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Cruises from Panama City

Choose from 15 cruises starting in Panama City, and travelling to Cusco, Fort Lauderdale, Lima, Los Angeles, Miami and more. February is the most popular month to cruise from Panama City and we have over 22 departures available from four leading cruise operators.
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9 Days
16 Days
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End City
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15 Cruises (22 Cruise Departures)
10 Day Southern Caribbean with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Panama City to Panama City
Ship: Norwegian Jewel
Departure: 20 March 2022
Countries Visited: Panama, Costa Rica, Aruba, Curacao (+2 more), Bonaire, Colombia
Break Free Sale
Inside
-
Oceanview
-
Balcony
$5,356
Suite
$6,443
From 5,356
View Trip
16 Day Peru to Panama Along the Andean Coast with Icons of Peru, a Luxury Journey with Scenic
Tour+Cruise

16 Days Panama City to Cusco
Operated By: Scenic
Ship: Scenic Eclipse
Departure: 26 October 2023
Countries Visited: Panama, Colombia, Ecuador, Peru
Earlybird Discount + Pay Early Saving
Inside
-
Oceanview
-
Balcony
$17,302
Suite
$22,540
Save 2,433
From 17,302
View Trip
10 Day Southern Caribbean with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Panama City to Panama City
Ship: Norwegian Jewel
Departure: 26 January 2023
Countries Visited: Panama, Colombia, Bonaire, Aruba (+2 more), Curacao, Costa Rica
Break Free Sale
Inside
$1,771
Oceanview
$2,167
Balcony
$2,996
Suite
$3,356
From 1,771
View Trip
10 Day Southern Caribbean with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Panama City to Panama City
Ship: Norwegian Jewel
Departure: 13 February 2023
Countries Visited: Panama, Colombia, Curacao, Aruba (+2 more), Bonaire, Costa Rica
Break Free Sale
Inside
$1,771
Oceanview
$2,167
Balcony
$2,987
Suite
$3,356
From 1,771
View Trip
11 Day Classic Panama Canal Passage with Viking Cruises
Cruise

11 Days (10 Nights) Panama City to Fort Lauderdale
Cruise Line: Viking Cruises
Ships: Viking Sky, Viking Star
Departures: Nov 2022 to Dec 2023
Countries Visited: USA, Mexico, Belize, Honduras (+2 more), Costa Rica, Panama
Welcome Back to the World
Inside
-
Oceanview
-
Balcony
$4,695
Suite
$7,295
Save 865
From 4,554
View Trip
9 Day Panama to Peru Along the Andean Coast with Scenic
Cruise

9 Days (8 Nights) Panama City to Lima
Cruise Line: Scenic
Ship: Scenic Eclipse
Departure: 26 October 2023
Countries Visited: Panama, Colombia, Ecuador, Peru
Earlybird Discount + Pay Early SavingEarlybird Saving
Inside
-
Oceanview
-
Balcony
$9,400
Suite
$13,718
Save 1,240
From 9,400
View Trip
11 Day Southern Caribbean with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Panama City to Panama City
Ship: Norwegian Jewel
Departure: 22 February 2023
Countries Visited: Panama, Costa Rica, Curacao, Bonaire (+2 more), Aruba, Colombia
Break Free Sale
Inside
$1,953
Oceanview
$2,349
Balcony
$3,288
Suite
$3,712
From 1,953
View Trip
13 Day Panama City to San Diego with Norwegian Cruise Line
Cruise

13 Days (12 Nights) Panama City to San Diego
Ship: Norwegian Jewel
Departures: Dec 2022 to Mar 2023
Countries Visited: Panama, Costa Rica, Nicaragua, El Salvador (+3 more), Guatemala, Mexico, USA
Break Free Sale
Inside
$2,443
Oceanview
$2,903
Balcony
$3,686
Suite
$4,220
From 2,443
View Trip
11 Day Taste Of The Caribbean with Oceania Cruises
Cruise

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 28 January 2023
Countries Visited: Panama, Colombia, Aruba, Curacao (+3 more), Jamaica, Cayman Islands, USA
Early Booking Savings + OLife Choice
Inside
$3,780
Oceanview
$4,120
Balcony
$5,960
Suite
-
Save 3,000
From 3,780
View Trip
10 Day Southern Caribbean with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Panama City to Panama City
Ship: Norwegian Jewel
Departure: 24 November 2022
Countries Visited: Panama, Colombia, Curacao, Bonaire (+2 more), Aruba, Costa Rica
Break Free Sale
Inside
$1,900
Oceanview
$2,167
Balcony
$3,116
Suite
$3,485
From 1,900
View Trip
9 Day Southern Caribbean with Norwegian Cruise Line
Cruise

9 Days (8 Nights) Panama City to Panama City
Ship: Norwegian Jewel
Departure: 04 March 2023
Countries Visited: Panama, Aruba, Curacao, Bonaire (+1 more), Costa Rica
Break Free Sale
Inside
$1,623
Oceanview
$1,991
Balcony
$2,765
Suite
$3,096
From 1,623
View Trip
11 Day Panama Potpourri with Oceania Cruises
Cruise

11 Days (10 Nights) Panama City to Miami
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 01 February 2022
Countries Visited: Panama, Costa Rica, Honduras, Guatemala (+3 more), Belize, Mexico, USA
Early Booking Savings + OLife Choice
Inside
-
Oceanview
-
Balcony
$6,380
Suite
$8,130
Save 3,500
From 6,380
View Trip
10 Day Southern Caribbean with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Panama City to Panama City
Ship: Norwegian Jewel
Departures: Dec 2022 to Mar 2023
Countries Visited: Panama, Costa Rica, Curacao, Aruba (+2 more), Bonaire, Colombia
Break Free Sale
Inside
$1,783
Oceanview
$2,179
Balcony
$2,998
Suite
$3,395
From 1,783
View Trip
12 Day Panama City to New York with Norwegian Cruise Line
Cruise

12 Days (11 Nights) Panama City to New York
Ship: Norwegian Gem
Departures: Jan 2023 to Feb 2023
Countries Visited: Panama, Costa Rica, Aruba, Curacao (+3 more), Dominican Republic, Turks and Caicos Islands, USA
Break Free Sale
Inside
$2,257
Oceanview
$2,607
Balcony
$3,298
Suite
$3,796
From 2,257
View Trip
13 Day Central American Discovery with Scenic
Cruise

13 Days (12 Nights) Panama City to Los Angeles
Cruise Line: Scenic
Ship: Scenic Eclipse
Departure: 04 April 2023
Countries Visited: Panama, Costa Rica, Nicaragua, El Salvador (+3 more), Guatemala, Mexico, USA
Earlybird Discount + Pay Early SavingEarlybird Saving
Inside
-
Oceanview
-
Balcony
$14,030
Suite
$20,859
Save 1,839
From 14,351
View Trip
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