
Oceanview
$2,016
Balcony
$2,874
Suite
$3,894
From 1,874
View Trip
8 Day Classic California Coast with Holland America
Cruise

8 Days (7 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 05 November 2022
Countries Visited: USA, Mexico
Have It All Offer
Inside
$1,599
Oceanview
$1,849
Balcony
$1,999
Suite
-
From 1,599
View Trip
12 Day San Diego to Puntarenas with Silversea
Cruise

12 Days (11 Nights) San Diego to Punta Arenas
Cruise Line: Silversea
Ship: Silver Wind
Departure: 16 October 2022
Countries Visited: USA, Mexico, Guatemala, Nicaragua (+1 more), Costa Rica
Port-To-Port All⁠ ⁠Inclusive
Inside
-
Oceanview
$6,950
Balcony
-
Suite
$18,100
From 6,950
View Trip
15 Day Panama Canal with Holland America
Cruise

15 Days (14 Nights) San Diego to Fort Lauderdale
Cruise Line: Holland America
Ship: Zuiderdam
Departure: 17 November 2022
Countries Visited: USA, Mexico, Guatemala, Nicaragua (+2 more), Costa Rica, Colombia
Have It All Offer
Inside
$3,649
Oceanview
$4,179
Balcony
$4,999
Suite
$6,649
From 3,649
View Trip
6 Day Mexican Riviera with Holland America
Cruise

6 Days (5 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 17 December 2022
Countries Visited: USA, Mexico
Advantage Fares
Inside
$899
Oceanview
$1,049
Balcony
$1,199
Suite
$1,699
From 899
View Trip
36 Day Hawaii, Tahiti & Marquesas with Holland America
Cruise

36 Days (35 Nights) San Diego to San Diego
Cruise Line: Holland America
Ship: Koningsdam
Departure: 18 February 2023
Countries Visited: USA, Kiribati, French Polynesia
Have It All Offer
Inside
$8,449
Oceanview
$9,239
Balcony
$13,099
Suite
$16,249
From 8,449
View Trip
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